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uniprot_resolve_chembl

Read-only

Resolve ChEMBL drug-target cross-references for a given UniProt accession. Returns ChEMBL target IDs with EBI viewer links, or empty if no bioactivity data exists.

Instructions

Resolve ChEMBL drug-target cross-references for a UniProt entry. Returns the ChEMBL target IDs with EBI viewer links — empty if the protein has no documented bioactivity data in ChEMBL.

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
accessionYes
response_formatNomarkdown

Output Schema

TableJSON Schema
NameRequiredDescriptionDefault
resultYes
Behavior4/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Annotations already declare readOnlyHint and openWorldHint. The description adds valuable behavioral context: returns ChEMBL target IDs with EBI viewer links and notes empty result when no bioactivity data. No contradiction with annotations.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness5/5

Is the description appropriately sized, front-loaded, and free of redundancy?

Two sentences, front-loaded with purpose and succinctly covering behavior. No unnecessary words. Ideal conciseness.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness3/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

With an output schema present, the description covers the basic functionality and edge case. However, it omits parameter explanations, leaving the agent to infer details. Adequate for a simple tool but not fully complete.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters2/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema description coverage is 0%, and the description does not explain the parameters. 'accession' is implied but not described as UniProt accession; 'response_format' is not mentioned at all. The description fails to compensate for the lack of schema descriptions.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

The description clearly states the tool resolves ChEMBL drug-target cross-references for a UniProt entry, using specific verbs and resource. It distinguishes from sibling resolve_* tools by its target database.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines3/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

The description implies usage when needing ChEMBL cross-references but does not provide explicit guidance on when to use this tool over alternatives or when not to use it. No exclusion or comparison with siblings.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

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