ensembl_homology
Find orthologues or paralogues across species via Ensembl Compara. Input a gene symbol or ID to get homologs with percent identity, optionally filtered by species or taxon.
Instructions
Find orthologues or paralogues of a gene across species (Ensembl Compara) — the cross-species gene mapping source in biomcp.
Returns target stable IDs, species, taxonomy level, and percent identity, sorted by identity. Accepts an HGNC symbol or Ensembl gene ID; scope to one species with target_species ('mouse') or target_taxon (10090). Use it for conservation questions ('is this gene conserved?', 'what is the mouse orthologue of BRAF?').
Input Schema
| Name | Required | Description | Default |
|---|---|---|---|
| gene | Yes | Gene symbol (BRAF) or Ensembl gene ID (ENSG00000157764) | |
| type | No | Homology type to fetch | orthologues |
| limit | No | Maximum homologies to return (sorted by percent identity) | |
| species | No | Source species — 'human' (default), 'mouse', … | human |
| target_taxon | No | Restrict results to a taxon ID, e.g. 10090 (Mus musculus) | |
| target_species | No | Restrict results to one species, e.g. 'mouse' |