anndata-mcp
Click on "Install Server".
Wait a few minutes for the server to deploy. Once ready, it will show a "Started" state.
In the chat, type
@followed by the MCP server name and your instructions, e.g., "@anndata-mcpshow me the summary of the AnnData object at /data/sample.h5ad"
That's it! The server will respond to your query, and you can continue using it as needed.
Here is a step-by-step guide with screenshots.
AnnData MCP
Allows to retrieve information about an AnnData object via MCP using the read_lazy function from anndata.
Getting started
Please refer to the documentation, in particular, the API documentation.
You can also find the project on BioContextAI, the community-hub for biomedical MCP servers: anndata-mcp on BioContextAI.
Related MCP server: Scanpy-MCP
Installation
You need to have Python 3.11 or newer installed on your system. If you don't have Python installed, we recommend installing uv.
There are several alternative options to install anndata-mcp:
Use
uvxto run it immediately:
uvx anndata-mcpInclude it in one of various clients that supports the
mcp.jsonstandard, please use:
{
"mcpServers": {
"anndata-mcp": {
"command": "uvx",
"args": ["anndata-mcp"]
}
}
}Install it through
pip:
pip install --user anndata-mcpInstall the latest development version:
pip install git+https://github.com/biocontext-ai/anndata-mcp.git@mainContact
If you found a bug, please use the issue tracker.
Citation
If this MCP server is useful to your research, please cite the BioContextAI and the anndata publications:
@article{BioContext_AI_Kuehl_Schaub_2025,
title={BioContextAI is a community hub for agentic biomedical systems},
url={http://dx.doi.org/10.1038/s41587-025-02900-9},
urldate = {2025-11-06},
doi={10.1038/s41587-025-02900-9},
year = {2025},
month = nov,
journal={Nature Biotechnology},
publisher={Springer Science and Business Media LLC},
author={Kuehl, Malte and Schaub, Darius P. and Carli, Francesco and Heumos, Lukas and Hellmig, Malte and Fernández-Zapata, Camila and Kaiser, Nico and Schaul, Jonathan and Kulaga, Anton and Usanov, Nikolay and Koutrouli, Mikaela and Ergen, Can and Palla, Giovanni and Krebs, Christian F. and Panzer, Ulf and Bonn, Stefan and Lobentanzer, Sebastian and Saez-Rodriguez, Julio and Puelles, Victor G.},
year={2025},
month=nov,
language={en},
}@article{Virshup2024,
title = {anndata: Access and store annotated data
matrices},
volume = {9},
ISSN = {2475-9066},
url = {http://dx.doi.org/10.21105/joss.04371},
DOI = {10.21105/joss.04371},
number = {101},
journal = {Journal of Open Source Software},
publisher = {The Open Journal},
author = {Virshup, Isaac and Rybakov, Sergei and Theis, Fabian J. and Angerer, Philipp and Wolf, F. Alexander},
year = {2024},
month = sep,
pages = {4371}
}This server cannot be installed
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