Skip to main content
Glama

Server Details

gnomAD MCP — Broad Institute Genome Aggregation Database (GraphQL).

Glama couldn't complete the latest health check. If this server requires authentication, missing or expired test credentials may be the cause. A test profile lets Glama authenticate for health checks and discover tools; it is separate from your personal connections.

If you are the author, claim ownership, then add or update a test profile under Admin → Test Profile.

Status
Unhealthy
Uptime
41.4% over 41 days
Last Tested
Transport
Streamable HTTP
URL
Repository
pipeworx-io/mcp-gnomad
GitHub Stars
0
Server Listing
mcp-gnomad

TDQS

A3.5/5.0

Scored across 41 tools

Disambiguation2/5

Multiple tools have unclear boundaries: ask_pipeworx, ask_pipeworx_beta, ask_pipeworx_grounded, and deep_research all answer questions with only subtle differentiators, and the polymarket family (arbitrage, edges, edge_tracker, fill_risk, kalshi_spread, bet_research) heavily overlaps. Company-data tools (entity_profile, company_facts, compare_entities, recent_changes) and AI-visibility tools (ai_visibility_check, scan_competitor_ai_presence) also blur together.

Naming Consistency2/5

Naming is mostly snake_case but follows no consistent pattern: verb_noun (validate_claim, generate_llms_txt), bare nouns (gene, variant, region, transcript), brand-style phrases (ask_pipeworx, bet_research), and mixed verb families (scan_ vs resolve_ vs generate_). Prefix families like ask_pipeworx_* and polymarket_* are internally consistent, but cross-family conventions are unpredictable.

Tool Count2/5

41 tools is far too many for a coherent server, and the count is inflated by at least five distinct domains: gnomAD genetics, Pipeworx data routing, prediction markets, memory/subscriptions, and AI-marketing utilities. The server would need to be split into several focused servers to be well-scoped.

Completeness2/5

The server name implies gnomAD genetics, but only 5 of 41 tools serve that domain, and they cover basic gene/variant/region lookups while omitting major gnomAD surface areas like coverage, constraint, population frequencies, and structural variants. For the broader data-platform scope, the prediction-market and company clusters are reasonably covered, but the lack of a single coherent domain makes meaningful completeness impossible.

Tool Schema Changelog

Recent tool additions, removals, and schema changes observed during successful MCP inspections.

