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by PDBeurope

seq_cuuscu_acc_a66a4f59

Read-only

Retrieve PDBe-KB sequence conservation data for a UniProt accession, including residue-level scores and amino acid probability profiles.

Instructions

Retrieve PDBe-KB sequence conservation data for a UniProt accession. The response provides residue-level conservation scores, per-residue amino acid probability profiles, sequence identifiers, the length of the UniProt sequence, and colors for visualizing main and sub-tracks.

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
uniprot_accessionYesUniProt accession. title: Uniprot Accession description: UniProt accession.

Schema Changelog

Changes observed during successful MCP inspections.

  1. Addedv1.1.10

TDQS

B3.2/5.0
Behavior3/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Annotations already declare readOnlyHint=true and destructiveHint=false, so the read-only safety profile is covered. The description usefully supplements this by detailing what the response contains (conservation scores, probability profiles, identifiers, track colors), but says nothing about pagination, auth, or rate limits – acceptable given annotation coverage.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness4/5

Is the description appropriately sized, front-loaded, and free of redundancy?

Two sentences, front-loaded with the action and resource before enumerating the response fields. The response enumeration is slightly list-like but every clause conveys distinct returned data, so it earns its place.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness4/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

There is no output schema, so the description correctly carries the burden of describing the return value and does so concretely. With a single fully-documented parameter and a clear return summary, an agent has enough to call it correctly; only the when-to-use aspect is missing.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

Schema description coverage is 100% and there is only one required parameter, so the schema already documents it fully. The phrase 'for a UniProt accession' adds no format or syntax detail beyond what the schema states, so the baseline of 3 applies.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose4/5

Does the description clearly state what the tool does and how it differs from similar tools?

States a specific verb ('Retrieve') and a specific resource ('PDBe-KB sequence conservation data') scoped to a UniProt accession, which is distinguishable from sibling endpoints covering variation, binding sites, or structure. It does not, however, explicitly name or differentiate itself from any sibling tool by name.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines2/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

The description says what the tool returns but gives no guidance on when to use it versus alternatives such as unip_var or other per-accession endpoints, nor any prerequisites or exclusions. Usage context is left entirely to inference.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.