Gnomad
Server Details
gnomAD MCP — Broad Institute Genome Aggregation Database (GraphQL).
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- Status
- Unhealthy
- Uptime
- 41.4% over 41 days
- Last Tested
- Transport
- Streamable HTTP
- URL
- Repository
- pipeworx-io/mcp-gnomad
- GitHub Stars
- 0
- Server Listing
- mcp-gnomad
TDQS
Scored across 41 tools
Multiple tools have unclear boundaries: ask_pipeworx, ask_pipeworx_beta, ask_pipeworx_grounded, and deep_research all answer questions with only subtle differentiators, and the polymarket family (arbitrage, edges, edge_tracker, fill_risk, kalshi_spread, bet_research) heavily overlaps. Company-data tools (entity_profile, company_facts, compare_entities, recent_changes) and AI-visibility tools (ai_visibility_check, scan_competitor_ai_presence) also blur together.
Naming is mostly snake_case but follows no consistent pattern: verb_noun (validate_claim, generate_llms_txt), bare nouns (gene, variant, region, transcript), brand-style phrases (ask_pipeworx, bet_research), and mixed verb families (scan_ vs resolve_ vs generate_). Prefix families like ask_pipeworx_* and polymarket_* are internally consistent, but cross-family conventions are unpredictable.
41 tools is far too many for a coherent server, and the count is inflated by at least five distinct domains: gnomAD genetics, Pipeworx data routing, prediction markets, memory/subscriptions, and AI-marketing utilities. The server would need to be split into several focused servers to be well-scoped.
The server name implies gnomAD genetics, but only 5 of 41 tools serve that domain, and they cover basic gene/variant/region lookups while omitting major gnomAD surface areas like coverage, constraint, population frequencies, and structural variants. For the broader data-platform scope, the prediction-market and company clusters are reasonably covered, but the lack of a single coherent domain makes meaningful completeness impossible.
Tool Schema Changelog
Recent tool additions, removals, and schema changes observed during successful MCP inspections.
22 tool updates
- Changed
ai_visibility_check1 field changed- added
Input schema / examplesAdded value: +[ + { + "entity": "Tesla" + } +]
- Changed
ask_pipeworx_beta1 field changed- added
Input schema / examplesAdded value: +[ + { + "question": "What is the current US unemployment rate?" + } +]
- Changed
ask_pipeworx_grounded1 field changed- added
Input schema / examplesAdded value: +[ + { + "question": "What was Apple's fiscal 2023 revenue?" + } +]
- Changed
company_facts5 fields changed- added
Input schema / examplesAdded value: +[ + { + "attribute": "revenue", + "company": "AAPL", + "period": { + "fiscal_year": 2023, + "type": "annual" + } + } +] - added
Input schema / properties / as_ofAdded value: +{ + "description": "Past ISO timestamp with timezone. Replay the latest answer actually recorded by that instant; no invented history or live fallback.", + "type": "string" +} - added
Input schema / properties / exclude_publishersAdded value: +{ + "description": "Publisher ids forbidden for fact retrieval: sec, fmp, alphavantage. Case and surrounding whitespace are normalized; unknown ids are refused. Excluding sec currently leaves no eligible fact source and returns unavailable/sources_excluded with the selection reasons. Identity and fiscal-calendar lookups may still use SEC; no excluded financial concept is fetched.", + "items": { + "type": "string" + }, + "type": "array" +} - added
Input schema / properties / freshnessAdded value: +{ + "description": "cached (default) permits an eligible stored answer; fresh requires an upstream refresh and never silently falls back to stale data.", + "enum": [ + "cached", + "fresh" + ], + "type": "string" +} - added
Input schema / properties / max_ageAdded value: +{ + "description": "Maximum age in seconds of the upstream publication, not our fetch. Older or undated facts are withheld.", + "maximum": 3155760000, + "minimum": 0, + "type": "number" +}
- Changed
compare_entities1 field changed- added
Input schema / examplesAdded value: +[ + { + "type": "company", + "values": [ + "AAPL", + "MSFT" + ] + } +]
