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berntpopp
by berntpopp

Get Disease Ancestors

get_disease_ancestors
Read-onlyIdempotent

Retrieve all transitive ancestors (broader diseases) of an Orphanet disorder using a precomputed closure, with pagination for large results.

Instructions

Return all transitive ancestors (broader diseases) of an Orphanet disorder via the precomputed closure, with a pagination block {total, returned, limit, offset, truncated, next_offset}. When truncated, next_commands carries a forward-page step. Use get_disease_classification for only the immediate parents. Signature: get_disease_ancestors(term, limit=, offset=, response_mode=).

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
termYesAn ORPHAcode (ORPHA:166024 or 166024), a disease label/synonym, or an external xref CURIE that resolves to a single Orphanet term.
limitNoMax rows returned (default 200).
offsetNoRows to skip for forward paging (default 0).
response_modeNoVerbosity: minimal|compact|standard|full (default compact).compact

Output Schema

TableJSON Schema
NameRequiredDescriptionDefault
successNo
_metaNo
error_codeNo
messageNo
retryableNo
recovery_actionNo
fieldNo
allowed_valuesNo
hintNo
candidatesNo
orpha_codeNo
nameNo
totalNo
returnedNo
limitNo
offsetNo
next_offsetNo
truncatedNo
ancestorsNo
Behavior4/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Annotations already indicate read-only, idempotent, open-world. Description adds pagination behavior (truncated, next_offset) and the response block shape. No contradictions.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness5/5

Is the description appropriately sized, front-loaded, and free of redundancy?

Two sentences: first states core purpose and pagination format, second gives usage alternative and signature. No wasted words.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness4/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

Covers purpose, parameter signature, pagination, and sibling differentiation. Output schema exists so return values need not be described. Minor gap: no explicit mention of what an empty result looks like.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema covers all 4 parameters (100% coverage). Description adds a summary of parameter order and pagination block, but does not significantly extend parameter meaning beyond schema.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose5/5

Does the description clearly state what the tool does and how it differs from similar tools?

Clearly states 'Return all transitive ancestors (broader diseases) of an Orphanet disorder' using a specific verb+resource. Distinguishes from sibling get_disease_classification by noting immediate parents vs transitive ancestors.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines5/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

Explicitly directs to use get_disease_classification for immediate parents, providing an alternative. Also explains pagination with truncated and next_offset for forward navigation.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.

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