Get Position Tolerance
get_position_toleranceRetrieve missense tolerance, Pfam domain membership, and variant evidence for a single protein residue position. Provide transcript ID and residue position.
Instructions
Return one residue's missense tolerance (sw_dn_ds + sliding-window coverage), its Pfam/meta-domain membership, and explicitly scoped variant evidence on a built tolerance landscape. Out-of-range positions raise invalid_input; a not-yet-built landscape raises not_found (request_tolerance_landscape first). Signature: get_position_tolerance(transcript_id=, position=, response_mode=).
Input Schema
| Name | Required | Description | Default |
|---|---|---|---|
| position | Yes | 1-based protein residue position. | |
| response_mode | No | Verbosity: minimal|compact|standard|full (default compact). | compact |
| transcript_id | Yes | A versioned Ensembl transcript id (the .N version suffix is required), e.g. ENST00000269305.4. Resolve a gene symbol with resolve_transcript first. |