combat
Correct batch effects in single-cell RNA sequencing data using a categorical annotation key and optional covariates, enabling accurate downstream analysis without manual coding.
Instructions
ComBat function for batch effect correction
Input Schema
Name | Required | Description | Default |
---|---|---|---|
covariates | No | Additional covariates besides the batch variable such as adjustment variables or biological condition. | |
key | No | Key to a categorical annotation from adata.obs that will be used for batch effect removal. | batch |