Skip to main content
Glama
PDBeurope

PDBe MCP Servers

Official
by PDBeurope

unip_giruiru_acc_66c74d5c

Read-only

Retrieve interface residue details for a UniProt accession, including amino acid sequences and total sequence length, to analyze protein interaction sites.

Instructions

Retrieve detailed information on interface residues for a given UniProt accession, including the amino acid sequence for polymeric entities and the total sequence length. The response provides the type of data included and an array of residue-level details, with information such as the starting position in a processed protein sequence when applicable. This endpoint enables analysis of residues involved in protein interfaces, offering sequence context alongside structural and functional annotations.

Input Schema

TableJSON Schema
NameRequiredDescriptionDefault
uniprot_accessionYesUniProt accession. title: Uniprot Accession description: UniProt accession.

Schema Changelog

Changes observed during successful MCP inspections.

  1. Addedv1.1.10

TDQS

B3.1/5.0
Behavior3/5

Does the description disclose side effects, auth requirements, rate limits, or destructive behavior?

Annotations already declare readOnlyHint=true and destructiveHint=false, so safety is covered. The description does add some payload context (residue-level array, sequence length, starting position in a processed sequence), which is genuinely useful because no output schema exists, but it omits any access, rate-limit, or not-found behavior. The idempotentHint=false on a pure read is unexplained.

Agents need to know what a tool does to the world before calling it. Descriptions should go beyond structured annotations to explain consequences.

Conciseness3/5

Is the description appropriately sized, front-loaded, and free of redundancy?

The verb+resource is front-loaded, which is good, but the text is padded with redundant clauses ('offering sequence context alongside structural and functional annotations') and describes the response in two overlapping sentences. It could be roughly half its length without losing meaning.

Shorter descriptions cost fewer tokens and are easier for agents to parse. Every sentence should earn its place.

Completeness3/5

Given the tool's complexity, does the description cover enough for an agent to succeed on first attempt?

With one simple parameter, high schema coverage, and no output schema, the description does carry some of the return-value burden and partially fulfills it by describing the residue array and sequence length. However, the description of the payload is vague and does not let an agent predict the response shape precisely.

Complex tools with many parameters or behaviors need more documentation. Simple tools need less. This dimension scales expectations accordingly.

Parameters3/5

Does the description clarify parameter syntax, constraints, interactions, or defaults beyond what the schema provides?

There is a single parameter with 100% schema description coverage, so the schema baseline is 3. The description adds nothing about the accession format or scope (e.g., canonical vs isoform) beyond what the schema already states.

Input schemas describe structure but not intent. Descriptions should explain non-obvious parameter relationships and valid value ranges.

Purpose4/5

Does the description clearly state what the tool does and how it differs from similar tools?

The description states a specific verb and resource: retrieving interface-residue details for a given UniProt accession, which is unambiguous about what is fetched. It does not, however, distinguish this tool from closely related siblings such as to iface_res_ent_interfaces_id_entity_id or ent_iface_res_ent_iface_res_id, so an agent must infer the selection criteria.

Agents choose between tools based on descriptions. A clear purpose with a specific verb and resource helps agents select the right tool.

Usage Guidelines2/5

Does the description explain when to use this tool, when not to, or what alternatives exist?

There is no explicit when-to-use guidance, no exclusions, and no named alternatives despite many overlapping siblings (entity-based interface residue tools, sequence tools). The only hint is the trailing 'enables analysis of residues involved in protein interfaces,' which is a purpose statement, not routing advice.

Agents often have multiple tools that could apply. Explicit usage guidance like "use X instead of Y when Z" prevents misuse.