Search for medical conditions, diseases, and health problems in ICD-11 (International Classification of Diseases, 11th Revision).

Use this tool to:

• Find ICD-11 codes for diagnoses

• Search for diseases by name or keyword

• Look up conditions in multiple languages

Set language for WHO's official translations — e.g. language: "pt" searches and returns the official Portuguese (pt-BR) ICD-11 labels. Never machine-translated.

Returns matching entities with codes, titles, and relevance scores.

Get detailed information about a specific ICD-11 entity by code or URI.

Use this tool to:

• Get the full definition of a disease

• Retrieve coding notes and exclusions

• Get the official title and synonyms

Provide either an ICD-11 code (e.g., "BA00") or a full foundation URI. Set language for WHO's official translations (e.g. language: "pt" for official Portuguese).

Navigate the ICD-11 hierarchy to find parent or child entities.

Use this tool to:

• Find broader categories (parents) of a condition

• Find specific subtypes (children) of a condition

• Understand the classification structure

Direction 'parents' returns ancestor categories, 'children' returns subcategories.

List all ICD-11 chapters (top-level categories).

Use this tool to:

• Get an overview of ICD-11 structure

• Find which chapter covers a body system or condition type

• Navigate to specific disease categories

ICD-11 has 28 chapters covering all areas of medicine.

Get postcoordination information for an ICD-11 code.

Use this tool to:

• Find available axes for building composite codes

• Check required vs optional postcoordination

• Understand code extension possibilities

Postcoordination allows adding severity, laterality, anatomy, etc.

Search for laboratory tests, clinical observations, and measurements in LOINC (Logical Observation Identifiers Names and Codes).

Use this tool to:

• Find LOINC codes for lab tests (e.g., "glucose", "hemoglobin")

• Search for clinical measurements and vital signs

• Look up diagnostic observations

Returns matching LOINC codes with names, components, and properties.

Get detailed information about a specific LOINC code.

Use this tool to:

• Get the full name and description of a LOINC code

• Find the component, property, timing, and system

• Check the scale type and method

Provide a LOINC number in format "XXXXX-X" (e.g., "2339-0" for Glucose).

Get the list of valid answers for a LOINC questionnaire item.

Use this tool to:

• Find valid response options for survey questions

• Get answer codes for data entry validation

• Look up standardized answer lists

Only applicable to LOINC codes that represent questions with defined answer sets.

Get the structure of a LOINC panel or form.

Use this tool to:

• See all tests included in a panel (e.g., CBC, metabolic panel)

• Get the structure of assessment forms

• Find related observations grouped together

Returns the list of LOINC codes that make up the panel.

Search for drugs in RxNorm (Normalized names for clinical drugs).

Use this tool to:

• Find drug concepts by brand or generic name

• Look up medications for prescribing

• Search for drug formulations

Returns matching drugs with RxCUI identifiers, names, and term types.

Get detailed information about a specific RxNorm concept by RxCUI.

Use this tool to:

• Get the full name and synonyms for a drug

• Check the concept status (active, remapped, etc.)

• View related concepts (ingredients, brands, forms)

Provide an RxCUI (RxNorm Concept Unique Identifier) like "161".

Get active ingredients for a drug by RxCUI.

Use this tool to:

• Find the active ingredients in a medication

• Check for single vs. multiple ingredient products

• Identify the generic components of brand drugs

Returns ingredient RxCUIs and names.

Get therapeutic and pharmacologic classes for a drug.

Use this tool to:

• Find the drug class (e.g., "Beta-blockers", "NSAIDs")

• Identify therapeutic categories

• Look up mechanism of action classifications

Returns class IDs, names, and classification sources.

Map between RxNorm concepts and National Drug Codes (NDC).

Use this tool to:

• Get all NDC codes for a drug (by RxCUI)

• Find the RxCUI for an NDC code

• Cross-reference between coding systems

Provide either an RxCUI to get NDCs, or an NDC to get the RxCUI.

Search for MeSH (Medical Subject Headings) descriptors.

Use this tool to:

• Find MeSH terms for indexing medical literature

• Look up subject headings for PubMed searches

• Find controlled vocabulary terms

Set language to request NLM's official translations where they exist (e.g. language: "pt" for Portuguese labels); content is never machine-translated.

Returns matching descriptors with MeSH IDs and labels.

Get detailed information about a MeSH descriptor by ID.

Use this tool to:

• Get the full definition (scope note) of a MeSH term

• View tree numbers showing hierarchy location

• See related concepts and synonyms

Provide a MeSH Descriptor ID like "D015242" (Ofloxacin). Set language to request NLM's official translations where they exist (e.g. language: "pt").

Get the tree hierarchy location(s) for a MeSH descriptor.

