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AgingResearch.News

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Search aging research papers, evidence, trials and grants; follow topics through Sign in with ARN.

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Last Tested
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Streamable HTTP · MCP 2025-11-25
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Available Tools

23 tools
count_pipelineCount the development pipeline
Read-onlyIdempotent
Inspect

How many drug and therapy programmes there are, grouped by stage, modality, target, hallmark, indication, the developer's country or the developer, with each group's count at each stage. Takes list_assets' filters: by=target with indication=obesity counts the targets of obesity programmes. An account whose plan includes drug and therapy programmes reads every record in full; any other caller reads the outline AgingResearch.News shows on its asset pages.

ParametersJSON Schema
NameRequiredDescriptionDefault
qNoLetters and digits in any of the asset's names or code names (`UBX1325` matches UBX-1325).
byNoWhat to group by.stage
limitNoResults per page, 1 to 25.
stageNoStage: with `indication`, the stage for that indication; otherwise the asset's furthest stage.
targetNoA target: a gene symbol or key (`GLP1R`, `bcl2l1`) or a process key (`mtor`, `cellular-senescence`).
countryNoThe developer's country, ISO 3166 alpha-2 (`US`, `GB`, `CH`).
hallmarkNoA hallmark of aging the asset acts on.
modalityNoThe kind of therapy (see `modality`).
mechanismNoWords that must all appear in the asset's mechanism line (case-insensitive).
indicationNoA disease, by name or entity key (`idiopathic pulmonary fibrosis`, `alzheimer-disease`).
organisationNoAn organisation key: the assets it develops, partners on or licensed out.
find_entitiesFind entities
Read-onlyIdempotent
Inspect

Find what papers are about: interventions such as drugs and diets, genes, biological processes, diseases, biomarkers, organisms, methods, hallmarks and more, most-studied first. Pass a result's type and key to get_entity.

ParametersJSON Schema
NameRequiredDescriptionDefault
qNoMatch on name or key, case-insensitive substring.
typeNoEntity type, e.g. intervention, gene, pathway, component, system, method, hallmark, phenotype, organism, tissue, disease, biomarker, mesh.
limitNoResults per page, 1 to 25.
cursorNoOpaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same.
followFollow a topic
Idempotent
Inspect

Use this when the user asks to follow a drug, gene, process, disease or other entity on AgingResearch.News, so its new papers reach them. Takes the type and key that find_entities or get_entity give. Following is saved to the user's ARN account: new papers on it appear in For you and the daily follow email.

ParametersJSON Schema
NameRequiredDescriptionDefault
keyYesThe entity's key within its type, such as rapamycin.
typeYesThe entity's type, as find_entities or get_entity gives it.
get_assetGet a drug or therapy programme
Read-onlyIdempotent
Inspect

One asset by its key or any code name (ubx1325, UBX-1325, BMS-986278): its developers, partners and licensors, targets, mechanism, modality, every indication with its stage and the trial or source behind it, its lifespan evidence and the news that names it. An account whose plan includes drug and therapy programmes reads every record in full; any other caller reads the outline AgingResearch.News shows on its asset pages.

ParametersJSON Schema
NameRequiredDescriptionDefault
keyYesThe asset's key or a code name.
get_conferenceGet a conference and its abstracts
Read-onlyIdempotent
Inspect

One conference by its id from list_conferences, with its organiser, site and every edition. With edition, that edition's abstracts worth reading, the most relevant first, each with its number, format and the paper it was later published as. Read an abstract in full with get_paper.

ParametersJSON Schema
NameRequiredDescriptionDefault
idYesConference id from list_conferences, e.g. gsa.
limitNoResults per page, 1 to 25.
cursorNoOpaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same.
editionNoAn edition from `editions`, e.g. 2025: list its abstracts.
min_visibilityNoWith `edition`: the lowest visibility band of the abstracts listed (see `judgement.visibility`). Default `visible`, the abstracts the site lists.visible
get_entityGet an entity and its papers
Read-onlyIdempotent
Inspect

One entity, such as intervention rapamycin or disease sarcopenia, with the papers that involve it, newest first, and the role it plays in each. For an intervention, a gene or a process, evidence gives its evidence as structure, never as a grade: the species its findings reach and whether independent labs found the same there, the labs and countries behind them, the findings against, its trials and those with no results posted, its funders and its company ties. A synonym or an old key answers with the entity it now names.

