Bioinformatics
Tools for computational analysis of biological data, including genomics, proteomics, and other molecular biology data. Enables access to bioinformatics pipelines, algorithms, and databases.
MCP ServersBrowse all →
- AlicenseAqualityAmaintenanceA stateless, deterministic Bio-Robotics Core Engine converting biological data (UniProt API) to G-code.Last updated266MIT

Noctua MCP Serverofficial
AlicenseAqualityCmaintenanceEnables editing and querying of Gene Ontology Causal Activity Models (GO-CAMs) through the Barista API. Supports model creation, individual and fact management, evidence addition, and causal pathway construction for biological knowledge representation.Last updated18BSD 3-Clause- AlicenseAqualityCmaintenanceAn MCP server that provides standardized access to biomedical knowledge bases and resources, enabling AI systems to retrieve verified information from sources like bioRxiv, EuropePMC, and various protein/gene databases.Last updated5228Apache 2.0

PDBe MCP Serversofficial
AlicenseAqualityAmaintenanceProvides seamless access to the Protein Data Bank in Europe (PDBe) API and search capabilities, enabling AI clients to query protein structures, perform advanced searches, and retrieve structural biology data.Last updated3336Apache 2.0- AlicenseAqualityDmaintenanceEnables AI-driven pharmacogenomic analysis by querying structured genetic variant, drug response, and disease risk data. Supports natural language questions about medications, traits, and health risks based on user genome data, with privacy-first local execution.Last updated169010MIT

WormBase MCP Serverofficial
AlicenseAqualityDmaintenanceEnables querying the WormBase database for C. elegans and nematode genomics data, including gene information, protein sequences, phenotypes, interactions, and expression patterns through natural language.Last updated121MIT- AlicenseAqualityAmaintenanceAn MCP server that interfaces with Gigwa for genotyping data import, analysis, and audit, enabling users to perform complex workflows through natural language commands.Last updated4229Apache 2.0

