Civic
Server Details
CIViC — Clinical Interpretation of Variants in Cancer.
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- Status
- Unhealthy
- Uptime
- 0.1% over 21 days
- Last Tested
- Transport
- Streamable HTTP
- URL
- Repository
- pipeworx-io/mcp-civic
- GitHub Stars
- 0
- Server Listing
- civic
TDQS
Scored across 40 tools
Many tools are clearly scoped (memory, subscriptions, CIViC, dependency checks), but there is substantial overlap among the Pipeworx meta-tools: ask_pipeworx, ask_pipeworx_beta, ask_pipeworx_grounded, deep_research, validate_claim, entity_profile, recent_changes, and compare_entities all answer data-lookup questions. The prediction-market suite also has heavily overlapping tools (polymarket_edges, polymarket_arbitrage, polymarket_fill_risk, polymarket_edge_tracker, bet_research). Descriptions do a lot to steer selection, so it is not chaotic, but boundaries remain fuzzy.
Names are almost entirely lower snake_case, with clear domain prefixes such as civic_, polymarket_, pipeworx_, and kalshi_. They are not uniformly verb_noun — several are noun phrases like entity_profile, company_facts, civic_assertions, recent_alerts — but the convention is still readable and consistent enough.
40 tools is very heavy for one MCP server and includes duplicate/experimental variants such as ask_pipeworx_beta plus many meta-tools. The set spans several unrelated domains (CIViC cancer variants, prediction markets, generic research, memory, subscriptions, AI visibility), so it feels like a platform gateway rather than a well-scoped server. This exceeds the typical 3–15 tool sweet spot by a wide margin.
The surface is broad and covers most lifecycle needs for its apparent domains: CIViC gene/variant/evidence/assertion lookup, company profiles and facts, prediction-market research and arbitrage, entity resolution, memory, subscriptions, and feedback. Minor gaps exist — e.g. no explicit CIViC disease/therapy enumeration tool and no write/update operations — but for a mostly read-only structured-data gateway, coverage is strong.
Tool Schema Changelog
Recent tool additions, removals, and schema changes observed during successful MCP inspections.
40 tool updates
- First observed
ai_visibility_check - First observed
ask_pipeworx - First observed
ask_pipeworx_beta - First observed
ask_pipeworx_grounded - First observed
bet_research - First observed
civic_assertions - First observed
civic_gene_variants - First observed
civic_search_genes - First observed
civic_variant_evidence - First observed
company_facts - First observed
compare_entities - First observed
deep_research - First observed
discover_tools - First observed
entity_profile - First observed
forget - First observed
generate_llms_txt - First observed
kalshi_weather_edge - First observed
list_subscriptions - First observed
pipeworx_feedback - First observed
pipeworx_trending - First observed
polymarket_arbitrage - First observed
polymarket_edge_tracker - First observed
polymarket_edges - First observed
polymarket_fill_risk - First observed
polymarket_kalshi_spread - First observed
recall - First observed
recent_alerts - First observed
recent_changes - First observed
release_calendar_markets - First observed
remember - First observed
resolution_audit - First observed
resolution_diff - First observed
resolve_entity - First observed
scan_competitor_ai_presence - First observed
scan_dependency - First observed
search_within - First observed
subscribe - First observed
suggest_questions - First observed
unsubscribe - First observed
validate_claim
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Related MCP Servers
- FlicenseNot gradedqualityCmaintenanceEnables querying the CIViC database for clinical interpretations of cancer variants through tools like get_variant_evidence and get_variant_assertions.1-
- AlicenseNot gradedqualityFmaintenanceAn MCP server that enables access to clinical evidence from the CIViC database, allowing users to search across variants, diseases, drugs, and phenotypes to support precision oncology research.64MIT
- FlicenseNot gradedqualityBmaintenanceEnables structured queries and data analysis of cancer genomics information by interfacing with the Clinical Interpretation of Variants in Cancer (CIViC) API. It converts GraphQL responses into queryable SQLite tables for efficient clinical interpretation and natural language interaction.-
- FlicenseAqualityFmaintenanceProvides interpretable variant effect predictions for 4.2 million ClinVar variants using the EVEE API. Enables searching, comparing, and analyzing genetic variants with AI-generated mechanistic interpretations and disruption profiles.618-
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