ParametersJSON Schema
NameRequiredDescriptionDefault
keyYesEntity key within its type.
typeYesEntity type.
limitNoResults per page, 1 to 25.
cursorNoOpaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same.
min_relevanceNoLowest aging-relevance score for the papers listed. Default: no filter.
get_paperGet a paper
Read-onlyIdempotent
Inspect

One paper with everything ARN knows about it: its judgement, the language it was published in with its own-language title when that is not English, every author with ORCID iD and institutions, ARN's full story (headline, body, why it matters, caveats) when published, and the entities and claims extracted from it. Takes an ARN paper id such as MED-42823970 from another tool's results.

ParametersJSON Schema
NameRequiredDescriptionDefault
idYesARN paper id, e.g. MED-42823970.
get_trialGet a clinical trial
Read-onlyIdempotent
Inspect

One clinical trial by its registry number (NCT, ISRCTN, ChiCTR, CTRI, CTIS and the rest), with the registry's summary, outcomes and dates, every change ARN recorded and the papers that cite it. A record from the WHO ICTRP carries its attribution and the day WHO processed it, to show with it.

ParametersJSON Schema
NameRequiredDescriptionDefault
nct_idYesThe trial's registry number, e.g. NCT04488601 or ISRCTN12345678.
list_assetsList drug and therapy programmes
Read-onlyIdempotent
Inspect

Drug and therapy programmes in development (assets), furthest stage first: each with its developers and partners, code names, modality, targets, mechanism, indications with the stage of each, hallmarks of aging and lifespan evidence. Narrow by target (a gene symbol such as GLP1R, or a process), mechanism words, modality, hallmark, indication, stage, the developer's country, an organisation or a name. Read one in full with get_asset; count them with count_pipeline. An account whose plan includes drug and therapy programmes reads every record in full; any other caller reads the outline AgingResearch.News shows on its asset pages.

ParametersJSON Schema
NameRequiredDescriptionDefault
qNoLetters and digits in any of the asset's names or code names (`UBX1325` matches UBX-1325).
limitNoResults per page, 1 to 25.
stageNoStage: with `indication`, the stage for that indication; otherwise the asset's furthest stage.
cursorNoOpaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same.
targetNoA target: a gene symbol or key (`GLP1R`, `bcl2l1`) or a process key (`mtor`, `cellular-senescence`).
countryNoThe developer's country, ISO 3166 alpha-2 (`US`, `GB`, `CH`).
hallmarkNoA hallmark of aging the asset acts on.
modalityNoThe kind of therapy (see `modality`).
mechanismNoWords that must all appear in the asset's mechanism line (case-insensitive).
indicationNoA disease, by name or entity key (`idiopathic pulmonary fibrosis`, `alzheimer-disease`).
organisationNoAn organisation key: the assets it develops, partners on or licensed out.
list_claimsList findings
Read-onlyIdempotent
Inspect

Findings extracted from papers as subject, relation and object (for example rapamycin extends_lifespan in Mus musculus), with effect size, conditions and the paper. Narrow by subject, object, relation, organism or paper.

ParametersJSON Schema
NameRequiredDescriptionDefault
limitNoResults per page, 1 to 25.
cursorNoOpaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same.
objectNoObject text, entity name or entity key (case-insensitive substring).
subjectNoSubject text, entity name or entity key (case-insensitive substring).
organismNoOrganism, e.g. Homo sapiens, Mus musculus (case-insensitive substring).
paper_idNoOnly claims from this paper.
relationNoExact relation, e.g. increases, decreases, associated_with, extends_lifespan.
list_conferencesList conferences
Read-onlyIdempotent
Inspect

The conference calendar for aging research and age-related disease: meetings still to come or on, soonest first, then recent ones, each edition with its dates, place and how many of its abstracts ARN holds. Read one, and an edition's abstracts, with get_conference.

ParametersJSON Schema
NameRequiredDescriptionDefault

No parameters

list_feedFeed
Read-onlyIdempotent
Inspect

The sidebar's feed: For you or Top, as story cards.

ParametersJSON Schema
NameRequiredDescriptionDefault
tabNo
list_followsList what the user follows
Read-onlyIdempotent
Inspect

Use this when the user asks what they follow on AgingResearch.News. Lists the drugs, genes, processes and saved searches their ARN account follows, newest first, each with its page on ARN; an entity's id is the type:key that unfollow takes.

ParametersJSON Schema
NameRequiredDescriptionDefault

No parameters

list_grantsList research grants
Read-onlyIdempotent
Inspect

Research grants that bear on human aging, from NIH, the EU (CORDIS), UKRI and Wellcome, judged for aging as papers are, newest award first: title, funder, holder, investigators, amount, funded period, scheme and a link to the record. Narrow by an entity the title names (type:key, as find_entities gives), a funder or holder key, title words or award date. Use it for who funds what, how much and since when.