millimap-mcpofficial
AlicenseAqualityCmaintenanceEnables Claude Desktop to read and drive analyses on the active MilliMap session, including datasets, clusters, annotations, and markers.Last updated12MIT- AlicenseBqualityDmaintenanceProvides access to the STRING protein-protein interaction database for mapping identifiers, retrieving interaction networks, and performing functional enrichment analysis. It enables users to explore protein partners, pathways, and cross-species homology through natural language interactions.Last updated91ISC
- AlicenseAqualityFmaintenanceAn MCP server that enables AI coding assistants to interact with Rosetta, PyRosetta, and Biotite for running RosettaScripts, validating XML, translating between Rosetta and Biotite, scoring structures, and querying documentation.Last updated1923816MIT
- AlicenseAqualityDmaintenanceEnables AI assistants to query the Ubergraph biomedical ontology SPARQL endpoint with tools for custom SPARQL queries, term lookup, search, and hierarchy traversal.Last updated4MIT
- AlicenseAqualityBmaintenanceMCP server that provides tools to query harmonized gene-disease validity data from the Gene Curation Coalition, supporting consensus and conflict detection for gene-disease assertions.Last updated12MIT
- AlicenseAqualityDmaintenanceEnables the generation, mutation, and evolution of DNA and protein sequences using various evolutionary models and phylogenetic algorithms. It supports realistic next-generation sequencing read simulation and population-level evolutionary tracking for bioinformatics research and testing.Last updated6BSD 2-Clause "Simplified"
- AlicenseBqualityDmaintenanceEnables searching, retrieving, and downloading protein structure data from the RCSB Protein Data Bank. Supports intelligent protein structure search, comprehensive data retrieval, and multiple file format downloads for bioinformatics research.Last updated3MIT
- AlicenseBqualityDmaintenanceProvides access to the Ensembl genomics REST API with 30+ tools for genomic data including gene lookup, sequence retrieval, genetic variants, cross-species homology, phenotypes, and regulatory features.Last updated25ISC
- AlicenseAqualityDmaintenanceA Model Context Protocol server that interfaces with Biomart databases, allowing models to discover biological datasets, explore attributes/filters, retrieve biological data, and translate between different biological identifiers.Last updated87MIT
- AlicenseAqualityAmaintenanceEmpowers AI agents with direct access to the official ClinicalTrials.gov database, enabling programmatic searching, retrieval, and analysis of clinical study data through a Model Context Protocol interface.Last updated71,39381Apache 2.0
- AlicenseAqualityCmaintenanceProvides an MCP interface to the ROBOT command-line tool for OWL ontology editing, enabling operations like merging, reasoning, and conversion via natural language.Last updated261BSD 2-Clause "Simplified"
- AlicenseAqualityBmaintenanceIntegrates AlphaFold DB and eight other biomedical data sources into MCP tools for variant clinical reporting, disease-target analysis, structural intelligence, and drug repurposing, with results persisted to a local SQLite knowledge graph.Last updated293Apache 2.0
- AlicenseBqualityFmaintenanceProvides comprehensive access to the UCSC Genome Browser API, enabling queries of genomic data, DNA sequences, gene annotations, variants, and metadata across multiple species and assemblies.Last updated126MIT
- AlicenseAqualityCmaintenanceA framework that integrates Brain-Computer Interface technology with the Model Context Protocol to enable real-time neural signal processing and AI-powered interactions for healthcare, accessibility, and research applications.Last updated1211MIT
- AlicenseBqualityDmaintenanceEnables AI-powered genomic variant analysis including variant impact prediction, regulatory element discovery, and batch variant scoring. Currently operates in mock mode as a proof-of-concept awaiting the public release of Google DeepMind's AlphaGenome API.Last updated20142MIT
- AlicenseBqualityDmaintenanceMCP server providing access to the BERtron API for aggregating genomic and environmental data from multiple BER data sources, enabling geospatial search and health checks.Last updated83BSD 3-Clause
- AlicenseAqualityCmaintenanceMCP server for polygenic risk score analysis, wrapping just-prs to enable catalog search, PRS computation, VCF normalization, percentile and risk estimation, and quality assessment.Last updated101MIT
- AlicenseBqualityDmaintenanceEnables AI assistants to access protein information directly from UniProt, allowing retrieval of protein names, functions, sequences, and organism data by accession number.Last updated213MIT
- AlicenseAqualityAmaintenanceAn MCP server that grounds protein research in the UniProt SPARQL endpoint, providing tools for querying proteins, sequences, variants, diseases, and more via intent-named tools and raw SPARQL.Last updated15MIT
- AlicenseBqualityDmaintenanceMCP server that exposes DECIMER image-to-SMILES functionality as tool calls.Last updated2MIT
- AlicenseAqualityCmaintenanceProvides direct SQL access to a locally hosted Reactome database, enabling schema discovery, guarded read-only queries, and ergonomic helpers over the full relational schema.Last updated9MIT
- AlicenseBqualityDmaintenanceA Model Context Protocol server that provides tools for interacting with the STRING database to analyze protein-protein interaction networks and functional enrichment. It enables users to map protein identifiers, retrieve interaction data, and generate biological network visualizations through natural language interfaces.Last updated113BSD 3-Clause
- AlicenseAqualityBmaintenanceConverts natural language queries into Cypher queries against the NASA GeneLab Knowledge Graph, enabling AI-assisted analysis of spaceflight experiments and their biological effects.Last updated123BSD 3-Clause
MCP ConnectorsBrowse all →
Search GBIF species taxonomy, occurrence records, datasets, and publishers.
Look up genes, fetch sequences, predict variant consequences, find orthologs and xrefs via Ensembl.
Hosted DNA/RNA/protein tools: primers, oligos, PCR, cloning, CRISPR, alignment, batch & pipelines.
Canine genomics for agents: breed allele frequencies, AI pathogenicity + OMIA clinical disease layer
RCSB PDB MCP — experimentally determined macromolecular structures.
UniProt MCP — protein sequence + function database.
Biotech intelligence for AI agents: drugs, targets, diagnostics, PoS estimates, and writeups.
InterPro MCP (EBI) — protein family / domain / functional-site classification.
Biomedical data: compounds, drug info, and molecular targets
EBI PRIDE Archive MCP — proteomics (mass-spectrometry) data repository.
Query STRING interactions, enrichment, annotations, homology, and PPI networks.
Rhea MCP — expert-curated database of biochemical reactions.