Cbioportal
Server Details
cBioPortal MCP — cancer genomics portal.
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- Status
- Unhealthy
- Uptime
- 33.8% over 55 days
- Last Tested
- Transport
- Streamable HTTP
- URL
- Repository
- pipeworx-io/mcp-cbioportal
- GitHub Stars
- 0
- Server Listing
- cBioPortal MCP
TDQS
Scored across 40 tools
Multiple tools overlap heavily: ask_pipeworx vs ask_pipeworx_beta vs ask_pipeworx_grounded vs deep_research all serve as question routers; discover_tools vs suggest_questions both aid discovery; the polymarket family (arbitrage, edges, fill_risk, edge_tracker, kalshi_spread) has blurry boundaries; and entity_profile vs company_facts vs compare_entities vs recent_changes vs resolve_entity all touch company data. The verbose descriptions help but an agent must read carefully to pick the right one.
All names use snake_case, which is consistent, but the verb style is mixed: get_gene/get_study/list_cancer_types/search_studies follow verb_noun, while ask_pipeworx, entity_profile, company_facts, deep_research, polymarket_edges, and recent_changes are noun_phrases without a leading verb. Still readable and predictable in separator usage.
40 tools is heavy for any single server, and the surface is dominated by unrelated Pipeworx packs (prediction markets, AI marketing, dependency scanning, memory) rather than the stated cBioPortal domain. The name promises one resource but delivers a large multi-pack gateway.
For a server named Cbioportal, only four tools actually address cancer genomics (list_cancer_types, search_studies, get_study, get_gene). Core cBioPortal operations — mutations, clinical attributes, expression data, sample lists, molecular profiles — are entirely absent, leaving major dead ends for the stated purpose.
Tool Schema Changelog
Recent tool additions, removals, and schema changes observed during successful MCP inspections.
1 tool update
- Changed
release_calendar_markets2 fields changed- added
Output schema / properties / empty_reasonAdded value: +{ + "description": "Present ONLY on a zero-release window: \"no_releases_in_window\". The window was queried and nothing is scheduled — this is an answer, not a failure.", + "type": "string" +} - added
Output schema / properties / hintAdded value: +{ + "description": "Present ONLY on a zero-release window: what to change (usually a wider `hours`).", + "type": "string" +}
7 tool updates
- Changed
ask_pipeworx3 fields changed- added
Input schema / properties / askAdded value: +{ + "description": "Alias for question.", + "type": "string" +} - added
Input schema / properties / messageAdded value: +{ + "description": "Alias for question.", + "type": "string" +} - changed
Input schema / properties / question / descriptionPrevious value: -"Your question or request in natural language. Accepts query, q, prompt, text, input as aliases."New value: +"Your question or request in natural language. Accepts query, q, prompt, text, input, ask, message as aliases."
- Changed
ask_pipeworx_beta3 fields changed- added
Input schema / properties / askAdded value: +{ + "description": "Alias for question.", + "type": "string" +} - added
Input schema / properties / messageAdded value: +{ + "description": "Alias for question.", + "type": "string" +} - changed
Input schema / properties / question / descriptionPrevious value: -"Your question or request in natural language. Accepts query, q, prompt, text, input as aliases."New value: +"Your question or request in natural language. Accepts query, q, prompt, text, input, ask, message as aliases."
- Changed
ask_pipeworx_grounded3 fields changed- added
Input schema / properties / askAdded value: +{ + "description": "Alias for question.", + "type": "string" +} - added
Input schema / properties / messageAdded value: +{ + "description": "Alias for question.", + "type": "string" +} - changed
Input schema / properties / question / descriptionPrevious value: -"Your question in natural language. Accepts query, q, prompt, text, input as aliases."New value: +"Your question in natural language. Accepts query, q, prompt, text, input, ask, message as aliases."
