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pipeworx-io

mcp-gwas-catalog

by pipeworx-io

mcp-gwas-catalog

GWAS Catalog (EBI/NHGRI) MCP — curated catalog of genome-wide association studies.

Part of Pipeworx — an MCP gateway connecting AI agents to 1476+ live data sources.

Tools

Tool

Description

get_snp

GWAS Catalog: look up a single-nucleotide polymorphism (SNP) by rsID. Returns functional class, chromosome/region locations, and mapped genes (with up/downstream + distance). Keyless, from EBI/NHGRI.

snp_associations

GWAS Catalog: get trait/disease associations for a SNP (rsID) — risk allele, p-value, odds ratio per copy, beta/effect size, and risk allele frequency. Keyless, from EBI/NHGRI.

studies_by_trait

GWAS Catalog: find genome-wide association studies for a disease/trait (EFO trait, e.g. "asthma" or "type 2 diabetes"). Returns accession, PubMed ID, title, journal, date, sample size. Keyless, from EBI/NHGRI.

Related MCP server: gwas-mcp

Quick Start

Add to your MCP client (Claude Desktop, Cursor, Windsurf, etc.):

{
  "mcpServers": {
    "gwas-catalog": {
      "url": "https://gateway.pipeworx.io/gwas-catalog/mcp"
    }
  }
}

What this endpoint actually serves

tools/list at https://gateway.pipeworx.io/gwas-catalog/mcp returns the tools in the table above plus the shared Pipeworx meta-toolsask_pipeworx, discover_tools, search_within, remember/recall and the rest of the gateway-wide set. So the tool count you see is larger than this table: a single-pack endpoint currently lists roughly 30 shared tools alongside the pack's own. The connection's initialize response states its exact scope, and is the authoritative answer for a given day.

This is deliberate, not multiplexing by accident. The meta-tools are what let a scoped connection answer a question this pack does not cover — via ask_pipeworx, which routes across the whole catalog — without you adding a second MCP server. There is currently no way to mount a pack endpoint without them; if the extra schemas cost you more context than the routing is worth, connect to the full gateway once rather than to several pack endpoints.

Or connect to the full Pipeworx gateway to get every pack's tools listed directly, instead of just this one's:

{
  "mcpServers": {
    "pipeworx": {
      "url": "https://gateway.pipeworx.io/mcp"
    }
  }
}

Both URLs reach the same gateway and the same 1476+ data sources. The only difference is which pack's tools are listed directly; ask_pipeworx reaches all of them from either one.

Using with ask_pipeworx

Instead of calling tools directly, you can ask questions in plain English — this works on the pack endpoint above as well as on the full gateway:

ask_pipeworx({ question: "your question about Gwas Catalog data" })

The gateway picks the right tool and fills the arguments automatically.

More

License

MIT

Tool Schema Changelog

Recent tool additions, removals, and schema changes observed during successful MCP inspections. Dates show when Glama detected each change.

No tool schema history has been recorded yet.

Resources

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Looking for Admin?

If you are the server author, to access and configure the admin panel.

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