bc_get_panglaodb_marker_genes

Retrieve marker genes from the PanglaoDB dataset by specifying species, sensitivity, specificity, organ, cell type, or gene symbol filters for precise biological analysis.

Instructions

Retrieves marker genes from the PanglaoDB dataset based on specified filters.

Args: species: The species ('Hs' for Human or 'Mm' for Mouse). min_sensitivity: Minimum sensitivity score (0-1). min_specificity: Minimum specificity score (0-1). organ: Filter by organ name (case-insensitive). cell_type: Filter by cell type name (case-insensitive). gene_symbol: Filter by gene symbol (case-insensitive).

Returns: A dictionary containing a list of matching marker gene records or an error message.

Input Schema

Name	Required	Description
`cell_type`	No	Filter by cell type (e.g., 'Smooth muscle cells', 'T cells'). Case-insensitive.
`gene_symbol`	No	Filter by gene symbol (e.g., 'MAFB', 'SYNPO'). Case-insensitive.
`min_sensitivity`	No	Minimum sensitivity score (0-1). Applied to species-specific column.
`min_specificity`	No	Minimum specificity score (0-1). Applied to species-specific column.
`organ`	No	Filter by organ (e.g., 'Brain', 'Lung'). Case-insensitive.
`species`	Yes	The species ('Hs' for Human or 'Mm' for Mouse)

Input Schema (JSON Schema)

{
  "properties": {
    "cell_type": {
      "anyOf": [
        {
          "type": "string"
        },
        {
          "type": "null"
        }
      ],
      "default": null,
      "description": "Filter by cell type (e.g., 'Smooth muscle cells', 'T cells'). Case-insensitive.",
      "title": "Cell Type"
    },
    "gene_symbol": {
      "anyOf": [
        {
          "type": "string"
        },
        {
          "type": "null"
        }
      ],
      "default": null,
      "description": "Filter by gene symbol (e.g., 'MAFB', 'SYNPO'). Case-insensitive.",
      "title": "Gene Symbol"
    },
    "min_sensitivity": {
      "anyOf": [
        {
          "maximum": 1,
          "minimum": 0,
          "type": "number"
        },
        {
          "type": "null"
        }
      ],
      "default": null,
      "description": "Minimum sensitivity score (0-1). Applied to species-specific column.",
      "title": "Min Sensitivity"
    },
    "min_specificity": {
      "anyOf": [
        {
          "maximum": 1,
          "minimum": 0,
          "type": "number"
        },
        {
          "type": "null"
        }
      ],
      "default": null,
      "description": "Minimum specificity score (0-1). Applied to species-specific column.",
      "title": "Min Specificity"
    },
    "organ": {
      "anyOf": [
        {
          "type": "string"
        },
        {
          "type": "null"
        }
      ],
      "default": null,
      "description": "Filter by organ (e.g., 'Brain', 'Lung'). Case-insensitive.",
      "title": "Organ"
    },
    "species": {
      "description": "The species ('Hs' for Human or 'Mm' for Mouse)",
      "title": "Species",
      "type": "string"
    }
  },
  "required": [
    "species"
  ],
  "type": "object"
}

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