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search_open_targets

Search the Open Targets Platform for genes, diseases, or drugs by entering a query term to retrieve associated biological data.

Instructions

Search Open Targets Platform for genes, diseases, or drugs.

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
queryYesSearch term (gene, disease, or drug name)
Behavior2/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

With no annotations, the description must disclose behavioral traits. It does not mention any, such as whether the tool is read-only, if results are paginated, or if it makes external API calls. This lack of transparency could lead to incorrect assumptions.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness4/5

Is the description appropriately sized, front-loaded, and free of redundancy?

The description is a single sentence that is front-loaded and to the point. It is concise, but could be slightly improved by adding a brief note about result format without losing brevity.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness3/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

Given the tool's simplicity (one parameter, no output schema, no annotations), the description covers the basic purpose and parameter. However, it does not describe the output format or any constraints, leaving some ambiguity for an agent to invoke correctly.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema coverage is 100%, so baseline is 3. The description repeats the schema's parameter description exactly ('Search term (gene, disease, or drug name)'), adding no new meaning beyond what the schema already provides.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

The description clearly states the action (Search) and the resource (Open Targets Platform) for specific entities (genes, diseases, or drugs). It distinguishes well from sibling tools that search other databases like AlphaFold or ClinVar.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines3/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

The description implies usage for searching Open Targets, but does not explicitly state when to use this tool versus alternatives like search_ncbi_gene or search_ensembl_gene. No when-not-to-use guidance is provided.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

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