Analyze Structural Confidence (pLDDT + PAE)
analyze_structural_confidenceEvaluate the structural confidence of an AlphaFold model using pLDDT and PAE metrics to determine reliability, domain boundaries, and druggability suitability.
Instructions
Analyze AlphaFold structural confidence using pLDDT and PAE.
Returns a structural reliability summary (not a per-residue profile):
pLDDT: the model's mean confidence (AlphaFold DB
globalMetricValue) plus a coarse confidence tierPAE (predicted aligned error): mean and max inter-residue uncertainty and PAE-derived domain boundaries
Druggability pre-screen: an ordered-fraction estimate and a structure-based-drug-design suitability flag
Input Schema
| Name | Required | Description | Default |
|---|---|---|---|
| params | Yes |
Output Schema
| Name | Required | Description | Default |
|---|---|---|---|
No arguments | |||