Analyze Structural Confidence (pLDDT + PAE)
analyze_structural_confidenceAssess the structural reliability of a protein by analyzing AlphaFold pLDDT and PAE metrics. Returns confidence tiers, domain boundaries, and a druggability pre-screen.
Instructions
Analyze AlphaFold structural confidence using pLDDT and PAE.
Returns a structural reliability summary (not a per-residue profile):
pLDDT: the model's mean confidence (AlphaFold DB
globalMetricValue) plus a coarse confidence tierPAE (predicted aligned error): mean and max inter-residue uncertainty and PAE-derived domain boundaries
Druggability pre-screen: an ordered-fraction estimate and a structure-based-drug-design suitability flag
Input Schema
| Name | Required | Description | Default |
|---|---|---|---|
| params | Yes |
Output Schema
| Name | Required | Description | Default |
|---|---|---|---|
No arguments | |||