Use this tool to:

• See where a term fits in the MeSH hierarchy

• Understand broader/narrower relationships

• Find related terms in the same branch

MeSH tree numbers show the hierarchical path (e.g., C14.280.647 for Myocardial Infarction).

Get allowed qualifiers (subheadings) for a MeSH descriptor.

Use this tool to:

• Find which qualifiers can be combined with a descriptor

• Build precise MeSH search queries

• Understand aspects that can be specified

Qualifiers refine descriptors (e.g., "Diabetes Mellitus/drug therapy").

Authoritative ICD-10 → ICD-11 mapping using WHO transition tables (release 2025-01, bundled with the server).

Returns the primary 1:1 ICD-11 category for the ICD-10 code plus any alternative ICD-11 candidates that WHO documents (some ICD-10 concepts split into multiple ICD-11 entities). For each mapping, includes the ICD-11 code, title, chapter, and the Foundation URI / Linearization URI for navigating to the full entity definition.

Use this for clinical coding, billing migration, retrospective analysis, and any workflow that needs authoritative mapping rather than text-search candidates. Coverage: 11,243 ICD-10 categories (excludes chapters and blocks like "A00-A09" which aren't used in clinical coding).

Provide a code like "E11" (Type 2 diabetes), "I21" (Acute MI), or "A07.8" (4 alternatives in WHO's table). Both dotted ("A07.8") and undotted ("A078") forms are accepted.

Returns "no mapping" when the code isn't in the WHO category-level table — that's the honest answer rather than a fuzzy search fallback.

This tool looks up a LOINC code in NLM Clinical Tables and returns guidance on where to obtain a LOINC → SNOMED CT mapping. It does not perform the mapping.

Direct LOINC → SNOMED CT mappings are not freely available via API. UMLS Metathesaurus contains the relationships but requires an individual UMLS Terminology Services license; the LOINC SNOMED CT Expression Association is published by Regenstrief Institute as part of the LOINC release and requires authenticated download from loinc.org under the LOINC license.

For programmatic LOINC → SNOMED mapping, use UMLS or the LOINC Expression Association files. For interactive lookup, use the SNOMED CT browser available to your organization or the Regenstrief RELMA desktop tool.

Provide a LOINC code like "2339-0" (Glucose) or "718-7" (Hemoglobin).

Validate a mixed batch of medical codes against their source terminologies. Useful for retrospective analysis of legacy databases — flag codes that no longer exist, surface ICD-10 → ICD-11 replacements, and grade activity status where the terminology exposes it.

For each input { code, terminology }, returns:

• valid: whether the code exists in the source terminology.

• active: whether the code is currently active. Null when the source doesn't expose an explicit active/inactive distinction at category level (CID-10, ATC, ICD-11, RxNorm, MeSH all return null today; SNOMED and LOINC return a real boolean).

• title: the official label/name when available.

• replaced_by: a successor code, populated today only for ICD-10 codes that have a primary ICD-11 mapping in the bundled WHO transition tables.

• source: human-readable provenance of the validation (terminology + release/version).

• error: non-null only when validation couldn't be performed (network error, SNOMED feature flag off, etc.). valid: false + error: null means "code not found"; valid: false + error: set means "couldn't validate".

Terminology is required per code — auto-detection isn't supported because category codes like "A00" exist in both ICD-10 and CID-10. Accepted values: icd11, icd10, snomed, loinc, rxnorm, mesh, atc, cid10.

Hard cap of 50 codes per call; codes are validated in parallel through their respective clients, so total wall time scales with the slowest upstream + its rate limit (worst case ~10 s for a full batch hitting ICD-11).

Ranked unified search for equivalent terms across multiple medical terminologies.

Use this tool to:

• Find the same concept in different coding systems

• Compare how terminologies represent a concept

• Support terminology mapping and data integration

Searches across: ICD-11, SNOMED CT, LOINC, RxNorm, and MeSH. Set target_terminologies to limit which are searched, or set source_terminology to exclude one (e.g. when you already have a code from that terminology and want equivalents elsewhere). The two combine: source is subtracted from targets. limit caps candidates per terminology (default 5, max 10).

Every candidate carries match_score (lexical similarity to the search term, 0-1) and rank (global position across all searched terminologies) — both computed by this server, since upstreams don't expose comparable relevance scores. Candidates from different terminologies whose titles are lexically identical are clustered in groups — a strong same-concept signal (absence of a group is NOT evidence of non-equivalence).

Searches upstreams in English. For official pt-BR content, use the dedicated tools: icd11_search/mesh_search accept language: "pt", and cid10_search is natively Portuguese.

Look up the WHO ATC (Anatomical Therapeutic Chemical) classification(s) for a drug by name.

Use this tool to:

• Find the ATC code for a medication (e.g., "metformin" → A10BA02)

• Identify the therapeutic and pharmacological class hierarchy

• Cross-reference drugs with their international ATC codes

Returns one entry per ATC code the drug belongs to. A single-ingredient drug typically maps to one substance-level code; combination products map to multiple. ATC codes are international (WHO Collaborating Centre); this tool retrieves them via NLM RxClass.