- Changed
deep_research1 field changed- added
Input schema / examplesAdded value: +[ + { + "depth": "quick", + "question": "What is the current US unemployment rate and how has it changed over the past year?" + } +]
- Changed
entity_profile1 field changed- added
Input schema / examplesAdded value: +[ + { + "type": "company", + "value": "AAPL" + } +]
- Changed
generate_llms_txt1 field changed- added
Input schema / examplesAdded value: +[ + { + "url": "https://pipeworx.io" + } +]
- Changed
pipeworx_feedback1 field changed- added
Input schema / examplesAdded value: +[ + { + "message": "Fleet #2184 smoke test: verifying pipeworx_feedback example call returns non-empty.", + "type": "other" + } +]
- Changed
pipeworx_trending1 field changed- added
Input schema / examplesAdded value: +[ + { + "window": "7d" + } +]
- Changed
polymarket_arbitrage1 field changed- added
Input schema / examplesAdded value: +[ + { + "topic": "Fed rate decision" + } +]
- Changed
polymarket_edge_tracker1 field changed- added
Input schema / examplesAdded value: +[ + { + "days": 14, + "window": "1wk" + } +]
- Changed
polymarket_edges3 fields changed- added
Input schema / examplesAdded value: +[ + { + "limit": 5, + "window": "1wk" + } +] - changed
Input schema / properties / min_edge_pp / descriptionPrevious value: -"Minimum |edge| in percentage points to include (default 0.5). Edge is evaluated NET of slippage."New value: +"Minimum |edge| in percentage points to include (default 0.5). Edge is evaluated NET of slippage and Polymarket's own taker fee." - changed
Input schema / properties / slippage_pp / descriptionPrevious value: -"Assumed execution slippage in percentage points per leg (default 0.3). Subtracted from raw |edge| before ranking and Kelly sizing. Polymarket has zero trading fees as of 2024 but bid/ask + thin depth typically eats 20-50bp per trade. Bump for very thin partitions; drop to 0 if you have a smarter fill model."New value: +"Assumed execution slippage in percentage points per leg (default 0.3), for bid/ask + thin depth cost that a last-trade price does not show. Subtracted from raw |edge| before ranking and Kelly sizing, ON TOP OF Polymarket's own taker fee — which is NOT zero (rate 0.04-0.07 depending on category, read off each market's own published fee schedule; see fees_pp_applied on every row and fees.ts for the full schedule). Bump slippage for very thin partitions; drop to 0 if you have a smarter fill model — the fee still applies regardless."
- Changed
polymarket_fill_risk1 field changed- added
Input schema / examplesAdded value: +[ + { + "market": "will-the-fed-increase-interest-rates-by-25-bps-after-the-december-2026-meeting-20260729232808636", + "side": "buy_yes", + "size_usd": 1000 + } +]
- Changed
recent_changes1 field changed- added
Input schema / examplesAdded value: +[ + { + "since": "30d", + "type": "company", + "value": "AAPL" + } +]
- Changed
remember1 field changed- added
Input schema / examplesAdded value: +[ + { + "key": "target_ticker", + "value": "AAPL" + } +]
- Changed
resolve_entity1 field changed- added
Input schema / examplesAdded value: +[ + { + "type": "company", + "value": "AAPL" + } +]
- Changed
scan_competitor_ai_presence1 field changed- added
Input schema / examplesAdded value: +[ + { + "entities": [ + "Pipeworx", + "Zapier" + ] + } +]
- Changed
scan_dependency1 field changed- added
Input schema / examplesAdded value: +[ + { + "package": "left-pad" + } +]
- Changed
search_within1 field changed- added
Input schema / examplesAdded value: +[ + { + "query": "supply-chain risk", + "text": "Apple Inc. reported fiscal 2023 revenue of $383.285 billion, driven by strong iPhone and Services growth. Net income was $96.995 billion. The company faced supply-chain risk in China during the quarter." + } +]
- Changed
suggest_questions1 field changed- added
Input schema / examplesAdded value: +[ + { + "topic": "finance" + } +]
- Changed
validate_claim1 field changed- added
Input schema / examplesAdded value: +[ + { + "claim": "Apple's fiscal 2023 revenue was $383 billion" + } +]
8 tool updates
- Added
company_facts - Changed
gene3 fields changed- changed
