uniprot_target_dossier
Aggregates UniProt entry data into a structured dossier for drug-discovery workflows, covering identity, function, structure, drug targets, and disease associations to guide subsequent deep dives.
Instructions
One-call comprehensive characterisation of a UniProt entry, structured for drug-discovery / clinical workflows. Composes nine views over the same entry plus one FASTA fetch (so two upstream network calls, not nine):
Identity · Function · Sequence chemistry · Structural evidence (PDB count + best-resolution + AlphaFold model id + InterPro count) · Drug-target context (ChEMBL ids, DrugBank count) · Disease associations (with MIM IDs) · Variants count · Functional annotations (top GO MF, subcellular, ECO diversity) · Cross-references summary
For per-residue pLDDT confidence call uniprot_get_alphafold_confidence
separately. For full disease detail call
uniprot_get_disease_associations. The dossier is the entry-
level summary that decides which deeper tools are worth calling.
Input Schema
| Name | Required | Description | Default |
|---|---|---|---|
| accession | Yes | UniProt accession, e.g. 'P04637' (human TP53) or 'P38398' (human BRCA1). Both reviewed (Swiss-Prot) and unreviewed (TrEMBL) accessions are accepted; case-sensitive. | |
| response_format | No | 'markdown' (default) for a human-readable report with a provenance footer, or 'json' for a machine-parseable structured payload with the same data. Any other value is rejected. | markdown |
Output Schema
| Name | Required | Description | Default |
|---|---|---|---|
| result | Yes |