Look up an ATC code at level 1-4 to get its name and hierarchy level.

Use this tool to:

• Resolve an ATC code (e.g., "A10BA") to its class name ("Biguanides")

• Confirm a code exists in the current ATC index

• Identify the level (anatomical / therapeutic / pharmacological / chemical)

Accepts codes 1-5 characters long: "A" (anatomical), "A10" (therapeutic), "A10B" (pharmacological), "A10BA" (chemical). Substance-level codes (7 chars, e.g., "A10BA02") are not exposed by this endpoint — use atc_classify with the drug name to retrieve the substance code.

List the drugs (substances) that belong to an ATC class.

Use this tool to:

• Enumerate all members of a therapeutic class (e.g., "A10BA" → metformin, phenformin)

• Build a list of drugs sharing a pharmacological mechanism

• Explore an ATC subtree at any level

Each member includes its substance-level (7-char) ATC code via source_atc_code, useful for disambiguation when the queried class is at level 1-4. RxNorm's catalog is US-centric; the ATC class names and codes themselves are international.

Search the Brazilian CID-10 (Classificação Estatística Internacional de Doenças, 10ª Revisão) by Portuguese text.

Use this tool to:

• Find CID-10 codes for Brazilian SUS / ANVISA contexts ("infarto", "diabetes", "tuberculose")

• Look up the official Portuguese (CBCD/USP) translation of a clinical term

• Locate codes for billing, epidemiology, and clinical documentation in Brazil

Returns matches from CID-10 categories (3-char) and/or subcategories (4-char). Search is diacritic-insensitive: typing "infeccoes" matches "infecções". This tool searches the Brazilian Portuguese CID-10 V2008 — for the international ICD-11 (current WHO revision, in English by default), use icd11_search.

Look up a specific CID-10 code and return its Portuguese name.

Use this tool to:

• Resolve a code to its Brazilian description ("I21" → "Infarto agudo do miocárdio")

• Confirm a 3-char category or 4-char subcategory exists in CID-10

• Retrieve gender / cause-of-death restriction flags when applicable

Accepts both dotted ("A00.1") and undotted ("A001") forms; returns the canonical display.

List the 22 chapters of CID-10 with their code ranges and Portuguese titles.

Use this tool to:

• See the top-level structure of CID-10 (chapters I-XXII, e.g., "I. Algumas doenças infecciosas e parasitárias", "IX. Doenças do aparelho circulatório")

• Map a code to its chapter by code range (e.g., I00-I99 → chapter IX)

• Build a navigable table of contents for downstream tooling

Returns 22 entries — CID-10 V2008 has not been updated since 2008.

Get one CID-10 chapter and its constituent groups (e.g., "Chapter IX → I00-I02 Febre reumática aguda, I05-I09 Doenças reumáticas crônicas do coração, ...").

Use this tool to:

• Drill from a chapter into its groups

• Build hierarchical browsers

• Find which group contains a code range

Provide a chapter number (1-22).

List the current version, release date, publisher, source URL, and update cadence of every terminology this server queries against.

Useful for pipeline maintainers who need to:

• Confirm which release of ICD-11 / SNOMED / LOINC / RxNorm / MeSH / ATC the server is querying before a batch run.

• Verify the bundled CID-10 (frozen at V2008) and ICD-10 → ICD-11 transition tables (currently 2025-01) match expectations.

• Cite the data version in research artifacts.

Pass terminology to filter to a single entry; otherwise the full set of 8 is returned. The ICD-10 → ICD-11 version reads live from the bundled dataset; everything else is metadata maintained alongside the project release.

Report what diff data is available between two versions of a terminology.

For most terminologies this is guidance only — the server doesn't ship historical snapshots, so the tool points at the publisher's official changelog and explains the cadence. bundled_versions lists the version(s) this server actually has on hand.

For ICD-10 vs ICD-11 specifically, the tool surfaces a real cross-revision summary from the bundled WHO transition tables (the ICD-10 → ICD-11 case is a structural diff between two WHO revisions). Use terminology: "icd10" with no to_version to get the cross-revision summary: total mapped ICD-10 categories, how many are 1:1 vs split into multiple ICD-11 codes, and the average number of alternatives when split.

Inputs:

• terminology (required): which terminology to report on.

• from_version (optional): the version you have data from. If omitted, the tool reports against the currently-bundled version.

• to_version (optional): the version you want to compare to. If omitted, the tool reports against the publisher's latest known release.

This tool is intentionally a metadata + guidance layer, not a diff engine — for terminologies that change frequently (SNOMED, LOINC, RxNorm, MeSH), the publisher's official changelog is the authoritative source.