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GTEx MCP Server

Server Configuration

Describes the environment variables required to run the server.

NameRequiredDescriptionDefault

No arguments

Schema

Prompts

Interactive templates invoked by user choice

NameDescription

No prompts

Resources

Contextual data attached and managed by the client

NameDescription

No resources

Tools

Functions exposed to the LLM to take actions

NameDescription
get_gene_expression

Get gene expression data across tissues for a specific gene

get_median_gene_expression

Get median gene expression levels across tissues

get_top_expressed_genes

Get top expressed genes in a specific tissue

get_tissue_specific_genes

Get genes with tissue-specific expression patterns

get_clustered_expression

Get clustered gene expression data for visualization

calculate_expression_correlation

Calculate expression correlation between genes across tissues

get_differential_expression

Get differential gene expression between tissue groups

get_eqtl_genes

Get genes with eQTL associations for a genomic region

get_single_tissue_eqtls

Get single-tissue eQTL results for a gene

calculate_dynamic_eqtl

Calculate dynamic eQTL effects across tissues

get_multi_tissue_eqtls

Get multi-tissue eQTL meta-analysis results

get_sqtl_results

Get splicing QTL (sQTL) results for a gene

analyze_ld_structure

Analyze linkage disequilibrium structure around eQTL variants

search_genes

Search for genes by symbol, name, or description

get_gene_info

Get detailed information about a specific gene

get_variants

Get genetic variants in a genomic region

get_tissue_info

Get information about GTEx tissues and sample counts

get_sample_info

Get GTEx sample metadata and demographics

get_subject_phenotypes

Get subject phenotype data and demographics

validate_gene_id

Validate and normalize gene identifiers

validate_variant_id

Validate variant identifiers and genomic coordinates

get_dataset_info

Get information about available GTEx datasets

search_transcripts

Search for gene transcripts and isoforms

get_gene_ontology

Get Gene Ontology annotations for a gene

convert_coordinates

Convert between different genomic coordinate systems

MCP directory API

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