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UniProt MCP — protein sequence + function database.

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Status
Unhealthy
Last Tested
Transport
Streamable HTTP
URL
Repository
pipeworx-io/mcp-uniprot
GitHub Stars
0
Server Listing
mcp-uniprot

TDQS

A3.9/5.0

Scored across 37 tools

Disambiguation3/5

The UniProt-specific tools (get, search, feature_summary, keyword, proteomes_search, taxonomy_search) are clearly distinct, and the entity tools (resolve_entity, entity_profile, compare_entities, recent_changes) are well-differentiated by description. However, the routing/meta family overlaps heavily — ask_pipeworx, ask_pipeworx_beta (explicitly stated to match ask_pipeworx exactly right now), ask_pipeworx_grounded, and deep_research all answer questions against the same catalog — and the five polymarket_* tools (edges vs arbitrage especially) have fuzzy boundaries that will cause misselection.

Naming Consistency4/5

Almost everything is consistent snake_case (ask_pipeworx_grounded, entity_profile, resolve_entity, polymarket_fill_risk, list_subscriptions), with the polymarket_* prefix applied predictably. Minor deviations exist — several bare single-word tools (get, search, keyword, remember, recall, forget, subscribe) don't follow the verb_noun pattern of their siblings, but no camelCase/snake_case mixing occurs.

Tool Count3/5

37 tools is heavy and sits above the comfortable range, and there is a notable mismatch: the server is named 'Uniprot' yet only 6 of the 37 tools are protein-related, with the remainder being a broad Pipeworx data-gateway grab-bag. The polymarket and meta-tool families each contribute enough tools that some feel redundant (ask_pipeworx_beta, discover_tools vs suggest_questions).

Completeness3/5

For the UniProt domain the surface covers the core needs — entry retrieval, search, features, keywords, proteomes, taxonomy — but lacks an ID-mapping tool and cross-reference-specific lookup, which are common UniProt operations. Across the broader gateway surface coverage is inconsistent: memory, subscriptions/alerts, entity resolution, and Polymarket analysis are well populated, while many advertised data domains (FDA, FRED, patents) are reachable only through the generic router rather than dedicated tools.

Tool Schema Changelog

Recent tool additions, removals, and schema changes observed during successful MCP inspections.

  1. 1 tool update
    • Changedbet_research2 fields changed
      • changedInput schema / examples
        Previous value: -[
        -  {
        -    "market": "when-will-bitcoin-hit-150k"
        -  },
        -  {
        -    "market": "https://polymarket.com/event/when-will-bitcoin-hit-150k"
        -  }
        -]New value: +[
        +  {
        +    "market": "will-kristi-noem-win-the-2028-republican-presidential-nomination"
        +  },
        +  {
        +    "market": "https://polymarket.com/event/will-kristi-noem-win-the-2028-republican-presidential-nomination"
        +  }
        +]
      • changedInput schema / properties / market / description
        Previous value: -"Polymarket slug (\"when-will-bitcoin-hit-150k\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k?\"). Dated slugs stop resolving once they settle — Polymarket de-indexes resolved markets — so prefer an undated one."New value: +"Polymarket slug (\"will-kristi-noem-win-the-2028-republican-presidential-nomination\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k?\"). Dated slugs stop resolving once they settle — Polymarket de-indexes resolved markets — so prefer an undated one."
  2. 2 tool updates
    • Changedbet_research2 fields changed
      • changedInput schema / examples
        Previous value: -[
        -  {
        -    "market": "will-bitcoin-reach-100k-in-july-2026"
        -  },
        -  {
        -    "market": "https://polymarket.com/event/will-bitcoin-hit-150k-by-june-30-2026"
        -  }
        -]New value: +[
        +  {
        +    "market": "when-will-bitcoin-hit-150k"
        +  },
        +  {
        +    "market": "https://polymarket.com/event/when-will-bitcoin-hit-150k"
        +  }
        +]
      • changedInput schema / properties / market / description
        Previous value: -"Polymarket slug (\"will-bitcoin-hit-150k-by-june-30-2026\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k by June 30?\")"New value: +"Polymarket slug (\"when-will-bitcoin-hit-150k\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k?\"). Dated slugs stop resolving once they settle — Polymarket de-indexes resolved markets — so prefer an undated one."
    • Changedpolymarket_kalshi_spread2 fields changed
      • changedInput schema / examples
        Previous value: -[
        -  {
        -    "topic": "fed"
        -  },
        -  {
        -    "topic": "btc"
        -  }
        -]New value: +[
        +  {
        +    "topic": "fed"
        +  },
        +  {
        +    "topic": "btc"
        +  },
        +  {
        +    "topic": "bitcoin"
        +  },
        +  {
        +    "topic": "fed rate decision"
        +  }
        +]
      • changedInput schema / properties / topic / description
        Previous value: -"Pre-mapped: fed | btc | cpi | gdp | sp500 | recession | next_pope | next_uk_pm | next_israel_pm | 2028_president"New value: +"Subject to compare. Canonical keys: fed | btc | eth | cpi | gdp | sp500 | recession | next_pope | next_uk_pm | next_israel_pm | 2028_president — but aliases and keywords resolve too (\"bitcoin\", \"fed rate decision\", \"ethereum\", \"inflation\", \"s&p 500\", \"us recession\", \"next pope\", \"2028 election\"). Check resolution.topic_matched_by in the response: \"exact\"/\"alias\" is a curated pairing, \"phrase\"/\"token\" is a keyword guess."

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