methods-mcp
methods-mcp
用于 md-lab 底层的 Bioconductor 方法适配器。每个适配器都将一种方法(limma、fgsea、DESeq2 等)封装为 MCP 工具,并由一个通过 rpy2 运行 R 的小型 FastAPI-in-Docker 容器提供支持。
取代了原计划的 playbase-mcp。OmicsPlayground 采用 CC BY-NC-ND 协议(商业使用不安全);我们直接封装 Bioconductor。参见 md-lab/NOTES.md 第 3 节。
状态
v0.1.0 骨架。 目前仅搭建了 limma 的框架,且其容器尚未构建——在容器发布之前,工具调用将返回 status: "container_unavailable"。此仓库旨在端到端验证适配器模式。
Related MCP server: dynamic-mcp
架构
Cowork / Codex / Jupyter
↓ MCP tool call: limma(intensity_parquet=..., contrast=..., ...)
methods-mcp (FastMCP, this repo)
↓ HTTP POST /run
method-limma container (FastAPI + rpy2, separate repo)
↓ rpy2
R: limma::eBayes(limma::lmFit(...))
↑ result parquet
methods-mcp
↑ {results_parquet, summary, methods_sentence, provenance}
Caller每个适配器包含四个文件:manifest.yaml、adapter.py、Dockerfile、README.md。参考形状请参见 src/methods_mcp/adapters/limma/。
核心发布列表 (W2–W3)
方法 | 状态 | 容器 |
limma | 骨架 | 未构建 |
fgsea | — | — |
fisher_ora | — | — |
DESeq2 | — | — |
WGCNA | — | — |
glmnet + RF | — | — |
survival (coxph) | — | — |
sva + ComBat | — | — |
根据 面试回答 §Q4,单细胞分析(Seurat、monocle3、Azimuth)也在 v0.1 的范围内。
安装
pip install -e ".[dev]"
pytest
# run server
python mcp_server.py # stdio transport
python mcp_server_http.py # HTTP transport, port 7102社区注册表
一旦该模式稳定,任何贡献者都可以发布适配器包:manifest.yaml + adapter.py + Dockerfile + README.md。md-lab methods install <name> 将从 webwebb56/md-methods-registry 中的中央 YAML 索引获取。采用类似 Homebrew 的获取式安装,而非 npm 式的自动解析。
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