AgingResearch.News
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Search aging research papers, evidence, trials and grants; follow topics through Sign in with ARN.
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- Streamable HTTP · MCP 2025-11-25
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Available Tools
23 toolscount_pipelineCount the development pipelineRead-onlyIdempotentInspect
How many drug and therapy programmes there are, grouped by stage, modality, target, hallmark, indication, the developer's country or the developer, with each group's count at each stage. Takes list_assets' filters: by=target with indication=obesity counts the targets of obesity programmes. An account whose plan includes drug and therapy programmes reads every record in full; any other caller reads the outline AgingResearch.News shows on its asset pages.
| Name | Required | Description | Default |
|---|---|---|---|
| q | No | Letters and digits in any of the asset's names or code names (`UBX1325` matches UBX-1325). | |
| by | No | What to group by. | stage |
| limit | No | Results per page, 1 to 25. | |
| stage | No | Stage: with `indication`, the stage for that indication; otherwise the asset's furthest stage. | |
| target | No | A target: a gene symbol or key (`GLP1R`, `bcl2l1`) or a process key (`mtor`, `cellular-senescence`). | |
| country | No | The developer's country, ISO 3166 alpha-2 (`US`, `GB`, `CH`). | |
| hallmark | No | A hallmark of aging the asset acts on. | |
| modality | No | The kind of therapy (see `modality`). | |
| mechanism | No | Words that must all appear in the asset's mechanism line (case-insensitive). | |
| indication | No | A disease, by name or entity key (`idiopathic pulmonary fibrosis`, `alzheimer-disease`). | |
| organisation | No | An organisation key: the assets it develops, partners on or licensed out. |
find_entitiesFind entitiesRead-onlyIdempotentInspect
Find what papers are about: interventions such as drugs and diets, genes, biological processes, diseases, biomarkers, organisms, methods, hallmarks and more, most-studied first. Pass a result's type and key to get_entity.
| Name | Required | Description | Default |
|---|---|---|---|
| q | No | Match on name or key, case-insensitive substring. | |
| type | No | Entity type, e.g. intervention, gene, pathway, component, system, method, hallmark, phenotype, organism, tissue, disease, biomarker, mesh. | |
| limit | No | Results per page, 1 to 25. | |
| cursor | No | Opaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same. |
followFollow a topicIdempotentInspect
Use this when the user asks to follow a drug, gene, process, disease or other entity on AgingResearch.News, so its new papers reach them. Takes the type and key that find_entities or get_entity give. Following is saved to the user's ARN account: new papers on it appear in For you and the daily follow email.
| Name | Required | Description | Default |
|---|---|---|---|
| key | Yes | The entity's key within its type, such as rapamycin. | |
| type | Yes | The entity's type, as find_entities or get_entity gives it. |
get_assetGet a drug or therapy programmeRead-onlyIdempotentInspect
One asset by its key or any code name (ubx1325, UBX-1325, BMS-986278): its developers, partners and licensors, targets, mechanism, modality, every indication with its stage and the trial or source behind it, its lifespan evidence and the news that names it. An account whose plan includes drug and therapy programmes reads every record in full; any other caller reads the outline AgingResearch.News shows on its asset pages.
| Name | Required | Description | Default |
|---|---|---|---|
| key | Yes | The asset's key or a code name. |
get_conferenceGet a conference and its abstractsRead-onlyIdempotentInspect
One conference by its id from list_conferences, with its organiser, site and every edition. With edition, that edition's abstracts worth reading, the most relevant first, each with its number, format and the paper it was later published as. Read an abstract in full with get_paper.
| Name | Required | Description | Default |
|---|---|---|---|
| id | Yes | Conference id from list_conferences, e.g. gsa. | |
| limit | No | Results per page, 1 to 25. | |
| cursor | No | Opaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same. | |
| edition | No | An edition from `editions`, e.g. 2025: list its abstracts. | |
| min_visibility | No | With `edition`: the lowest visibility band of the abstracts listed (see `judgement.visibility`). Default `visible`, the abstracts the site lists. | visible |
get_entityGet an entity and its papersRead-onlyIdempotentInspect
One entity, such as intervention rapamycin or disease sarcopenia, with the papers that involve it, newest first, and the role it plays in each. For an intervention, a gene or a process, evidence gives its evidence as structure, never as a grade: the species its findings reach and whether independent labs found the same there, the labs and countries behind them, the findings against, its trials and those with no results posted, its funders and its company ties. A synonym or an old key answers with the entity it now names.
