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smaniches
by smaniches

Map Disease Drug Landscape

map_disease_drug_landscape
Read-onlyIdempotent

Map the complete therapeutic landscape for a disease, including approved drugs, pipeline agents, top targets, and investability summary, using MONDO disease ID.

Instructions

Map the complete therapeutic landscape for a disease.

Returns approved drugs, pipeline agents, top druggable targets, and an investability summary for a given MONDO disease.

Combines Open Targets evidence with ChEMBL drug indications and MONDO disease hierarchy to produce a comprehensive landscape report used in business development, competitive intelligence, and R&D portfolio decisions.

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
paramsYes

Output Schema

TableJSON Schema
NameRequiredDescriptionDefault

No arguments

Behavior4/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Annotations already provide readOnlyHint, idempotentHint, openWorldHint. The description adds that it combines Open Targets, ChEMBL, and MONDO, enriching understanding of data sources and behavior. No contradictions.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness5/5

Is the description appropriately sized, front-loaded, and free of redundancy?

Three well-structured sentences: purpose, output, use cases. No unnecessary words, front-loaded information.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness4/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

Given the presence of an output schema, the description adequately covers the tool's function and use cases. It could mention limitations or more precise data freshness, but overall it is complete for an agent to decide usage.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters2/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema description coverage is 0%, meaning the only parameter description is 'MONDO disease ID.' The tool description does not elaborate on the parameter beyond that, failing to add value beyond the schema for a single parameter.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

The description clearly states the tool maps the complete therapeutic landscape for a disease, specifying outputs (approved drugs, pipeline agents, druggable targets, investability summary) and input (MONDO disease ID). This distinguishes it from siblings like get_disease_targets.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines4/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

The description mentions the tool is 'used in business development, competitive intelligence, and R&D portfolio decisions,' providing context. However, it lacks explicit guidance on when not to use it or comparison to alternatives.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

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