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90,516 servers. Updated
20 Best GitHub MCP Servers: compared and ranked, September 2026Ranked from 1,676 matching servers on stars, growth, downloads and maintenance. Updated .

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  • F
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    Leverages large language models to analyze users' WeGene genetic testing reports, providing access to report data via custom URI schemes and enabling profile and report management through OAuth authentication and API utilization.
    4
    4
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    An MCP server that connects AI agents to the PEPTOMA open DeSci peptide research platform, enabling peptide sequence analysis, feed search, and peer-review annotations.
    6 npm
    MIT
  • A
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    C
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    MCP server for querying the GWAS Catalog (EBI/NHGRI), a curated catalog of genome-wide association studies. It enables AI agents to search and retrieve study data via natural language or direct tool calls.
    2 npm
    MIT
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    Enables querying of the Monarch Initiative biomedical knowledge graph for genes, diseases, phenotypes, and their associations through natural language or direct tool calls.
    2 npm
    MIT
  • A
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    This server provides access to InterPro protein family, domain, and functional-site classification data from EBI. It allows querying protein annotations through natural language or direct tool calls.
    4 npm
    MIT
  • A
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    A
    maintenance
    Federates 13 gene-related MCP backends (gnomAD, GTEx, etc.) behind a single Streamable HTTP endpoint with collision-free namespacing and search-based tool discovery.
    6
    MIT
  • A
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    Not graded
    quality
    B
    maintenance
    Bioinformatics MCP for genomic variant interpretation, gene-disease evidence and literature. Folklore 1.5.0 adds read-only ClinGen gene-to-disease and disease-to-gene lookups alongside GRCh38 germline variant interpretation and biomedical literature. Seven tools; public information only; qualified professional review required.
    1
    Apache 2.0
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    Provides MCP tool adapters for Bioconductor methods like limma, DESeq2, and fgsea, enabling statistical analysis of omics data through containerized R execution. It serves as a bridge between MCP clients and bioinformatics tools for reproducible research workflows.
    Apache 2.0
  • A
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    C
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    Resolves free-text condition and disease strings — trial-registry condition fields, drug-label indications, hand-typed wording — onto the Mondo Disease Ontology, returning the best term id and label along with a trustworthy match-quality label (exact label/synonym, broader, narrower, fuzzy, or no-match) plus cross-ontology xrefs. Optionally expands a resolved term to all of its descendant ids for building subtype-inclusive registry filters.
    52 npm
    MIT
  • A
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    quality
    A
    maintenance
    Search UniProtKB by protein function, fetch curated records, map IDs across databases, and pull reference proteomes, taxonomy, and sequences via MCP. Supports both STDIO and Streamable HTTP transports.
    61 npm
    2
    Apache 2.0
  • F
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    B
    maintenance
    A terminal-based bioinformatics CLI chat tool that integrates Ensembl VEP, NCBI ClinVar, an MCP server layer, and OpenRouter's NVIDIA Nemotron 3 Ultra model to provide variant consequence and clinical significance lookups with clear summaries in a Rich-powered CLI.
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