GTEx MCP Server

calculate_dynamic_eqtl

Compute dynamic eQTL effects for gene-SNP pairs across multiple tissues using GTEx data to identify tissue-specific genetic regulation of gene expression.

Instructions

Calculate dynamic eQTL effects across tissues

Input Schema

Name	Required	Description	Default
`datasetId`	No	GTEx dataset ID (default: gtex_v8)	gtex_v8
`gencodeId`	Yes	GENCODE gene ID (e.g., ENSG00000223972.5)
`snpId`	Yes	SNP ID (rs number or variant ID)
`tissueSiteDetailIds`	Yes	Array of tissue site detail IDs to compare

Input Schema (JSON Schema)

{
  "properties": {
    "datasetId": {
      "default": "gtex_v8",
      "description": "GTEx dataset ID (default: gtex_v8)",
      "type": "string"
    },
    "gencodeId": {
      "description": "GENCODE gene ID (e.g., ENSG00000223972.5)",
      "type": "string"
    },
    "snpId": {
      "description": "SNP ID (rs number or variant ID)",
      "type": "string"
    },
    "tissueSiteDetailIds": {
      "description": "Array of tissue site detail IDs to compare",
      "items": {
        "type": "string"
      },
      "type": "array"
    }
  },
  "required": [
    "gencodeId",
    "snpId",
    "tissueSiteDetailIds"
  ],
  "type": "object"
}

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