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get_eqtl_data

Fetch expression quantitative trait loci (eQTL) from GTEx for a given SNP and tissue. Optionally filter by gene to focus on specific expression associations.

Instructions

Get expression quantitative trait loci (eQTL) data from GTEx for a SNP and tissue.

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
rsidYesrsID to query
tissueNoGTEx tissue type (e.g., 'Whole_Blood', 'Brain_Cortex')
geneNoOptional gene to filter results
Behavior3/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

No annotations are present, so the description carries full burden. It indicates the tool queries GTEx eQTL data, but does not discuss rate limits, error handling, or authorization needs. The behavior is simple, so a middle score is appropriate.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness5/5

Is the description appropriately sized, front-loaded, and free of redundancy?

Single sentence, no fluff. Clearly communicates the tool's purpose with no wasted words.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness3/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

Given the lack of annotations, output schema, and the tool's moderate complexity (3 params, 1 required), the description is brief. It does not explain the return format or account for edge cases, but it covers the basics.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema description coverage is 100%, and the description minimally adds by mentioning 'SNP and tissue' and 'Optional gene to filter results', but these are already in schema fields. No new meaning beyond schema.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

The description clearly states the action 'Get' and the specific resource 'expression quantitative trait loci (eQTL) data from GTEx' with the required inputs (SNP and tissue), making it distinct from sibling tools like get_variant_info.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines2/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

No guidance is provided on when to use this tool versus alternatives (e.g., get_variant_info, query_gwas_catalog). The description only states what it does, not when it is appropriate.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

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