| Name | Required | Description | Default |
|---|---|---|---|
| key | Yes | Entity key within its type. | |
| type | Yes | Entity type. | |
| limit | No | Results per page, 1 to 25. | |
| cursor | No | Opaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same. | |
| min_relevance | No | Lowest aging-relevance score for the papers listed. Default: no filter. |
get_paperGet a paperRead-onlyIdempotentInspect
One paper with everything ARN knows about it: its judgement, the language it was published in with its own-language title when that is not English, every author with ORCID iD and institutions, ARN's full story (headline, body, why it matters, caveats) when published, and the entities and claims extracted from it. Takes an ARN paper id such as MED-42823970 from another tool's results.
| Name | Required | Description | Default |
|---|---|---|---|
| id | Yes | ARN paper id, e.g. MED-42823970. |
get_trialGet a clinical trialRead-onlyIdempotentInspect
One clinical trial by its registry number (NCT, ISRCTN, ChiCTR, CTRI, CTIS and the rest), with the registry's summary, outcomes and dates, every change ARN recorded and the papers that cite it. A record from the WHO ICTRP carries its attribution and the day WHO processed it, to show with it.
| Name | Required | Description | Default |
|---|---|---|---|
| nct_id | Yes | The trial's registry number, e.g. NCT04488601 or ISRCTN12345678. |
list_assetsList drug and therapy programmesRead-onlyIdempotentInspect
Drug and therapy programmes in development (assets), furthest stage first: each with its developers and partners, code names, modality, targets, mechanism, indications with the stage of each, hallmarks of aging and lifespan evidence. Narrow by target (a gene symbol such as GLP1R, or a process), mechanism words, modality, hallmark, indication, stage, the developer's country, an organisation or a name. Read one in full with get_asset; count them with count_pipeline. An account whose plan includes drug and therapy programmes reads every record in full; any other caller reads the outline AgingResearch.News shows on its asset pages.
| Name | Required | Description | Default |
|---|---|---|---|
| q | No | Letters and digits in any of the asset's names or code names (`UBX1325` matches UBX-1325). | |
| limit | No | Results per page, 1 to 25. | |
| stage | No | Stage: with `indication`, the stage for that indication; otherwise the asset's furthest stage. | |
| cursor | No | Opaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same. | |
| target | No | A target: a gene symbol or key (`GLP1R`, `bcl2l1`) or a process key (`mtor`, `cellular-senescence`). | |
| country | No | The developer's country, ISO 3166 alpha-2 (`US`, `GB`, `CH`). | |
| hallmark | No | A hallmark of aging the asset acts on. | |
| modality | No | The kind of therapy (see `modality`). | |
| mechanism | No | Words that must all appear in the asset's mechanism line (case-insensitive). | |
| indication | No | A disease, by name or entity key (`idiopathic pulmonary fibrosis`, `alzheimer-disease`). | |
| organisation | No | An organisation key: the assets it develops, partners on or licensed out. |
list_claimsList findingsRead-onlyIdempotentInspect
Findings extracted from papers as subject, relation and object (for example rapamycin extends_lifespan in Mus musculus), with effect size, conditions and the paper. Narrow by subject, object, relation, organism or paper.
| Name | Required | Description | Default |
|---|---|---|---|
| limit | No | Results per page, 1 to 25. | |
| cursor | No | Opaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same. | |
| object | No | Object text, entity name or entity key (case-insensitive substring). | |
| subject | No | Subject text, entity name or entity key (case-insensitive substring). | |
| organism | No | Organism, e.g. Homo sapiens, Mus musculus (case-insensitive substring). | |
| paper_id | No | Only claims from this paper. | |
| relation | No | Exact relation, e.g. increases, decreases, associated_with, extends_lifespan. |
list_conferencesList conferencesRead-onlyIdempotentInspect
The conference calendar for aging research and age-related disease: meetings still to come or on, soonest first, then recent ones, each edition with its dates, place and how many of its abstracts ARN holds. Read one, and an edition's abstracts, with get_conference.
| Name | Required | Description | Default |
|---|---|---|---|
No parameters | |||
list_feedFeedRead-onlyIdempotentInspect
The sidebar's feed: For you or Top, as story cards.
| Name | Required | Description | Default |
|---|---|---|---|
| tab | No |
list_followsList what the user followsRead-onlyIdempotentInspect
Use this when the user asks what they follow on AgingResearch.News. Lists the drugs, genes, processes and saved searches their ARN account follows, newest first, each with its page on ARN; an entity's id is the type:key that unfollow takes.
| Name | Required | Description | Default |
|---|---|---|---|
No parameters | |||
list_grantsList research grantsRead-onlyIdempotentInspect
Research grants that bear on human aging, from NIH, the EU (CORDIS), UKRI and Wellcome, judged for aging as papers are, newest award first: title, funder, holder, investigators, amount, funded period, scheme and a link to the record. Narrow by an entity the title names (type:key, as find_entities gives), a funder or holder key, title words or award date. Use it for who funds what, how much and since when.