- Changed
deep_research8 fields changed- added
Input schema / properties / askAdded value: +{ + "description": "Alias for question.", + "type": "string" +} - added
Input schema / properties / inputAdded value: +{ + "description": "Alias for question.", + "type": "string" +} - added
Input schema / properties / messageAdded value: +{ + "description": "Alias for question.", + "type": "string" +} - added
Input schema / properties / promptAdded value: +{ + "description": "Alias for question.", + "type": "string" +} - added
Input schema / properties / qAdded value: +{ + "description": "Alias for question.", + "type": "string" +} - added
Input schema / properties / queryAdded value: +{ + "description": "Alias for question.", + "type": "string" +} - changed
Input schema / properties / question / descriptionPrevious value: -"The research question, in natural language. Broad/multi-part is fine — decomposition is the point."New value: +"The research question, in natural language. Broad/multi-part is fine — decomposition is the point. Accepts query, q, prompt, text, input, ask, message as aliases." - added
Input schema / properties / textAdded value: +{ + "description": "Alias for question.", + "type": "string" +}
- Changed
forget4 fields changed- added
Input schema / properties / kAdded value: +{ + "description": "Alias for key.", + "type": "string" +} - changed
Input schema / properties / key / descriptionPrevious value: -"Memory key to delete"New value: +"Memory key to delete. Accepts name, k, label as aliases." - added
Input schema / properties / labelAdded value: +{ + "description": "Alias for key.", + "type": "string" +} - added
Input schema / properties / nameAdded value: +{ + "description": "Alias for key.", + "type": "string" +}
- Changed
recall4 fields changed- added
Input schema / properties / kAdded value: +{ + "description": "Alias for key.", + "type": "string" +} - changed
Input schema / properties / key / descriptionPrevious value: -"Memory key to retrieve (omit to list all keys)"New value: +"Memory key to retrieve (omit to list all keys). Accepts name, k, label as aliases." - added
Input schema / properties / labelAdded value: +{ + "description": "Alias for key.", + "type": "string" +} - added
Input schema / properties / nameAdded value: +{ + "description": "Alias for key.", + "type": "string" +}
- Changed
remember9 fields changed- added
Input schema / properties / contentAdded value: +{ + "description": "Alias for value.", + "type": "string" +} - added
Input schema / properties / dataAdded value: +{ + "description": "Alias for value.", + "type": "string" +} - added
Input schema / properties / kAdded value: +{ + "description": "Alias for key.", + "type": "string" +} - changed
Input schema / properties / key / descriptionPrevious value: -"Memory key (e.g., \"subject_property\", \"target_ticker\", \"user_preference\")"New value: +"Memory key (e.g., \"subject_property\", \"target_ticker\", \"user_preference\"). Accepts name, k, label as aliases." - added
Input schema / properties / labelAdded value: +{ + "description": "Alias for key.", + "type": "string" +} - added
Input schema / properties / nameAdded value: +{ + "description": "Alias for key.", + "type": "string" +} - added
Input schema / properties / textAdded value: +{ + "description": "Alias for value.", + "type": "string" +} - added
Input schema / properties / vAdded value: +{ + "description": "Alias for value.", + "type": "string" +} - changed
Input schema / properties / value / descriptionPrevious value: -"Value to store (any text — findings, addresses, preferences, notes)"New value: +"Value to store (any text — findings, addresses, preferences, notes). Accepts content, text, data, v as aliases; a non-string value is stored as JSON."
26 tool updates
- Changed
ai_visibility_check1 field changed- added
Input schema / examplesAdded value: +[ + { + "entity": "Tesla" + } +]
- Changed
ask_pipeworx_beta1 field changed- added
Input schema / examplesAdded value: +[ + { + "question": "What is the current US unemployment rate?" + } +]
- Changed
ask_pipeworx_grounded1 field changed- added
Input schema / examplesAdded value: +[ + { + "question": "What was Apple's fiscal 2023 revenue?" + } +]
- Added
company_facts - Changed
compare_entities1 field changed- added
Input schema / examplesAdded value: +[ + { + "type": "company", + "values": [ + "AAPL", + "MSFT" + ] + } +]
- Changed
deep_research1 field changed- added
Input schema / examplesAdded value: +[ + { + "depth": "quick", + "question": "What is the current US unemployment rate and how has it changed over the past year?" + } +]
- Changed
entity_profile1 field changed- added
Input schema / examplesAdded value: +[ + { + "type": "company", + "value": "AAPL" + } +]
- Changed
generate_llms_txt1 field changed- added
Input schema / examplesAdded value: +[ + { + "url": "https://pipeworx.io" + } +]
- Added
kalshi_weather_edge - Changed
pipeworx_feedback1 field changed- added
Input schema / examplesAdded value: +[ + { + "message": "Fleet #2184 smoke test: verifying pipeworx_feedback example call returns non-empty.", + "type": "other" + } +]
- Changed
pipeworx_trending1 field changed- added
Input schema / examplesAdded value: +[ + { + "window": "7d" + } +]
- Changed
polymarket_arbitrage1 field changed- added
Input schema / examplesAdded value: +[ + { + "topic": "Fed rate decision" + } +]
- Changed
polymarket_edge_tracker1 field changed- added
Input schema / examplesAdded value: +[ + { + "days": 14, + "window": "1wk" + } +]
- Changed
polymarket_edges3 fields changed- added
Input schema / examplesAdded value: +[ + { + "limit": 5, + "window": "1wk" + } +] - changed
Input schema / properties / min_edge_pp / descriptionPrevious value: -"Minimum |edge| in percentage points to include (default 0.5). Edge is evaluated NET of slippage."New value: +"Minimum |edge| in percentage points to include (default 0.5). Edge is evaluated NET of slippage and Polymarket's own taker fee." - changed
Input schema / properties / slippage_pp / descriptionPrevious value: -"Assumed execution slippage in percentage points per leg (default 0.3). Subtracted from raw |edge| before ranking and Kelly sizing. Polymarket has zero trading fees as of 2024 but bid/ask + thin depth typically eats 20-50bp per trade. Bump for very thin partitions; drop to 0 if you have a smarter fill model."New value: +"Assumed execution slippage in percentage points per leg (default 0.3), for bid/ask + thin depth cost that a last-trade price does not show. Subtracted from raw |edge| before ranking and Kelly sizing, ON TOP OF Polymarket's own taker fee — which is NOT zero (rate 0.04-0.07 depending on category, read off each market's own published fee schedule; see fees_pp_applied on every row and fees.ts for the full schedule). Bump slippage for very thin partitions; drop to 0 if you have a smarter fill model — the fee still applies regardless."
