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  • F
    license
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    maintenance
    Control PyMOL from Cursor via natural language. Enables describing molecular structures and styles in plain language to execute PyMOL commands through XML-RPC.
    1
    -
  • A
    license
    A
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    maintenance
    Enables AI-assisted molecular biology experiment design with tools for qPCR primer design, cloning strategy optimization, TaqMan probe design, and multiplex compatibility analysis.
    6
    1
    MIT
  • A
    license
    A
    quality
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    Enables AI assistants to rapidly gather and synthesize structural, chemical, conservation, and literature data about protein binding pockets for drug-target triage. Useful as a reconnaissance step before computational binder design.
    8
    1
    MIT
  • A
    license
    A
    quality
    C
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    Enables MCP clients to discover and call typed tools for protein backbone design, sequence design, complex folding, and binder design via BioNeMo NIMs, with a deterministic simulator by default and optional live routing.
    5
    Apache 2.0
  • A
    license
    A
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    Enables bioinformatics analysis through natural language conversations with Claude Desktop, automatically generating and executing Python scripts to produce HTML reports and visualizations.
    3
    16 npm
    9
    MIT
  • A
    license
    C
    quality
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    maintenance
    Enables workflow management and Docker image building for Bio-OS platform. Supports WDL workflow submission, validation, and monitoring, along with Docker image building and status tracking for bioinformatics workflows.
    22
    5
    MIT
  • A
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    quality
    C
    maintenance
    Enables AI agents to search public cancer genomics studies (TCGA, CPTAC, MSK, and more), fetch full details for individual studies, resolve gene symbols to Entrez ids, and list cancer types. Works keylessly against open cBioPortal data over a hosted MCP endpoint, a local stdio server, or plain HTTP.
    92 npm
    MIT
  • A
    license
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    quality
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    maintenance
    Enables molecular generation, optimization, and analysis through NVIDIA MolMIM API. Supports generating drug-like molecules with desired properties, extracting molecular embeddings, and exploring chemical space around seed molecules.
    1
    MIT
  • A
    license
    Not graded
    quality
    B
    maintenance
    Exposes 25 stdio-based tools for SnapGene-style DNA work, letting agents inspect plasmids, find restriction sites, digest, clone, run PCR, design primers, mutate sequences, auto-annotate features, verify sequencing reads and find CRISPR guides. All file access is sandboxed to a configurable root directory and every operation is available both as a CLI command with JSON output and as an MCP tool.
    MIT
  • A
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    Not graded
    quality
    C
    maintenance
    Enables read-only and preview MCP workflows for GenBank sequence management, primer design, and visualization, with optional write access for importing new records and saving design results.
    MIT
  • A
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    Not graded
    quality
    C
    maintenance
    Enables Claude, Cursor, or any MCP client to query public Drosophila connectome datasets and run in-silico experiments on them locally, with every answer carrying built-in controls, uncertainty, and provenance. Currently exposes dataset listing with licence, citation, download size, and locally cached level details.
    Apache 2.0
  • A
    license
    Not graded
    quality
    B
    maintenance
    Exposes over 100 deterministic medical research engines to any MCP-capable agent, covering statistical tests, survival analysis, bioinformatics pipelines, primer/sequence design, modeling, and PubMed literature search. Every response is computed with real algorithms and tagged with an engine_status of real, unavailable, or error, so agents never receive fabricated numbers.
    MIT
  • A
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    Not graded
    quality
    C
    maintenance
    Enables AI agents to browse the Gene Ontology through the EBI QuickGO API, including keyword search for GO terms, retrieval of a term's name, aspect, definition and synonyms by id, and listing the GO annotations tied to a UniProt accession. Runs keyless over HTTP or as a local stdio server, with an optional gateway route that lets plain-English questions be answered without choosing tools manually.
    304 npm
    MIT
  • A
    license
    Not graded
    quality
    B
    maintenance
    Enables installing, configuring, and running modular MCP servers for biology, bioinformatics, and bioimaging tasks, including local image analysis, ImageJ/Fiji bridging, and LLM-based agent workflows.
    1
    MIT
  • A
    license
    Not graded
    quality
    C
    maintenance
    MCP server for biological protein design, folding, and affinity prediction using Refua tools, with optional support for ADMET, clinical simulation, preclinical planning, wet-lab automation, and more.
    MIT
  • A
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    Not graded
    quality
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    maintenance
    Enables AI assistants to perform genomic variant analysis using OakVar, including running annotation pipelines, managing 200+ annotator modules, querying variant databases, and generating reports in various formats.
    MIT
  • A
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    Not graded
    quality
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    maintenance
    MCP server for Ketcher chemical structure editor integration, enabling SMILES/MOL/InChI conversion, image generation, molecular property calculation, and validation.
    MIT
  • F
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    Not graded
    quality
    C
    maintenance
    Enables RNA structure analysis, sequence evaluation, and inverse design using geometric deep learning models. Supports both quick computational analysis and long-running batch processing for generating RNA sequences that fold into target structures.
    -
  • F
    license
    Not graded
    quality
    D
    maintenance
    Enables Claude Code to interact with a TACC or SLURM HPC cluster for bioinformatics pipelines, allowing job management, log reading, file browsing, remote script execution, and job submission through natural language.
    -
  • F
    license
    Not graded
    quality
    C
    maintenance
    Enables protein modeling and design using the Rosetta suite via Docker, including structure refinement, mutation stability analysis, docking, and loop modeling through natural language commands.
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  • A
    license
    A
    quality
    B
    maintenance
    An MCP server that grounds protein research in the UniProt SPARQL endpoint, providing tools for querying proteins, sequences, variants, diseases, and more via intent-named tools and raw SPARQL.
    15
    MIT
  • A
    license
    A
    quality
    B
    maintenance
    Enables language models to search biomedical literature, fetch sequences, and follow links across Entrez databases through eleven read-only tools wrapping the nine NCBI Entrez E-utilities. It handles URL building, pacing, redirects, response caps, and API-key redaction so queries can be answered without a browser or scraping.
    11
    MIT
  • A
    license
    A
    quality
    C
    maintenance
    Enables AI assistants to search ImmPort immunology studies and subjects, read study data and assay results, look up controlled vocabularies and the data model, and find study files. Supports study comparison, release history lookups, and guided workflows for cross-study analysis.
    9
    37 PyPI
    MIT
  • A
    license
    A
    quality
    B
    maintenance
    Enables AI agents to retrieve cited pharmacogenomic and gene-variant information, including drug–gene guidance from CPIC/DPWG and rsID lookups, so responses can quote curated sources instead of relying on memory. A local package also lets users read raw DNA files on their own computer without sending the file data to the remote service.
    2
    278 PyPI
    MIT
  • A
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    A
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    maintenance
    Provides direct SQL access to a locally hosted Reactome database, enabling schema discovery, guarded read-only queries, and ergonomic helpers over the full relational schema.
    9
    MIT