| Name | Required | Description | Default |
|---|---|---|---|
| q | No | Words of the grant's title ("quoted phrases", OR and -exclusions work). | |
| limit | No | Results per page, 1 to 25. | |
| since | No | Only grants awarded on or after this date (YYYY-MM-DD). | |
| until | No | Only grants awarded on or before this date (YYYY-MM-DD). | |
| cursor | No | Opaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same. | |
| entity | No | Only grants whose titles name this entity, as `type:key` (see /entities), e.g. `intervention:rapamycin` or `disease:sarcopenia`. | |
| funder | No | Only grants from this funder, by its organisation key or name, e.g. `nia` or `wellcome`. | |
| holder | No | Only grants held by this organisation (its key) or investigator (`person:` and their key), e.g. `buck-institute-for-research-on-aging`. |
list_newsList newsRead-onlyIdempotentInspect
News about aging research and the longevity industry (companies, funding, trial results, regulators, policy, conferences), one story per event, newest first, in ARN's words with a link to every outlet that covered it. Narrow by words, kind or date.
| Name | Required | Description | Default |
|---|---|---|---|
| q | No | Words that must all appear in the story's headline or summary (case-insensitive). | |
| kind | No | Only stories of this kind. | |
| limit | No | Results per page, 1 to 25. | |
| since | No | Only stories with coverage on or after this UTC date (YYYY-MM-DD). | |
| cursor | No | Opaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same. |
list_papersList new papersRead-onlyIdempotentInspect
The newest papers ARN has read, by the date they entered ARN, with the same filters as search_papers and an optional words filter. Use it for what is new in a category, study type or body system, or for one author's papers (author takes a name, or an author_id from get_paper).
| Name | Required | Description | Default |
|---|---|---|---|
| q | No | Full-text filter over title and abstract. Supports "quoted phrases", OR and -exclusions. Results stay in date order; use search_papers for ranked results. | |
| limit | No | Results per page, 1 to 25. | |
| since | No | Only papers that entered ARN on or after this UTC date (YYYY-MM-DD; a full ISO timestamp is cut to its date). | |
| until | No | Only papers that entered ARN on or before this UTC date (YYYY-MM-DD). | |
| author | No | Papers by an author. A name matches every author who answers to it: the words in any order, with or without accents, an initial standing for any name it begins (`sinclair d`). An `author_id` from a paper's `authors_full` (an OpenAlex author id such as `A5022713595`, or an ORCID iD) matches that one person. | |
| cursor | No | Opaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same. | |
| system | No | Body system key (see `systems`). A paper matches when it involves any of them. Only papers that have been through extraction have systems. | |
| age_link | No | How the work itself connects to aging (see `judgement.age_link`). | |
| category | No | Category slug. A paper matches when its category or its secondary category is listed. | |
| preprint | No | `true` for preprints only, `false` for peer-reviewed papers only. Omit for both. | |
| study_type | No | Main source of evidence. | |
| min_relevance | No | Lowest aging-relevance score to include (0 to 3, see `judgement.relevance`). Without it, the papers the site shows; 1 adds tangential papers; 0 returns every paper ARN read, most of which are not about aging. |
list_questionsList the user's questions to ARNRead-onlyIdempotentInspect
Use this when the user asks about questions they asked AgingResearch.News (Ask) before. Lists their most recent conversations, newest first, each with its title and its address on ARN, where the answer and its sources are.
| Name | Required | Description | Default |
|---|---|---|---|
| limit | No | How many, 1 to 25. |
list_storiesList ARN's storiesRead-onlyIdempotentInspect
Stories ARN wrote about new papers and published, newest first, each checked against its paper: a plain-language headline, body, why it matters and caveats, with the paper. Narrow by category, body system, study type or publication date.
| Name | Required | Description | Default |
|---|---|---|---|
| limit | No | Results per page, 1 to 25. | |
| since | No | Only stories published on or after this UTC date (YYYY-MM-DD). | |
| until | No | Only stories published on or before this UTC date (YYYY-MM-DD). | |
| cursor | No | Opaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same. | |
| system | No | Body system key (see `systems`). A paper matches when it involves any of them. Only papers that have been through extraction have systems. | |
| category | No | Category slug. A paper matches when its category or its secondary category is listed. | |
| study_type | No | Main source of evidence. |
list_trialsList clinical trialsRead-onlyIdempotentInspect
Clinical trials from ClinicalTrials.gov that bear on human aging, newest registry update first: phase, status, sponsor, size, conditions, interventions and the latest change. Narrow by words, phase, recruitment status, focus, industry sponsor or update date.