- Changed
polymarket_fill_risk1 field changed- added
Input schema / examplesAdded value: +[ + { + "market": "will-the-fed-increase-interest-rates-by-25-bps-after-the-december-2026-meeting-20260729232808636", + "side": "buy_yes", + "size_usd": 1000 + } +]
- Changed
recent_changes1 field changed- added
Input schema / examplesAdded value: +[ + { + "since": "30d", + "type": "company", + "value": "AAPL" + } +]
- Added
release_calendar_markets - Changed
remember1 field changed- added
Input schema / examplesAdded value: +[ + { + "key": "target_ticker", + "value": "AAPL" + } +]
- Added
resolution_audit - Added
resolution_diff - Changed
resolve_entity1 field changed- added
Input schema / examplesAdded value: +[ + { + "type": "company", + "value": "AAPL" + } +]
- Changed
scan_competitor_ai_presence1 field changed- added
Input schema / examplesAdded value: +[ + { + "entities": [ + "Pipeworx", + "Zapier" + ] + } +]
- Changed
scan_dependency1 field changed- added
Input schema / examplesAdded value: +[ + { + "package": "left-pad" + } +]
- Changed
search_within1 field changed- added
Input schema / examplesAdded value: +[ + { + "query": "supply-chain risk", + "text": "Apple Inc. reported fiscal 2023 revenue of $383.285 billion, driven by strong iPhone and Services growth. Net income was $96.995 billion. The company faced supply-chain risk in China during the quarter." + } +]
- Changed
suggest_questions1 field changed- added
Input schema / examplesAdded value: +[ + { + "topic": "finance" + } +]
- Changed
validate_claim1 field changed- added
Input schema / examplesAdded value: +[ + { + "claim": "Apple's fiscal 2023 revenue was $383 billion" + } +]
1 tool update
- Changed
bet_research2 fields changed- changed
Input schema / examplesPrevious value: -[ - { - "market": "when-will-bitcoin-hit-150k" - }, - { - "market": "https://polymarket.com/event/when-will-bitcoin-hit-150k" - } -]New value: +[ + { + "market": "will-kristi-noem-win-the-2028-republican-presidential-nomination" + }, + { + "market": "https://polymarket.com/event/will-kristi-noem-win-the-2028-republican-presidential-nomination" + } +] - changed
Input schema / properties / market / descriptionPrevious value: -"Polymarket slug (\"when-will-bitcoin-hit-150k\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k?\"). Dated slugs stop resolving once they settle — Polymarket de-indexes resolved markets — so prefer an undated one."New value: +"Polymarket slug (\"will-kristi-noem-win-the-2028-republican-presidential-nomination\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k?\"). Dated slugs stop resolving once they settle — Polymarket de-indexes resolved markets — so prefer an undated one."
2 tool updates
- Changed
bet_research2 fields changed- changed
Input schema / examplesPrevious value: -[ - { - "market": "will-bitcoin-reach-100k-in-july-2026" - }, - { - "market": "https://polymarket.com/event/will-bitcoin-hit-150k-by-june-30-2026" - } -]New value: +[ + { + "market": "when-will-bitcoin-hit-150k" + }, + { + "market": "https://polymarket.com/event/when-will-bitcoin-hit-150k" + } +] - changed
Input schema / properties / market / descriptionPrevious value: -"Polymarket slug (\"will-bitcoin-hit-150k-by-june-30-2026\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k by June 30?\")"New value: +"Polymarket slug (\"when-will-bitcoin-hit-150k\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k?\"). Dated slugs stop resolving once they settle — Polymarket de-indexes resolved markets — so prefer an undated one."
- Changed
polymarket_kalshi_spread2 fields changed- changed
Input schema / examplesPrevious value: -[ - { - "topic": "fed" - }, - { - "topic": "btc" - } -]New value: +[ + { + "topic": "fed" + }, + { + "topic": "btc" + }, + { + "topic": "bitcoin" + }, + { + "topic": "fed rate decision" + } +] - changed
Input schema / properties / topic / descriptionPrevious value: -"Pre-mapped: fed | btc | cpi | gdp | sp500 | recession | next_pope | next_uk_pm | next_israel_pm | 2028_president"New value: +"Subject to compare. Canonical keys: fed | btc | eth | cpi | gdp | sp500 | recession | next_pope | next_uk_pm | next_israel_pm | 2028_president — but aliases and keywords resolve too (\"bitcoin\", \"fed rate decision\", \"ethereum\", \"inflation\", \"s&p 500\", \"us recession\", \"next pope\", \"2028 election\"). Check resolution.topic_matched_by in the response: \"exact\"/\"alias\" is a curated pairing, \"phrase\"/\"token\" is a keyword guess."
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