Analyze Structural Confidence (pLDDT + PAE)
analyze_structural_confidenceEvaluate AlphaFold model reliability with pLDDT and PAE scores to identify trustworthy regions, domain boundaries, and druggability potential for target assessment.
Instructions
Analyze AlphaFold structural confidence using pLDDT and PAE.
Returns a structural reliability summary (not a per-residue profile):
pLDDT: the model's mean confidence (AlphaFold DB
globalMetricValue) plus a coarse confidence tierPAE (predicted aligned error): mean and max inter-residue uncertainty and PAE-derived domain boundaries
Druggability pre-screen: an ordered-fraction estimate and a structure-based-drug-design suitability flag
Input Schema
| Name | Required | Description | Default |
|---|---|---|---|
| params | Yes |
Output Schema
| Name | Required | Description | Default |
|---|---|---|---|
No arguments | |||