methods-mcp
methods-mcp
Adaptadores de métodos de Bioconductor para el sustrato md-lab. Cada adaptador envuelve un método (limma, fgsea, DESeq2, …) como una herramienta MCP respaldada por un pequeño contenedor FastAPI-in-Docker que ejecuta R a través de rpy2.
Reemplaza al playbase-mcp planeado originalmente. OmicsPlayground tiene licencia CC BY-NC-ND (no apta para uso comercial); envolvemos Bioconductor directamente. Ver md-lab/NOTES.md §3.
Estado
Esqueleto v0.1.0. Solo limma está estructurado, y su contenedor aún no existe; las llamadas a la herramienta devuelven status: "container_unavailable" hasta que el contenedor esté disponible. Este repositorio existe para probar el patrón de adaptador de extremo a extremo.
Related MCP server: dynamic-mcp
Arquitectura
Cowork / Codex / Jupyter
↓ MCP tool call: limma(intensity_parquet=..., contrast=..., ...)
methods-mcp (FastMCP, this repo)
↓ HTTP POST /run
method-limma container (FastAPI + rpy2, separate repo)
↓ rpy2
R: limma::eBayes(limma::lmFit(...))
↑ result parquet
methods-mcp
↑ {results_parquet, summary, methods_sentence, provenance}
CallerCada adaptador tiene cuatro archivos: manifest.yaml, adapter.py, Dockerfile, README.md. Ver src/methods_mcp/adapters/limma/ para conocer la estructura de referencia.
Lista de envío principal (S2–S3)
Método | Estado | Contenedor |
limma | esqueleto | no construido |
fgsea | — | — |
fisher_ora | — | — |
DESeq2 | — | — |
WGCNA | — | — |
glmnet + RF | — | — |
survival (coxph) | — | — |
sva + ComBat | — | — |
La célula única (Seurat, monocle3, Azimuth) también está en el alcance de la v0.1 según las respuestas de la entrevista §Q4.
Instalación
pip install -e ".[dev]"
pytest
# run server
python mcp_server.py # stdio transport
python mcp_server_http.py # HTTP transport, port 7102Registro de la comunidad
Una vez que el patrón se consolide, cualquier colaborador puede enviar un paquete de adaptador: manifest.yaml + adapter.py + Dockerfile + README.md. md-lab methods install <name> realiza la obtención desde el índice YAML central en webwebb56/md-methods-registry. Instalación mediante obtención al estilo Homebrew, no resolución automática al estilo npm.
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Maintenance
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