Output schema / properties / gene / properties / variants / items / properties / exome / typePrevious value: -"object"New value: +[ + "object", + "null" +] - changed
Output schema / properties / gene / properties / variants / items / properties / genome / typePrevious value: -"object"New value: +[ + "object", + "null" +] - changed
Output schema / properties / gene / properties / variants / items / properties / hgvsp / typePrevious value: -"string"New value: +[ + "string", + "null" +]
- Added
kalshi_weather_edge - Changed
region1 field changed- changed
Output schema / properties / region / properties / variants / items / properties / exome / typePrevious value: -"object"New value: +[ + "object", + "null" +]
- Added
release_calendar_markets - Added
resolution_audit - Added
resolution_diff - Changed
variant2 fields changed- changed
Output schema / properties / variant / properties / transcript_consequences / items / properties / hgvsp / typePrevious value: -"string"New value: +[ + "string", + "null" +] - changed
Output schema / properties / variant / properties / transcript_consequences / items / properties / is_canonical / typePrevious value: -"boolean"New value: +[ + "boolean", + "null" +]
1 tool update
- Changed
bet_research2 fields changed- changed
Input schema / examplesPrevious value: -[ - { - "market": "when-will-bitcoin-hit-150k" - }, - { - "market": "https://polymarket.com/event/when-will-bitcoin-hit-150k" - } -]New value: +[ + { + "market": "will-kristi-noem-win-the-2028-republican-presidential-nomination" + }, + { + "market": "https://polymarket.com/event/will-kristi-noem-win-the-2028-republican-presidential-nomination" + } +] - changed
Input schema / properties / market / descriptionPrevious value: -"Polymarket slug (\"when-will-bitcoin-hit-150k\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k?\"). Dated slugs stop resolving once they settle — Polymarket de-indexes resolved markets — so prefer an undated one."New value: +"Polymarket slug (\"will-kristi-noem-win-the-2028-republican-presidential-nomination\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k?\"). Dated slugs stop resolving once they settle — Polymarket de-indexes resolved markets — so prefer an undated one."
1 tool update
- Changed
polymarket_kalshi_spread1 field changed- changed
Input schema / examplesPrevious value: -[ - { - "topic": "fed" - }, - { - "topic": "btc" - } -]New value: +[ + { + "topic": "fed" + }, + { + "topic": "btc" + }, + { + "topic": "bitcoin" + }, + { + "topic": "fed rate decision" + } +]
2 tool updates
- Changed
bet_research2 fields changed- changed
Input schema / examplesPrevious value: -[ - { - "market": "will-bitcoin-reach-100k-in-july-2026" - }, - { - "market": "https://polymarket.com/event/will-bitcoin-hit-150k-by-june-30-2026" - } -]New value: +[ + { + "market": "when-will-bitcoin-hit-150k" + }, + { + "market": "https://polymarket.com/event/when-will-bitcoin-hit-150k" + } +] - changed
Input schema / properties / market / descriptionPrevious value: -"Polymarket slug (\"will-bitcoin-hit-150k-by-june-30-2026\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k by June 30?\")"New value: +"Polymarket slug (\"when-will-bitcoin-hit-150k\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k?\"). Dated slugs stop resolving once they settle — Polymarket de-indexes resolved markets — so prefer an undated one."
- Changed
polymarket_kalshi_spread1 field changed- changed
Input schema / properties / topic / descriptionPrevious value: -"Pre-mapped: fed | btc | cpi | gdp | sp500 | recession | next_pope | next_uk_pm | next_israel_pm | 2028_president"New value: +"Subject to compare. Canonical keys: fed | btc | eth | cpi | gdp | sp500 | recession | next_pope | next_uk_pm | next_israel_pm | 2028_president — but aliases and keywords resolve too (\"bitcoin\", \"fed rate decision\", \"ethereum\", \"inflation\", \"s&p 500\", \"us recession\", \"next pope\", \"2028 election\"). Check resolution.topic_matched_by in the response: \"exact\"/\"alias\" is a curated pairing, \"phrase\"/\"token\" is a keyword guess."
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