  1. 22 tool updates
    • Changedai_visibility_check1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "entity": "Tesla"
        +  }
        +]
    • Changedask_pipeworx_beta1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "question": "What is the current US unemployment rate?"
        +  }
        +]
    • Changedask_pipeworx_grounded1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "question": "What was Apple's fiscal 2023 revenue?"
        +  }
        +]
    • Changedcompany_facts5 fields changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "attribute": "revenue",
        +    "company": "AAPL",
        +    "period": {
        +      "fiscal_year": 2023,
        +      "type": "annual"
        +    }
        +  }
        +]
      • addedInput schema / properties / as_of
        Added value: +{
        +  "description": "Past ISO timestamp with timezone. Replay the latest answer actually recorded by that instant; no invented history or live fallback.",
        +  "type": "string"
        +}
      • addedInput schema / properties / exclude_publishers
        Added value: +{
        +  "description": "Publisher ids forbidden for fact retrieval: sec, fmp, alphavantage. Case and surrounding whitespace are normalized; unknown ids are refused. Excluding sec currently leaves no eligible fact source and returns unavailable/sources_excluded with the selection reasons. Identity and fiscal-calendar lookups may still use SEC; no excluded financial concept is fetched.",
        +  "items": {
        +    "type": "string"
        +  },
        +  "type": "array"
        +}
      • addedInput schema / properties / freshness
        Added value: +{
        +  "description": "cached (default) permits an eligible stored answer; fresh requires an upstream refresh and never silently falls back to stale data.",
        +  "enum": [
        +    "cached",
        +    "fresh"
        +  ],
        +  "type": "string"
        +}
      • addedInput schema / properties / max_age
        Added value: +{
        +  "description": "Maximum age in seconds of the upstream publication, not our fetch. Older or undated facts are withheld.",
        +  "maximum": 3155760000,
        +  "minimum": 0,
        +  "type": "number"
        +}
    • Changedcompare_entities1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "type": "company",
        +    "values": [
        +      "AAPL",
        +      "MSFT"
        +    ]
        +  }
        +]
    • Changeddeep_research1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "depth": "quick",
        +    "question": "What is the current US unemployment rate and how has it changed over the past year?"
        +  }
        +]
    • Changedentity_profile1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "type": "company",
        +    "value": "AAPL"
        +  }
        +]
    • Changedgenerate_llms_txt1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "url": "https://pipeworx.io"
        +  }
        +]
    • Changedpipeworx_feedback1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "message": "Fleet #2184 smoke test: verifying pipeworx_feedback example call returns non-empty.",
        +    "type": "other"
        +  }
        +]
    • Changedpipeworx_trending1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "window": "7d"
        +  }
        +]
    • Changedpolymarket_arbitrage1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "topic": "Fed rate decision"
        +  }
        +]
    • Changedpolymarket_edge_tracker1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "days": 14,
        +    "window": "1wk"
        +  }
        +]
    • Changedpolymarket_edges3 fields changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "limit": 5,
        +    "window": "1wk"
        +  }
        +]
      • changedInput schema / properties / min_edge_pp / description
        Previous value: -"Minimum |edge| in percentage points to include (default 0.5). Edge is evaluated NET of slippage."New value: +"Minimum |edge| in percentage points to include (default 0.5). Edge is evaluated NET of slippage and Polymarket's own taker fee."
      • changedInput schema / properties / slippage_pp / description
        Previous value: -"Assumed execution slippage in percentage points per leg (default 0.3). Subtracted from raw |edge| before ranking and Kelly sizing. Polymarket has zero trading fees as of 2024 but bid/ask + thin depth typically eats 20-50bp per trade. Bump for very thin partitions; drop to 0 if you have a smarter fill model."New value: +"Assumed execution slippage in percentage points per leg (default 0.3), for bid/ask + thin depth cost that a last-trade price does not show. Subtracted from raw |edge| before ranking and Kelly sizing, ON TOP OF Polymarket's own taker fee — which is NOT zero (rate 0.04-0.07 depending on category, read off each market's own published fee schedule; see fees_pp_applied on every row and fees.ts for the full schedule). Bump slippage for very thin partitions; drop to 0 if you have a smarter fill model — the fee still applies regardless."
    • Changedpolymarket_fill_risk1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "market": "will-the-fed-increase-interest-rates-by-25-bps-after-the-december-2026-meeting-20260729232808636",
        +    "side": "buy_yes",
        +    "size_usd": 1000
        +  }
        +]
    • Changedrecent_changes1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "since": "30d",
        +    "type": "company",
        +    "value": "AAPL"
        +  }
        +]
    • Changedremember1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "key": "target_ticker",
        +    "value": "AAPL"
        +  }
        +]
    • Changedresolve_entity1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "type": "company",
        +    "value": "AAPL"
        +  }
        +]
    • Changedscan_competitor_ai_presence1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "entities": [
        +      "Pipeworx",
        +      "Zapier"
        +    ]
        +  }
        +]
    • Changedscan_dependency1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "package": "left-pad"
        +  }
        +]
    • Changedsearch_within1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "query": "supply-chain risk",
        +    "text": "Apple Inc. reported fiscal 2023 revenue of $383.285 billion, driven by strong iPhone and Services growth. Net income was $96.995 billion. The company faced supply-chain risk in China during the quarter."
        +  }
        +]
    • Changedsuggest_questions1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "topic": "finance"