| Name | Required | Description | Default |
|---|---|---|---|
| q | No | Words that must all appear in the trial's titles, conditions, interventions, keywords or sponsor (case-insensitive). | |
| focus | No | The trial's main connection to aging (see `focus`). | |
| limit | No | Results per page, 1 to 25. | |
| phase | No | Phase: `1` (early phase 1 and phase 1), `2`, `3`, `4`, or `none` for studies with no phase. | |
| since | No | Only trials the registry updated on or after this date (YYYY-MM-DD). | |
| cursor | No | Opaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same. | |
| status | No | Recruitment status: `recruiting` (recruiting, not yet recruiting or by invitation), `active` (active, not recruiting), `completed`, or `stopped` (terminated, withdrawn or suspended). | |
| industry | No | `true` for trials whose lead sponsor is a company, `false` for the rest. Omit for both. | |
| min_relevance | No | Lowest aging-relevance score to include (0 to 3, see `relevance`). Default 1.8, the trials /trials shows. |
open_arnAgingResearch.NewsRead-onlyIdempotentInspect
Use this when the user asks to open AgingResearch.News or to see their ARN feed, follows and recent questions in one place. Shows the newest stories ARN wrote (For you when the user is signed in, else Top), what they follow and their recent questions, with search.
| Name | Required | Description | Default |
|---|---|---|---|
| tab | No | Which feed to open on. |
search_arnSearchRead-onlyIdempotentInspect
The sidebar's search: entities and papers matching words, as cards.
| Name | Required | Description | Default |
|---|---|---|---|
| q | Yes |
search_papersSearch papersRead-onlyIdempotentInspect
Search the biomedical papers ARN has read for words in their titles and abstracts, best match first. Supports "quoted phrases", OR and -exclusions. By default only papers ARN judged relevant to human aging; narrow by study type, category, body system, age link, preprint status, author or the date a paper entered ARN. Each result gives its study type, ARN's judgement, its subjects and ARN's story when one was published. Read one in full with get_paper.
| Name | Required | Description | Default |
|---|---|---|---|
| q | Yes | Search terms. Supports "quoted phrases", OR and -exclusions. | |
| limit | No | Results per page, 1 to 25. | |
| since | No | Only papers that entered ARN on or after this UTC date (YYYY-MM-DD; a full ISO timestamp is cut to its date). | |
| until | No | Only papers that entered ARN on or before this UTC date (YYYY-MM-DD). | |
| author | No | Papers by an author. A name matches every author who answers to it: the words in any order, with or without accents, an initial standing for any name it begins (`sinclair d`). An `author_id` from a paper's `authors_full` (an OpenAlex author id such as `A5022713595`, or an ORCID iD) matches that one person. | |
| cursor | No | Opaque cursor from `pagination.next_cursor` of the previous page. Keep the other parameters the same. | |
| system | No | Body system key (see `systems`). A paper matches when it involves any of them. Only papers that have been through extraction have systems. | |
| age_link | No | How the work itself connects to aging (see `judgement.age_link`). | |
| category | No | Category slug. A paper matches when its category or its secondary category is listed. | |
| preprint | No | `true` for preprints only, `false` for peer-reviewed papers only. Omit for both. | |
| study_type | No | Main source of evidence. | |
| min_relevance | No | Lowest aging-relevance score to include (0 to 3, see `judgement.relevance`). Without it, the papers the site shows; 1 adds tangential papers; 0 returns every paper ARN read, most of which are not about aging. |
unfollowStop following a topicDestructiveIdempotentInspect
Use this when the user asks to stop following a drug, gene, process or other entity on AgingResearch.News. Takes the type and key that list_follows, find_entities or get_entity give. Removes the follow from the user's ARN account.
| Name | Required | Description | Default |
|---|---|---|---|
| key | Yes | The entity's key within its type, such as rapamycin. | |
| type | Yes | The entity's type, as find_entities or get_entity gives it. |
Tool Schema Changelog
Recent tool additions, removals, and schema changes observed during successful MCP inspections.
23 tool updates
- First observed
count_pipeline - First observed
find_entities - First observed
follow - First observed
get_asset - First observed
get_conference - First observed
get_entity - First observed
get_paper - First observed
get_trial - First observed
list_assets - First observed
list_claims - First observed
list_conferences - First observed
list_feed - First observed
list_follows - First observed
list_grants - First observed
list_news - First observed
list_papers - First observed
list_questions - First observed
list_stories - First observed
list_trials - First observed
open_arn - First observed
search_arn - First observed
search_papers - First observed
unfollow
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