Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?
Annotations already declare destructiveHint=true, idempotentHint=true and readOnlyHint=false, so the mutation profile is covered; the description adds no context beyond that, such as that atom counts and coordinates change, that existing hydrogens are retained or replaced, or that failures can occur on residues lacking templates. "Adds" is at least consistent with destructiveHint, so there is no contradiction.
Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.