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Augmented-Nature

Unofficial PubChem MCP Server

search_by_target

Identify compounds tested against specific biological targets like genes, proteins, or pathways. Filter results by activity type and customize the number of records retrieved.

Instructions

Find compounds tested against a specific biological target

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
activity_typeNoType of activity (e.g., IC50, EC50, Ki)
max_recordsNoMaximum number of results (1-1000, default: 100)
targetYesTarget name (gene, protein, or pathway)

Implementation Reference

  • Handler function that executes the tool logic for 'search_by_target'. Currently a placeholder that returns a 'not yet implemented' message.
    private async handleSearchByTarget(args: any) { return { content: [{ type: 'text', text: JSON.stringify({ message: 'Target search not yet implemented', args }, null, 2) }] }; }
  • Input schema defining parameters for the 'search_by_target' tool: target (required), activity_type, max_records.
    inputSchema: { type: 'object', properties: { target: { type: 'string', description: 'Target name (gene, protein, or pathway)' }, activity_type: { type: 'string', description: 'Type of activity (e.g., IC50, EC50, Ki)' }, max_records: { type: 'number', description: 'Maximum number of results (1-1000, default: 100)', minimum: 1, maximum: 1000 }, }, required: ['target'], },
  • src/index.ts:612-624 (registration)
    Tool registration object passed to server.setTools(), defining name, description, and schema for 'search_by_target'.
    { name: 'search_by_target', description: 'Find compounds tested against a specific biological target', inputSchema: { type: 'object', properties: { target: { type: 'string', description: 'Target name (gene, protein, or pathway)' }, activity_type: { type: 'string', description: 'Type of activity (e.g., IC50, EC50, Ki)' }, max_records: { type: 'number', description: 'Maximum number of results (1-1000, default: 100)', minimum: 1, maximum: 1000 }, }, required: ['target'], }, },
  • src/index.ts:786-787 (registration)
    Switch case in request handler that dispatches calls to the 'search_by_target' handler function.
    case 'search_by_target': return await this.handleSearchByTarget(args);

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