BioMCP

# How To: Predict Effects BioMCP can request functional-impact predictions through the variant `predict` section. ## Requirements - Set `ALPHAGENOME_API_KEY`. - Prefer a resolvable genomic variant identifier. ## Example ```bash export ALPHAGENOME_API_KEY="..." biomcp get variant "chr7:g.140453136A>T" predict ``` ## Alternate input ```bash biomcp get variant "BRAF V600E" predict ``` ## Validation behavior BioMCP validates identifiers and dates before expensive network work. If a variant cannot be resolved to a supported prediction path, an explicit error or warning is returned. ## Practical guidance - Use prediction output as one signal, not a final interpretation. - Pair predictions with variant annotations and literature context.