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Maftools-MCP

Maftools-MCP exposes R maftools analyses through the Model Context Protocol (MCP). An MCP-compatible client can translate a natural-language request into calls for mutation summaries, oncoplots, cohort comparisons, mutation signatures, clinical enrichment, survival analyses, and copy-number visualization.

The server includes the 59 tools counted in the manuscript, plus the export_r_script validation utility: 60 registered tools in total. See the complete tool reference for inputs, defaults, outputs and underlying R functions. R code is executed through rpy2. ANNOVAR annotation is an optional external workflow; the server's conversion tool consumes annotated multianno files, not unannotated VCFs.

Installation

Download the Maftools-MCP Docker image:

docker pull lin97/maftools-mcp:v.1.1.0

For setup instructions, MCP client configuration, and usage examples, see the Maftools-MCP tutorial.

Related MCP server: Liana-MCP

License

Maftools-MCP code is available under the MIT License. R, maftools, ANNOVAR and other dependencies retain their own licenses. This repository does not grant redistribution rights for third-party datasets or ANNOVAR assets.

Tool Schema Changelog

Recent tool additions, removals, and schema changes observed during successful MCP inspections. Dates show when Glama detected each change.

No tool schema history has been recorded yet.

Maintenance

ActivityMaintained
ResponsivenessNo issues

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