ChatSpatial
Server Configuration
Describes the environment variables required to run the server.
| Name | Required | Description | Default |
|---|---|---|---|
No arguments | |||
Instructions
Guidance the server publishes about itself, which clients place ahead of the tool catalog so the model reads it before choosing anything.
This server publishes no instructions, or was last inspected before Glama recorded them.
Capabilities
Features and capabilities supported by this server
Protocol revision2025-11-25
| Capability | Details |
|---|---|
| tools | {
"listChanged": false
} |
| prompts | {
"listChanged": false
} |
| resources | {
"subscribe": false,
"listChanged": false
} |
Tools
Functions exposed to the LLM to take actions
| Name | Description |
|---|---|
| load_dataA | Load spatial transcriptomics data with comprehensive metadata profile. |
| preprocess_dataA | Run QC, filtering, normalization, and highly variable gene selection. |
| compute_embeddingsB | Compute dimensionality reduction (PCA, UMAP), clustering, and neighbor graphs. |
| visualize_dataB | Visualize spatial transcriptomics data. Set plot_type and subtype in params; see VisualizationParameters schema for all options. |
| annotate_cell_typesA | Annotate cell types in spatial transcriptomics data. |
| analyze_spatial_statisticsA | Analyze spatial statistics and autocorrelation patterns. |
| find_markersC | Find differentially expressed genes between groups. |
| compare_conditionsA | Compare experimental conditions using pseudobulk differential expression (DESeq2). |
| analyze_cnvA | Analyze copy number variations (CNVs) in spatial transcriptomics data. |
| analyze_velocity_dataB | Analyze RNA velocity to understand cellular dynamics. Requires 'spliced' and 'unspliced' layers. |
| analyze_trajectory_dataC | Infer cellular trajectories and pseudotime ordering. |
| integrate_samplesB | Integrate multiple spatial transcriptomics samples into a unified dataset. |
| deconvolve_dataC | Deconvolve spatial spots to estimate cell type proportions. |
| identify_spatial_domainsC | Identify spatial domains and tissue architecture. |
| analyze_cell_communicationB | Analyze cell-cell communication and ligand-receptor interaction patterns. |
| analyze_enrichmentC | Perform gene set enrichment analysis. |
| find_spatial_genesC | Identify spatially variable genes. |
| register_spatial_dataC | Register/align spatial transcriptomics data across sections |
| export_dataA | Export dataset to disk for external script access. |
| reload_dataA | Reload dataset from disk after external script modifications. |
Prompts
Interactive templates invoked by user choice
| Name | Description |
|---|---|
No prompts | |
Resources
Contextual data attached and managed by the client
| Name | Description |
|---|---|
No resources | |
TDQS
Scored across 20 tools
Most tools target clearly distinct stages of spatial transcriptomics analysis, such as loading, preprocessing, embeddings, domain detection, deconvolution, and communication. A few pairs have overlapping scope—find_markers versus compare_conditions for differential expression, and analyze_spatial_statistics versus find_spatial_genes for spatial gene statistics—but descriptions and parameter differences help distinguish them.
All tool names use snake_case and follow a verb_noun or verb_object convention (load_data, preprocess_data, find_markers, analyze_cnv, export_data). Verb choices vary appropriately by operation, with no inconsistent casing or mixed naming styles.
The suite has 20 tools, slightly above the ideal 3-15 range, but this matches a comprehensive spatial transcriptomics workflow with many distinct analysis stages. Each tool earns its place, though the surface is somewhat heavy for an MCP server.
The tools cover the full analysis lifecycle: loading, preprocessing, embeddings, visualization, spatial statistics/domains/genes, deconvolution, annotation, cell communication, CNV, velocity, trajectory, and export/reload. Minor lifecycle gaps such as listing or deleting datasets prevent a perfect completeness score.