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query_gwas_catalog

Query the NHGRI-EBI GWAS Catalog to find reported associations for a specific SNP, trait, or gene.

Instructions

Query the NHGRI-EBI GWAS Catalog for previously reported associations for a SNP or trait.

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
rsidNorsID to query (e.g., 'rs12345')
traitNoTrait/disease to search for (e.g., 'diabetes')
geneNoGene name to search for (e.g., 'BRCA1')
Behavior3/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

No annotations are provided, so the description must disclose behavior. It indicates a read operation but omits details like result limits, handling of multiple inputs, or authentication requirements.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness5/5

Is the description appropriately sized, front-loaded, and free of redundancy?

A single, front-loaded sentence of 13 words efficiently communicates the tool's function.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness4/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

For a simple query tool with no output schema, the description sufficiently explains the scope, though it could mention the source database name or results format.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema coverage is 100% with descriptive parameter names and descriptions. The description adds no new info beyond mentioning 'SNP or trait'.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

The description clearly states the verb 'Query' and the specific resource 'NHGRI-EBI GWAS Catalog' for 'previously reported associations', making it distinct from sibling tools like 'get_disease_associations' or 'search_clinvar'.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines4/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

The description implies usage when seeking known GWAS associations for a SNP or trait, providing context but lacking explicit when-not-to-use or alternatives.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

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