get_top_expressed_genes

Identify the most highly expressed genes in a specific human tissue using GTEx data, with options to filter mitochondrial genes and customize sorting parameters.

Instructions

Get top expressed genes in a specific tissue

Input Schema

Name	Required	Description	Default
`datasetId`	No	GTEx dataset ID (default: gtex_v8)	gtex_v8
`filterMtGenes`	No	Filter out mitochondrial genes (default: true)
`sortBy`	No	Sort criteria (default: median)	median
`sortDirection`	No	Sort direction (default: desc)	desc
`tissueSiteDetailId`	Yes	Tissue site detail ID (e.g., Muscle_Skeletal, Brain_Cortex)

Input Schema (JSON Schema)

{
  "properties": {
    "datasetId": {
      "default": "gtex_v8",
      "description": "GTEx dataset ID (default: gtex_v8)",
      "type": "string"
    },
    "filterMtGenes": {
      "default": true,
      "description": "Filter out mitochondrial genes (default: true)",
      "type": "boolean"
    },
    "sortBy": {
      "default": "median",
      "description": "Sort criteria (default: median)",
      "enum": [
        "median",
        "mean"
      ],
      "type": "string"
    },
    "sortDirection": {
      "default": "desc",
      "description": "Sort direction (default: desc)",
      "enum": [
        "asc",
        "desc"
      ],
      "type": "string"
    },
    "tissueSiteDetailId": {
      "description": "Tissue site detail ID (e.g., Muscle_Skeletal, Brain_Cortex)",
      "type": "string"
    }
  },
  "required": [
    "tissueSiteDetailId"
  ],
  "type": "object"
}

GTEx MCP Server

get_top_expressed_genes

Instructions

Input Schema

Input Schema (JSON Schema)

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