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musharna

plant-genomics-mcp

by musharna

Synthesis: Consensus Homologs

consensus_homologs
Read-onlyIdempotent

Identify reliable plant gene homologs by combining UniProt, Gramene, and BLAST evidence, ranking by cross-source agreement.

Instructions

Synthesis: cross-source homology consensus. Resolves UniProt + FASTA sequence, then runs Gramene homology calls and NCBI BLAST in parallel. Dedupes hits by normalized locus token and scores by n_sources * mean_identity — Gramene contributes identity=1.0, BLAST contributes pident/100.

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
locusYes
top_nNo
organismNoPlant organism — accepts canonical slug (arabidopsis_thaliana), scientific or common name, or NCBI taxidarabidopsis_thaliana

Output Schema

TableJSON Schema
NameRequiredDescriptionDefault
toolYesSynthesis tool name, e.g. analyze_locus_synth
inputYesEchoed input arguments
stepsYesPer-backend execution rows
resultNoComposed cross-source result; None if root step failed
elapsed_sYesTotal orchestrator wall time
started_atYesISO 8601 UTC timestamp
Behavior5/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Annotations already declare read-only and idempotent behavior, but the description adds substantial detail: resolving UniProt + FASTA, parallel execution, deduplication by normalized locus token, and the exact scoring formula with per-source identity contributions. This goes well beyond the structured hints.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness5/5

Is the description appropriately sized, front-loaded, and free of redundancy?

The description is concise, front-loaded with the core purpose, and every sentence adds meaningful detail about sources, algorithm, and scoring. No wasted words or redundant repetition of the schema.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness4/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

The tool is complex, and the description covers the pipeline, scoring, and deduplication. The output schema handles return-value documentation. However, it does not mention the role of top_n or possible caveats when sources disagree, leaving a modest completeness gap.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema documentation covers only the organism parameter (33% coverage). The description adds meaning for locus by explaining it is resolved to UniProt + FASTA and used in normalized locus tokens, but it does not explain top_n or clarify how many results are returned. This partial compensation leaves a clear gap.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

The description clearly states a specific purpose: 'cross-source homology consensus' combining Gramene and NCBI BLAST with a defined scoring method. It distinguishes itself from sibling tools like gramene_homologs and blast_sequence by emphasizing the synthesis/deduplication behavior.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines4/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

The description strongly implies when to use this tool: when a cross-source consensus of homology calls is needed rather than a single-source result. It does not explicitly name alternatives or give 'when-not-to-use' guidance, but the synthesis framing provides clear usage context.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

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