"Using Claude to Check the Current Weather Without an API Key" matching MCP servers:

Enables AI agents to query Human Phenotype Ontology clinical phenotype terms, navigate term hierarchies, and retrieve gene-disease and disease-phenotype annotations through keyless MCP tools.

Enables language models to search biomedical literature, fetch sequences, and follow links across Entrez databases through eleven read-only tools wrapping the nine NCBI Entrez E-utilities. It handles URL building, pacing, redirects, response caps, and API-key redaction so queries can be answered without a browser or scraping.

Enables MCP clients to annotate and classify single human genetic variants in any notation, returning an auditable points-based ACMG verdict with its criteria, gnomAD frequencies, in-silico predictors, ClinVar data, and per-transcript consequences. It is read-only, requires no account or API key, and keeps answers compact while linking back to the source.

An MCP server that gives Claude access to NCBI Datasets v2 — search genome assembly metadata, retrieve taxonomy records, and download data packages without leaving your conversation.

An MCP server that provides tools for searching and fetching protein data from the UniProt database using the unipressed library.

Enables variant annotation and effect prediction using the Ensembl VEP API, with support for batch and single queries.

Parses MS-DIAL binary lipidomics outputs and runs standard analyses server-side, returning compact summaries so an LLM can drive full lipidomics analysis without exposing raw matrices.

Allows to retrieve information about an AnnData object via MCP using the read_lazy function from anndata.

An MCP server that enables single-cell RNA sequencing analysis through natural language, supporting data processing, visualization, and analysis tasks without requiring coding knowledge.

Enables AI agents to search, filter, download files, and generate reports from the IGVF Data Portal using natural language commands.

An MCP server that enables AI assistants to generate, score, and analyze DNA sequences using the evo2 genomic foundation model. It supports multiple execution modes including local GPU, SLURM clusters, and the Nvidia NIM cloud API for tasks like variant effect prediction and sequence embedding.

An MCP server that exposes the KEGG REST API — pathways, genes, compounds, reactions, enzymes, diseases, drugs, modules, orthology, glycans, and BRITE hierarchies, with cross-database linking. Provides 34 tools and 8 resource templates.

Enables querying gene expression experiments, brain region structure ontologies, and in-situ hybridization datasets from the Allen Institute's Brain Atlas public API.

An MCP server for running local LLMs using llama-cpp-python, with built-in tools for generating drug-like molecule SMILES.

Enables AI agents to query the fission yeast PomBase database for gene summaries, GO annotations, phenotypes, orthologs, domains, and interactions via structured API calls.

Enables querying and retrieving bacterial and viral genomic data, features, antimicrobial resistance, and epitopes from the BV-BRC API using natural language.

Connects PyMOL to Claude AI through the Model Context Protocol, allowing for conversational structural biology and molecular visualization through natural language commands.

This server provides agents with access to key data across UniProt, RCSB PDB, and ChEMBL archives. It enables the completion of complex biochemical and drug discovery tasks by offering structured tool endpoints.

Lets Claude and ChatGPT open and drive a Spacewalk 3D chromatin viewer alongside the conversation.

Enables querying the Human Protein Atlas data using natural language or direct MCP tools, with keyless access via the Pipeworx gateway.

Enables AI agents to browse the Gene Ontology through the EBI QuickGO API, including keyword search for GO terms, retrieval of a term's name, aspect, definition and synonyms by id, and listing the GO annotations tied to a UniProt accession. Runs keyless over HTTP or as a local stdio server, with an optional gateway route that lets plain-English questions be answered without choosing tools manually.

Folklore MCP 1.7.0 provides ACMG/AMP germline variant classification, gene profiles, ClinGen disease associations and scientific literature. Eleven tools. Free Streamable HTTP; no account or API key required.

An MCP server for the gget bioinformatics library that enables AI assistants to perform complex genomics queries, including gene sequence retrieval, BLAST alignments, and protein structure predictions.

Validates the physical and chemical plausibility of ligand–protein docking poses using the PoseBusters tool.

A public, read-only MCP server and REST API that connects AI agents to Bioconductor package build, check and propagation state, release and download data, dependency and ops activity, plus searchable infrastructure documentation. Every answer is linked to the public upstream source it came from, with results trimmed to the relevant failing sections or capped lists.

Enables Claude and other MCP clients to run fast, exactly scored similarity and substructure searches over a local PubChem fingerprint index, pull live PubChem records (identifiers, synonyms, GHS, bioassays) with cited sources, and compute offline RDKit descriptors, med-chem alerts and highlighted structure drawings — all without API rate limits.

An MCP server that enables language models to fetch protein information from the UniProt database, including protein details, sequences, functions, and structures.

Enables AI agents to search roughly 150 million digitized natural-history museum specimen records (plants, animals, fossils) from US collections, filtered by taxonomy and locality, and to retrieve the full normalized record for any single specimen by its uuid. It also returns taxonomic or geographic specimen counts grouped by a chosen field, optionally narrowed by the same filters, with no API key required.

Enables LLMs to run rule-based molecular interaction simulations using the Kappa language through the Kappybara package. Returns simulation results as CSV data for analysis of biochemical systems and molecular binding dynamics.

Enables on-demand querying of live NASA POWER weather anomalies and NCBI Pathogen Detection genomic antimicrobial-resistance data for causal analysis.