Catalyst Evidence Graph
A VS Code extension (and one-click/mcp.json setup) that registers the Catalyst evidence graph with GitHub Copilot's agent mode, so Copilot can look up graded evidence for compounds and outcomes and surface the supporting study, population, dose and permalink while working in the editor.
Click on "Deploy Server".
Wait a few minutes for the server to deploy. Once ready, it will show a "Started" state.
In the chat, type
@followed by the MCP server name and your instructions, e.g., "@Catalyst Evidence Graphwhat does creatine do for strength? show the grade and sources"
That's it! The server will respond to your query, and you can continue using it as needed.
Here is a step-by-step guide with screenshots.
Catalyst evidence graph — MCP server, plugins and extensions
Catalyst is a curated evidence graph of what compounds, supplements, nutrients and foods have been shown to do in the human body. This repository connects it to the assistants and editors people already use. The server itself is hosted; everything here only tells a client where it is.
Server: https://catalystproject.ai/mcp — MCP over Streamable HTTP,
read-only, no account, no key.
Registry name: ai.catalystproject/evidence-graph
Setup for every client, the tool list and limits: https://catalystproject.ai/connect
What an assistant gets
Graded findings for a compound or an outcome. Every finding carries a grade from A (well established) to F (speculative), computed from the study behind it — never set by hand — plus the verbatim sentence it was drawn from, the paper, the population and dose, and a permalink to check it.
Relations from reference databases (targets, pathways, reactions), each labelled as a hypothesis rather than a reported result.
A grade describes how strong the evidence is. It is not a recommendation, and nothing here is medical advice. No tool returns a product, a price or a link to buy anything, and no tool ranks what to take.
Related MCP server: zetesis
Install
Client | How |
Claude (web, desktop) | Settings → Connectors → Add custom connector → |
ChatGPT | Developer mode → add a custom app/connector with |
Claude Code (plugin, adds the server and a skill for presenting grades) |
|
Claude Code (server only) |
|
VS Code / GitHub Copilot | The Catalyst Evidence Graph extension (VSIX on the releases page), the one-click link on /connect, or |
Cursor | One-click install, or |
Gemini CLI |
|
Anything else | the JSON below |
{ "mcpServers": { "catalyst": { "url": "https://catalystproject.ai/mcp" } } }VS Code's own file takes a slightly different shape:
{ "servers": { "catalyst": { "type": "http", "url": "https://catalystproject.ai/mcp" } } }In this repository
Path | What it is |
| The entry in the official MCP registry |
| A Claude Code plugin marketplace with one plugin: the server and a |
| A Gemini CLI extension |
| A VS Code extension that registers the server with Copilot's agent mode |
Privacy
The server stores no queries and has no accounts. Rate limits count calls per minute against the client's name and a keyed hash of the network address, never the address itself. Full notice: https://catalystproject.ai/privacy.
Contact
Questions, or something an assistant got wrong from this graph: hello@catalystproject.ai
The code in this repository is MIT-licensed. The graph's content carries the terms on https://catalystproject.ai/terms and per-source licences on https://catalystproject.ai/attribution.
This server cannot be deployed
Maintenance
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