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batch_sequence_fetch

Retrieve DNA sequences for multiple genomic regions or features from Ensembl in a single request, supporting up to 50 regions with configurable output formats.

Instructions

Fetch sequences for multiple regions or features

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
regionsYesList of regions or feature IDs (max 50)
speciesNoSpecies name (default: homo_sapiens)
formatNoOutput format (default: fasta)

Implementation Reference

  • The handler function for the 'batch_sequence_fetch' tool. It iterates over the provided regions, fetches sequences individually using handleGetSequence, collects results (success or error per region), and returns a batched JSON response.
    private async handleBatchSequenceFetch(args: any) { try { const species = this.getDefaultSpecies(args.species); const format = args.format || 'fasta'; const results = []; for (const region of args.regions) { try { const sequenceResult = await this.handleGetSequence({ region, species, format, }); results.push({ region, success: true, data: JSON.parse(sequenceResult.content[0].text), }); } catch (error) { results.push({ region, success: false, error: error instanceof Error ? error.message : 'Unknown error', }); } } return { content: [ { type: 'text', text: JSON.stringify({ batch_results: results }, null, 2), }, ], }; } catch (error) { return this.handleError(error, 'batch sequence fetch'); } }
  • src/index.ts:876-879 (registration)
    Registration in the tool dispatch switch statement within CallToolRequestSchema handler. Maps the tool name to its handler method.
    case 'batch_gene_lookup': return this.handleBatchGeneLookup(args); case 'batch_sequence_fetch': return this.handleBatchSequenceFetch(args);
  • src/index.ts:815-826 (registration)
    Tool registration in the ListToolsRequestSchema response, including name, description, and input schema.
    name: 'batch_sequence_fetch', description: 'Fetch sequences for multiple regions or features', inputSchema: { type: 'object', properties: { regions: { type: 'array', items: { type: 'string' }, description: 'List of regions or feature IDs (max 50)', minItems: 1, maxItems: 50 }, species: { type: 'string', description: 'Species name (default: homo_sapiens)' }, format: { type: 'string', enum: ['json', 'fasta'], description: 'Output format (default: fasta)' }, }, required: ['regions'], }, },
  • Type guard function for validating input arguments to batch_sequence_fetch, matching the inputSchema.
    const isValidBatchSequenceArgs = ( args: any ): args is { regions: string[]; species?: string; format?: string } => { return ( typeof args === 'object' && args !== null && Array.isArray(args.regions) && args.regions.length > 0 && args.regions.length <= 50 && args.regions.every((r: any) => typeof r === 'string' && r.length > 0) && (args.species === undefined || typeof args.species === 'string') && (args.format === undefined || ['json', 'fasta'].includes(args.format)) ); };

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