gnomAD MCP Server

Instructions

Implementation Reference

• server.py:228-247 (handler)

  The `search_for_variants` tool is defined here as an MCP tool, using `run_query_with_metadata` to fetch data.

  def search_for_variants(
      dataset: str,
      reference_genome: str,
      query: str
  ) -> dict:
      """
      [gnomAD API] Search for variants (v2/v3/v4)
      Args:
          dataset (str): gnomAD dataset ID (gnomad_r4/gnomad_r3/gnomad_r2_1)
          reference_genome (str): Reference genome (GRCh37 or GRCh38)
          query (str): Search string (variant_id)
      Returns:
          dict: search results (variant_id)
      """
      variables = {
          'dataset': dataset,
          'reference_genome': reference_genome,
          'query': query,
      }
      return run_query_with_metadata('variant_search', variables)