ParametersJSON Schema
NameRequiredDescriptionDefault
qNoWords of the grant's title ("quoted phrases", OR and -exclusions work).
limitNoResults per page, 1 to 25.
sinceNoOnly grants awarded on or after this date (YYYY-MM-DD).
untilNoOnly grants awarded on or before this date (YYYY-MM-DD).
cursorNoOpaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same.
entityNoOnly grants whose titles name this entity, as `type:key` (see /entities), e.g. `intervention:rapamycin` or `disease:sarcopenia`.
funderNoOnly grants from this funder, by its organisation key or name, e.g. `nia` or `wellcome`.
holderNoOnly grants held by this organisation (its key) or investigator (`person:` and their key), e.g. `buck-institute-for-research-on-aging`.
list_newsList news
Read-onlyIdempotent
Inspect

News about aging research and the longevity industry (companies, funding, trial results, regulators, policy, conferences), one story per event, newest first, in ARN's words with a link to every outlet that covered it. Narrow by words, kind or date.

ParametersJSON Schema
NameRequiredDescriptionDefault
qNoWords that must all appear in the story's headline or summary (case-insensitive).
kindNoOnly stories of this kind.
limitNoResults per page, 1 to 25.
sinceNoOnly stories with coverage on or after this UTC date (YYYY-MM-DD).
cursorNoOpaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same.
list_papersList new papers
Read-onlyIdempotent
Inspect

The newest papers ARN has read, by the date they entered ARN, with the same filters as search_papers and an optional words filter. Use it for what is new in a category, study type or body system, or for one author's papers (author takes a name, or an author_id from get_paper).

ParametersJSON Schema
NameRequiredDescriptionDefault
qNoFull-text filter over title and abstract. Supports "quoted phrases", OR and -exclusions. Results stay in date order; use search_papers for ranked results.
limitNoResults per page, 1 to 25.
sinceNoOnly papers that entered ARN on or after this UTC date (YYYY-MM-DD; a full ISO timestamp is cut to its date).
untilNoOnly papers that entered ARN on or before this UTC date (YYYY-MM-DD).
authorNoPapers by an author. A name matches every author who answers to it: the words in any order, with or without accents, an initial standing for any name it begins (`sinclair d`). An `author_id` from a paper's `authors_full` (an OpenAlex author id such as `A5022713595`, or an ORCID iD) matches that one person.
cursorNoOpaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same.
systemNoBody system key (see `systems`). A paper matches when it involves any of them. Only papers that have been through extraction have systems.
age_linkNoHow the work itself connects to aging (see `judgement.age_link`).
categoryNoCategory slug. A paper matches when its category or its secondary category is listed.
preprintNo`true` for preprints only, `false` for peer-reviewed papers only. Omit for both.
study_typeNoMain source of evidence.
min_relevanceNoLowest aging-relevance score to include (0 to 3, see `judgement.relevance`). Without it, the papers the site shows; 1 adds tangential papers; 0 returns every paper ARN read, most of which are not about aging.
list_questionsList the user's questions to ARN
Read-onlyIdempotent
Inspect

Use this when the user asks about questions they asked AgingResearch.News (Ask) before. Lists their most recent conversations, newest first, each with its title and its address on ARN, where the answer and its sources are.

ParametersJSON Schema
NameRequiredDescriptionDefault
limitNoHow many, 1 to 25.
list_storiesList ARN's stories
Read-onlyIdempotent
Inspect

Stories ARN wrote about new papers and published, newest first, each checked against its paper: a plain-language headline, body, why it matters and caveats, with the paper. Narrow by category, body system, study type or publication date.

ParametersJSON Schema
NameRequiredDescriptionDefault
limitNoResults per page, 1 to 25.
sinceNoOnly stories published on or after this UTC date (YYYY-MM-DD).
untilNoOnly stories published on or before this UTC date (YYYY-MM-DD).
cursorNoOpaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same.
systemNoBody system key (see `systems`). A paper matches when it involves any of them. Only papers that have been through extraction have systems.
categoryNoCategory slug. A paper matches when its category or its secondary category is listed.
study_typeNoMain source of evidence.
list_trialsList clinical trials
Read-onlyIdempotent
Inspect

Clinical trials from ClinicalTrials.gov that bear on human aging, newest registry update first: phase, status, sponsor, size, conditions, interventions and the latest change. Narrow by words, phase, recruitment status, focus, industry sponsor or update date.

