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unip_ipuipu_acc_09a395ae

Read-only

Retrieve interaction partners for a UniProt accession, including names, antibody roles, PDB structures, and self-interaction status. Adds structural and functional context for protein interactions.

Instructions

Retrieve information on interaction partners for a given UniProt accession, including their names, annotations such as antibody roles, the PDB structures where interactions are observed, and whether the interaction is self-directed. This endpoint provides structural and functional context for protein interactions.

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
uniprot_accessionYesUniProt accession. title: Uniprot Accession description: UniProt accession.

Schema Changelog

Changes observed during successful MCP inspections.

  1. Addedv1.1.10

TDQS

B3.2/5.0
Behavior3/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Annotations already declare readOnlyHint=true, destructiveHint=false, so the safety profile is covered structurally. The description adds genuine content-level context by enumerating what the response contains (partner names, antibody roles, observed PDB structures, self-directed flag), but says nothing about data source, coverage, or limits. Note the annotations' idempotentHint=false, which the description does not explain.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness4/5

Is the description appropriately sized, front-loaded, and free of redundancy?

Two sentences, front-loaded with the core action and resource. The closing sentence ('This endpoint provides structural and functional context') is mild filler that restates value rather than adding information, but overall it is tight.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness4/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

With no output schema, the description usefully enumerates the returned fields, which compensates well for a simple read-only, single-parameter tool. The main gap is the absence of any usage tiering among the many sibling endpoints, which is not essential to calling this tool correctly.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Only one parameter with 100% schema description coverage, so the schema carries the meaning; the description merely restates 'for a given UniProt accession'. Baseline 3 is appropriate since no additional format, validation, or resolution detail is offered beyond the schema.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose4/5

Does the description clearly state what the tool does and how it differs from similar tools?

States a specific verb ('Retrieve') and resource ('interaction partners for a given UniProt accession') and enumerates the returned content (names, antibody-role annotations, PDB structures, self-interaction flag). The purpose is unambiguous, though it never names or contrasts any sibling endpoint in a large family of UniProt/complex tools.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines2/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

The description implies the obvious case (you have a UniProt accession and want its interaction partners) but gives no explicit when-to-use guidance, no preconditions, and no routing to related siblings such as the complex/interface tools. An agent gets no help deciding between this and, say, interface or binding-site endpoints.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.