Ensembl MCP Server

MIT License

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get_homologs

Identify orthologous and paralogous genes across species using a gene ID and optional target species. Supports JSON or XML output for comparative genomic analysis.

Instructions

Find orthologous and paralogous genes across species

Input Schema

Name	Required	Description
`format`	No	Output format (default: json)
`gene_id`	Yes	Ensembl gene ID
`species`	No	Source species name (default: homo_sapiens)
`target_species`	No	Target species to search (optional)
`type`	No	Homolog type (default: all)

Input Schema (JSON Schema)

{
  "properties": {
    "format": {
      "description": "Output format (default: json)",
      "enum": [
        "json",
        "xml"
      ],
      "type": "string"
    },
    "gene_id": {
      "description": "Ensembl gene ID",
      "type": "string"
    },
    "species": {
      "description": "Source species name (default: homo_sapiens)",
      "type": "string"
    },
    "target_species": {
      "description": "Target species to search (optional)",
      "type": "string"
    },
    "type": {
      "description": "Homolog type (default: all)",
      "enum": [
        "orthologues",
        "paralogues",
        "all"
      ],
      "type": "string"
    }
  },
  "required": [
    "gene_id"
  ],
  "type": "object"
}

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