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97,619 servers. Updated
20 Best GitHub MCP Servers: compared and ranked, October 2026Ranked from 1,788 matching servers on stars, growth, downloads and maintenance. Updated .

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  • F
    license
    C
    quality
    B
    maintenance
    Exposes the NGS360 bioinformatics platform REST API as MCP tools, enabling AI assistants to manage sequencing runs, projects, workflows, and more through natural language.
    82
    -
  • A
    license
    Not graded
    quality
    B
    maintenance
    Enables AI agents to search public cancer genomics studies (TCGA, CPTAC, MSK, and more), fetch full details for individual studies, resolve gene symbols to Entrez ids, and list cancer types. Works keylessly against open cBioPortal data over a hosted MCP endpoint, a local stdio server, or plain HTTP.
    14 npm
    MIT
  • A
    license
    Not graded
    quality
    B
    maintenance
    Enables searching a manually curated database of stable macromolecular protein complexes by protein or complex name, gene, GO term, or biological process, and fetching individual records by accession to retrieve subunits with UniProt identifiers, biological roles, and stoichiometry. Complements UniProt, IntAct, and STRING, and can be used keyless over a hosted gateway endpoint or run locally over stdio.
    19 npm
    MIT
  • A
    license
    Not graded
    quality
    B
    maintenance
    MCP server for querying the GWAS Catalog (EBI/NHGRI), a curated catalog of genome-wide association studies. It enables AI agents to search and retrieve study data via natural language or direct tool calls.
    37 npm
    MIT
  • A
    license
    Not graded
    quality
    B
    maintenance
    Enables searching and retrieving cancer-genomics projects, cases, and genomic data files — including TCGA, TARGET, and CPTAC — via keyless, open-access metadata tools. Supports filtering by primary site, project, or data category, and can route plain-English questions to the right tool automatically.
    35 npm
    MIT
  • A
    license
    Not graded
    quality
    B
    maintenance
    Enables querying of the Monarch Initiative biomedical knowledge graph for genes, diseases, phenotypes, and their associations through natural language or direct tool calls.
    46 npm
    MIT
  • A
    license
    Not graded
    quality
    D
    maintenance
    Enables AI assistants to create, monitor, and manage computational tasks through GA4GH Task Execution Service (TES) functionality. Provides seamless access to TES-compliant services for executing bioinformatics and scientific computing workflows.
    Apache 2.0
  • A
    license
    Not graded
    quality
    B
    maintenance
    This server provides access to InterPro protein family, domain, and functional-site classification data from EBI. It allows querying protein annotations through natural language or direct tool calls.
    68 npm
    MIT
  • A
    license
    Not graded
    quality
    A
    maintenance
    Federates 13 gene-related MCP backends (gnomAD, GTEx, etc.) behind a single Streamable HTTP endpoint with collision-free namespacing and search-based tool discovery.
    6
    MIT
  • A
    license
    Not graded
    quality
    B
    maintenance
    Enables users to search and retrieve 3D cryo-EM and electron-tomography density maps by keyword or entry ID, returning details such as resolution, structure-determination method, sample, and release date.
    14 npm
    1
    MIT
  • A
    license
    Not graded
    quality
    B
    maintenance
    Enables AI agents to look up molecular interactions from the EBI IntAct database by gene/protein name or UniProt ID, returning detection method, interaction type, organism, PubMed reference, and MI confidence score, along with fast interaction counts. It is keyless and available either through a hosted MCP endpoint, a plain HTTP API, or a local stdio server.
    17 npm
    MIT
  • A
    license
    Not graded
    quality
    B
    maintenance
    Enables AI agents to query Protein Data Bank in Europe (EBI) structural data by 4-character PDB ID, retrieving entry summaries, molecule/entity listings with chain lengths, and SIFTS cross-database mappings to UniProt accessions and residue ranges. Runs as a hosted gateway endpoint or a local stdio server with no authentication required.
    17 npm
    MIT
  • F
    license
    Not graded
    quality
    A
    maintenance
    Provides a collection of MCP servers for computational chemistry tasks including molecular generation and retrosynthesis. Also offers property prediction and molecule pricing capabilities.
    -