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Search Files Across Experiments

encode_search_files
Read-onlyIdempotent

Search for specific file types across all ENCODE experiments using combined filters like file format, assay type, organism, and organ to locate genomic data files efficiently.

Instructions

Search files across ALL experiments with combined experiment + file filters.

This is powerful for finding specific file types across many experiments.

Examples:

  • All BED files from human pancreas ChIP-seq: file_format="bed", assay_title="Histone ChIP-seq", organ="pancreas"

  • FASTQs from mouse liver RNA-seq: file_format="fastq", assay_title="RNA-seq", organ="liver", organism="Mus musculus"

  • All IDR peak files for H3K27me3: output_type="IDR thresholded peaks", target="H3K27me3"

  • BigWig signal tracks from ATAC-seq on brain tissue: file_format="bigWig", assay_title="ATAC-seq", organ="brain", biosample_type="tissue"

WHEN TO USE: Use to find specific file types across ALL experiments. More powerful than encode_list_files for cross-experiment file discovery. RELATED TOOLS: encode_list_files, encode_batch_download, encode_get_file_info

Args: file_format: File format ("fastq", "bam", "bed", "bigWig", etc.) file_type: Specific file type ("bed narrowPeak", "bed broadPeak", etc.) output_type: Output type ("reads", "peaks", "signal", etc.) output_category: Output category ("raw data", "alignment", "signal", "annotation") assembly: Genome assembly ("GRCh38", "hg19", "mm10") assay_title: Filter by assay type of parent experiment organism: Filter by organism of parent experiment organ: Filter by organ of parent experiment biosample_type: Filter by biosample type ("tissue", "cell line", etc.) target: Filter by ChIP/CUT&RUN target status: File status (default: "released") preferred_default: If True, only default/recommended files search_term: Free text search limit: Max results (default 25) offset: Skip first N results (pagination)

Returns: JSON with file results, total count, and pagination info.

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
file_formatNo
file_typeNo
output_typeNo
output_categoryNo
assemblyNo
assay_titleNo
organismNo
organNo
biosample_typeNo
targetNo
statusNoreleased
preferred_defaultNo
search_termNo
limitNo
offsetNo

Output Schema

TableJSON Schema
NameRequiredDescriptionDefault
resultYes
Behavior4/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

The annotations already provide important behavioral hints (readOnlyHint, openWorldHint, idempotentHint, destructiveHint). The description adds valuable context beyond these annotations by explaining this is a 'powerful' tool for 'cross-experiment file discovery,' providing concrete usage examples, and mentioning pagination behavior in the Returns section. It doesn't contradict annotations.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness4/5

Is the description appropriately sized, front-loaded, and free of redundancy?

The description is well-structured with clear sections: purpose statement, power explanation, examples, usage guidelines, related tools, parameters, and returns. While comprehensive, every section earns its place by adding value. The examples are particularly efficient at conveying complex usage patterns. Minor points deducted for some redundancy between the initial statement and 'WHEN TO USE' section.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness5/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

Given the tool's complexity (15 parameters, cross-experiment searching), the description provides excellent context. It explains the tool's power and scope, provides multiple concrete examples, gives explicit usage guidance, lists related tools, documents all parameters, and describes the return format. With annotations covering safety/behavioral aspects and an output schema existing, the description is complete for this search tool.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters4/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

With 0% schema description coverage (only titles, no descriptions), the description carries the full burden of explaining parameters. It provides an 'Args' section that lists all 15 parameters with brief explanations and includes concrete examples showing how multiple parameters can be combined in real queries (e.g., 'file_format="bed", assay_title="Histone ChIP-seq", organ="pancreas"'). This adds significant semantic value beyond the bare schema.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

The description clearly states the tool's purpose with specific verbs ('search files across ALL experiments') and distinguishes it from sibling tools by explicitly mentioning 'More powerful than encode_list_files for cross-experiment file discovery.' It provides both the action (search) and scope (across all experiments with combined filters).

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines5/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

The description includes an explicit 'WHEN TO USE' section that states 'Use to find specific file types across ALL experiments' and provides a direct comparison to encode_list_files. It also lists related tools (encode_list_files, encode_batch_download, encode_get_file_info) to guide the agent toward alternatives when appropriate.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

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