ParametersJSON Schema
NameRequiredDescriptionDefault
qNoWords that must all appear in the trial's titles, conditions, interventions, keywords or sponsor (case-insensitive).
focusNoThe trial's main connection to aging (see `focus`).
limitNoResults per page, 1 to 25.
phaseNoPhase: `1` (early phase 1 and phase 1), `2`, `3`, `4`, or `none` for studies with no phase.
sinceNoOnly trials the registry updated on or after this date (YYYY-MM-DD).
cursorNoOpaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same.
statusNoRecruitment status: `recruiting` (recruiting, not yet recruiting or by invitation), `active` (active, not recruiting), `completed`, or `stopped` (terminated, withdrawn or suspended).
industryNo`true` for trials whose lead sponsor is a company, `false` for the rest. Omit for both.
min_relevanceNoLowest aging-relevance score to include (0 to 3, see `relevance`). Default 1.8, the trials /trials shows.
open_arnAgingResearch.News
Read-onlyIdempotent
Inspect

Use this when the user asks to open AgingResearch.News or to see their ARN feed, follows and recent questions in one place. Shows the newest stories ARN wrote (For you when the user is signed in, else Top), what they follow and their recent questions, with search.

ParametersJSON Schema
NameRequiredDescriptionDefault
tabNoWhich feed to open on.
search_arnSearch
Read-onlyIdempotent
Inspect

The sidebar's search: entities and papers matching words, as cards.

ParametersJSON Schema
NameRequiredDescriptionDefault
qYes
search_papersSearch papers
Read-onlyIdempotent
Inspect

Search the biomedical papers ARN has read for words in their titles and abstracts, best match first. Supports "quoted phrases", OR and -exclusions. By default only papers ARN judged relevant to human aging; narrow by study type, category, body system, age link, preprint status, author or the date a paper entered ARN. Each result gives its study type, ARN's judgement, its subjects and ARN's story when one was published. Read one in full with get_paper.

ParametersJSON Schema
NameRequiredDescriptionDefault
qYesSearch terms. Supports "quoted phrases", OR and -exclusions.
limitNoResults per page, 1 to 25.
sinceNoOnly papers that entered ARN on or after this UTC date (YYYY-MM-DD; a full ISO timestamp is cut to its date).
untilNoOnly papers that entered ARN on or before this UTC date (YYYY-MM-DD).
authorNoPapers by an author. A name matches every author who answers to it: the words in any order, with or without accents, an initial standing for any name it begins (`sinclair d`). An `author_id` from a paper's `authors_full` (an OpenAlex author id such as `A5022713595`, or an ORCID iD) matches that one person.
cursorNoOpaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same.
systemNoBody system key (see `systems`). A paper matches when it involves any of them. Only papers that have been through extraction have systems.
age_linkNoHow the work itself connects to aging (see `judgement.age_link`).
categoryNoCategory slug. A paper matches when its category or its secondary category is listed.
preprintNo`true` for preprints only, `false` for peer-reviewed papers only. Omit for both.
study_typeNoMain source of evidence.
min_relevanceNoLowest aging-relevance score to include (0 to 3, see `judgement.relevance`). Without it, the papers the site shows; 1 adds tangential papers; 0 returns every paper ARN read, most of which are not about aging.
unfollowStop following a topic
DestructiveIdempotent
Inspect

Use this when the user asks to stop following a drug, gene, process or other entity on AgingResearch.News. Takes the type and key that list_follows, find_entities or get_entity give. Removes the follow from the user's ARN account.

ParametersJSON Schema
NameRequiredDescriptionDefault
keyYesThe entity's key within its type, such as rapamycin.
typeYesThe entity's type, as find_entities or get_entity gives it.

Tool Schema Changelog

Recent tool additions, removals, and schema changes observed during successful MCP inspections.

  1. 23 tool updates
    • First observedcount_pipeline
    • First observedfind_entities
    • First observedfollow
    • First observedget_asset
    • First observedget_conference
    • First observedget_entity
    • First observedget_paper
    • First observedget_trial
    • First observedlist_assets
    • First observedlist_claims
    • First observedlist_conferences
    • First observedlist_feed
    • First observedlist_follows
    • First observedlist_grants
    • First observedlist_news
    • First observedlist_papers
    • First observedlist_questions
    • First observedlist_stories
    • First observedlist_trials
    • First observedopen_arn
    • First observedsearch_arn
    • First observedsearch_papers
    • First observedunfollow

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