analyze_ld_structure
Analyze linkage disequilibrium patterns around eQTL variants to understand genetic associations and co-inheritance in specific genomic regions.
Instructions
Analyze linkage disequilibrium structure around eQTL variants
Input Schema
| Name | Required | Description | Default |
|---|---|---|---|
| chr | Yes | Chromosome (e.g., chr1, chr2, chrX) | |
| population | No | Population for LD analysis (default: EUR) | EUR |
| position | Yes | Genomic position (1-based) | |
| windowSize | No | Window size around position (default: 100000) |
Input Schema (JSON Schema)
{
"properties": {
"chr": {
"description": "Chromosome (e.g., chr1, chr2, chrX)",
"type": "string"
},
"population": {
"default": "EUR",
"description": "Population for LD analysis (default: EUR)",
"enum": [
"EUR",
"AFR",
"AMR",
"EAS",
"SAS"
],
"type": "string"
},
"position": {
"description": "Genomic position (1-based)",
"type": "integer"
},
"windowSize": {
"default": 100000,
"description": "Window size around position (default: 100000)",
"type": "integer"
}
},
"required": [
"chr",
"position"
],
"type": "object"
}