        +  }
        +]
    • Changedvalidate_claim1 field changed
      • addedInput schema / examples
        Added value: +[
        +  {
        +    "claim": "Apple's fiscal 2023 revenue was $383 billion"
        +  }
        +]
  2. 8 tool updates
    • Addedcompany_facts
    • Changedgene3 fields changed
      • changedOutput schema / properties / gene / properties / variants / items / properties / exome / type
        Previous value: -"object"New value: +[
        +  "object",
        +  "null"
        +]
      • changedOutput schema / properties / gene / properties / variants / items / properties / genome / type
        Previous value: -"object"New value: +[
        +  "object",
        +  "null"
        +]
      • changedOutput schema / properties / gene / properties / variants / items / properties / hgvsp / type
        Previous value: -"string"New value: +[
        +  "string",
        +  "null"
        +]
    • Addedkalshi_weather_edge
    • Changedregion1 field changed
      • changedOutput schema / properties / region / properties / variants / items / properties / exome / type
        Previous value: -"object"New value: +[
        +  "object",
        +  "null"
        +]
    • Addedrelease_calendar_markets
    • Addedresolution_audit
    • Addedresolution_diff
    • Changedvariant2 fields changed
      • changedOutput schema / properties / variant / properties / transcript_consequences / items / properties / hgvsp / type
        Previous value: -"string"New value: +[
        +  "string",
        +  "null"
        +]
      • changedOutput schema / properties / variant / properties / transcript_consequences / items / properties / is_canonical / type
        Previous value: -"boolean"New value: +[
        +  "boolean",
        +  "null"
        +]
  3. 1 tool update
    • Changedbet_research2 fields changed
      • changedInput schema / examples
        Previous value: -[
        -  {
        -    "market": "when-will-bitcoin-hit-150k"
        -  },
        -  {
        -    "market": "https://polymarket.com/event/when-will-bitcoin-hit-150k"
        -  }
        -]New value: +[
        +  {
        +    "market": "will-kristi-noem-win-the-2028-republican-presidential-nomination"
        +  },
        +  {
        +    "market": "https://polymarket.com/event/will-kristi-noem-win-the-2028-republican-presidential-nomination"
        +  }
        +]
      • changedInput schema / properties / market / description
        Previous value: -"Polymarket slug (\"when-will-bitcoin-hit-150k\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k?\"). Dated slugs stop resolving once they settle — Polymarket de-indexes resolved markets — so prefer an undated one."New value: +"Polymarket slug (\"will-kristi-noem-win-the-2028-republican-presidential-nomination\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k?\"). Dated slugs stop resolving once they settle — Polymarket de-indexes resolved markets — so prefer an undated one."
  4. 1 tool update
    • Changedpolymarket_kalshi_spread1 field changed
      • changedInput schema / examples
        Previous value: -[
        -  {
        -    "topic": "fed"
        -  },
        -  {
        -    "topic": "btc"
        -  }
        -]New value: +[
        +  {
        +    "topic": "fed"
        +  },
        +  {
        +    "topic": "btc"
        +  },
        +  {
        +    "topic": "bitcoin"
        +  },
        +  {
        +    "topic": "fed rate decision"
        +  }
        +]
  5. 2 tool updates
    • Changedbet_research2 fields changed
      • changedInput schema / examples
        Previous value: -[
        -  {
        -    "market": "will-bitcoin-reach-100k-in-july-2026"
        -  },
        -  {
        -    "market": "https://polymarket.com/event/will-bitcoin-hit-150k-by-june-30-2026"
        -  }
        -]New value: +[
        +  {
        +    "market": "when-will-bitcoin-hit-150k"
        +  },
        +  {
        +    "market": "https://polymarket.com/event/when-will-bitcoin-hit-150k"
        +  }
        +]
      • changedInput schema / properties / market / description
        Previous value: -"Polymarket slug (\"will-bitcoin-hit-150k-by-june-30-2026\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k by June 30?\")"New value: +"Polymarket slug (\"when-will-bitcoin-hit-150k\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k?\"). Dated slugs stop resolving once they settle — Polymarket de-indexes resolved markets — so prefer an undated one."
    • Changedpolymarket_kalshi_spread1 field changed
      • changedInput schema / properties / topic / description
        Previous value: -"Pre-mapped: fed | btc | cpi | gdp | sp500 | recession | next_pope | next_uk_pm | next_israel_pm | 2028_president"New value: +"Subject to compare. Canonical keys: fed | btc | eth | cpi | gdp | sp500 | recession | next_pope | next_uk_pm | next_israel_pm | 2028_president — but aliases and keywords resolve too (\"bitcoin\", \"fed rate decision\", \"ethereum\", \"inflation\", \"s&p 500\", \"us recession\", \"next pope\", \"2028 election\"). Check resolution.topic_matched_by in the response: \"exact\"/\"alias\" is a curated pairing, \"phrase\"/\"token\" is a keyword guess."

Related MCP Connectors

Related MCP Servers

  • A
    license
    B
    quality
    A
    maintenance
    MCP server that exposes the Open Targets Platform GraphQL API as a set of tools for querying biomedical data such as targets, diseases, drugs, and genetic evidence.
    68
    150 PyPI
    19
    MIT
  • F
    license
    B
    quality
    D
    maintenance
    Enables AI assistants to query genetic variant data, gene constraints, and population genetics information from the gnomAD (Genome Aggregation Database) through its GraphQL API. Supports searching for genes and variants, retrieving constraint scores, analyzing population frequencies, and accessing genomic coverage data.
    9
    10
    -
  • A
    license
    Not graded
    quality
    A
    maintenance
    Federates 13 gene-related MCP backends (gnomAD, GTEx, etc.) behind a single Streamable HTTP endpoint with collision-free namespacing and search-based tool discovery.
    6
    MIT
  • A
    license
    Not graded
    quality
    A
    maintenance
    Look up variant allele frequencies by ancestry, gene loss-of-function constraint, gene variant lists, and sequencing coverage over gnomAD — with ClinVar significance joined in — via MCP.
    370 npm
    1
    Apache 2.0
Try in Browser

Glama MCP Gateway

Add one secure layer between your agents and this server.