ThaleMine: Experimental Interactions
experimental_interactionsRetrieve curated experimental interaction partners for an Arabidopsis locus from ThaleMine, sourced from BioGRID, IntAct, and PSI-MI, with evidence details such as detection method and PubMed IDs.
Instructions
Fetch CURATED EXPERIMENTAL protein/genetic interaction partners for an Arabidopsis locus from ThaleMine (BAR's InterMine instance; free, no key), sourced from BioGRID, IntAct and PSI-MI. Unlike string_interactions (predicted / text-mined, scored) and bar_aiv_interactions (which returns GRN paper references for Arabidopsis, not partner pairs), every partner here carries the actual experimental provenance: detection method (two hybrid, pull down, genetic interference, ...), PSI-MI relationship type, physical vs genetic class, source database, and the PubMed IDs that reported it. ThaleMine emits one row per evidence record, so rows are aggregated to one entry per partner with evidence_count as a crude support signal; partners are ordered by that count. found=false means the gene is real but has no curated interaction on record — a normal outcome; an unknown locus raises a typed NotFoundError. Arabidopsis only (ThaleMine carries genes for taxon 3702; other organisms raise OrganismNotSupported).
Input Schema
| Name | Required | Description | Default |
|---|---|---|---|
| locus | Yes | AGI locus, e.g. AT5G11260 (HY5) | |
| organism | No | Plant organism — accepts canonical slug (arabidopsis_thaliana), scientific or common name, or NCBI taxid. ThaleMine supports Arabidopsis only. | arabidopsis_thaliana |
Output Schema
| Name | Required | Description | Default |
|---|---|---|---|
| found | Yes | True if any curated interaction exists for this locus | |
| locus | Yes | ||
| organism | Yes | Canonical organism slug (Arabidopsis only) | |
| partners | No | Partners ordered by evidence count, descending | |
| truncated | Yes | True if the partner list was capped | |
| source_url | Yes | ThaleMine gene report page | |
| gene_symbol | No | Gene symbol from ThaleMine | |
| partner_count | Yes | Total distinct partners (pre-cap) | |
| evidence_count | Yes | Total evidence records across all partners (pre-cap) — counted over every partner upstream, not only the partners listed here |