get_annotations
Fetch UniProt protein annotations by accession and annotation type, providing detailed residue and region information for analysis.
Instructions
This tool retrieves all annotations for a specified UniProt residue range. It allows querying by the UniProt accession and the annotation type (e.g., MUTAGEN for AlphaMissense).
Arguments
qualifier(str): UniProt accession (e.g.,'Q5VSL9').annotation_type(str): Type of annotation (e.g.,'MUTAGEN'for AlphaMissense).
Example Input:
qualifier:
Q5VSL9annotation_type:
MUTAGEN
Response Structure
The response includes detailed information about the UniProt entry and its associated annotations.
Example Output:
{
"accession": "Q5VSL9",
"id": "STRP1_HUMAN",
"sequence": "MEPAVGGPGPLIVNNKQPQPPPPPPPAAAQPPPGAPRAAAGLLPGGKAREFNRNQRKDSEGYSESPDLEFEYADTDKWAAELSELYSYTEGPEFLMNRKCFEEDFRIHVTDKKWTELDTNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQSWMRYNIFLLLEVGTFNALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHQECEGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRSILGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDDDNSLEGETFPLERDEVMPPPLQHPQTDRLTCPKGLPWAPKVREKDIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEVIVKAISAVLLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVHELPELTAESLEAGDSNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRAHSNPDFLPVDNCLQSVLGQRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ",
"annotation": [
{
"type": "MUTAGEN",
"description": "AM score",
"source_name": "AFDB",
"source_url": "https://alphafold.ebi.ac.uk/files/AF-Q5VSL9-F1-aa-substitutions.csv",
"evidence": "COMPUTATIONAL/PREDICTED",
"residues": [1, 2, 3, ...],
"regions": [
{
"start": 1,
"end": 837,
"annotation_value": [0.3234, 0.3281, ...],
"unit": null
}
]
}
]
}Input Schema
TableJSON Schema
| Name | Required | Description | Default |
|---|---|---|---|
| qualifier | Yes | ||
| output_json | No | ||
| annotation_type | No | MUTAGEN |