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Opentargets

by io.github.pipeworx-io
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Open Targets MCP — disease/target/drug knowledge graph.

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Status
Unhealthy
Uptime
40.7% over 38 days
Last Tested
Transport
Streamable HTTP
URL
Repository
pipeworx-io/mcp-opentargets
GitHub Stars
0
Server Listing
mcp-opentargets

TDQS

A3.7/5.0

Scored across 38 tools

Disambiguation2/5

The set contains many general-purpose retrieval meta-tools (ask_pipeworx, ask_pipeworx_beta, ask_pipeworx_grounded, deep_research, validate_claim, compare_entities, entity_profile, recent_changes) whose boundaries are subtle and require reading lengthy descriptions; ask_pipeworx_beta is even stated to be identical to ask_pipeworx right now, making them indistinguishable. Polymarket and Open Targets subdomains are clearer, but the overall surface has multiple overlapping entry points that invite misselection.

Naming Consistency3/5

All names use lowercase snake_case, but the conventions are mixed: noun-only (disease, drug, target, search), verb_noun (compare_entities, list_subscriptions), noun_verb (ai_visibility_check, bet_research), and bare verbs (recall, remember, subscribe). The result is readable but not a predictable pattern.

Tool Count2/5

38 tools is heavy for a single MCP server, and the surface spans at least three unrelated domains: Open Targets drug discovery, Pipeworx data gateway/meta-tools, and Polymarket betting. The Open Targets core would need roughly nine tools, while the rest are platform sprawl, so the count is not well-scoped to the server's apparent purpose.

Completeness3/5

For the Open Targets read-only knowledge-graph domain, core lookups exist (search plus disease/target/drug profiles and associations), though some deeper evidence-level queries are absent. Across the broader Pipeworx surface, memory, subscription, and Polymarket tools are present, but the mixed scope makes true coverage hard to assess; there are no catastrophic gaps, but notable omissions remain.

Tool Schema Changelog

Recent tool additions, removals, and schema changes observed during successful MCP inspections.

  1. 1 tool update
    • Changedbet_research2 fields changed
      • changedInput schema / examples
        Previous value: -[
-  {
-    "market": "when-will-bitcoin-hit-150k"
-  },
-  {
-    "market": "https://polymarket.com/event/when-will-bitcoin-hit-150k"
-  }
-]New value: +[
+  {
+    "market": "will-kristi-noem-win-the-2028-republican-presidential-nomination"
+  },
+  {
+    "market": "https://polymarket.com/event/will-kristi-noem-win-the-2028-republican-presidential-nomination"
+  }
+]
      • changedInput schema / properties / market / description
        Previous value: -"Polymarket slug (\"when-will-bitcoin-hit-150k\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k?\"). Dated slugs stop resolving once they settle — Polymarket de-indexes resolved markets — so prefer an undated one."New value: +"Polymarket slug (\"will-kristi-noem-win-the-2028-republican-presidential-nomination\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k?\"). Dated slugs stop resolving once they settle — Polymarket de-indexes resolved markets — so prefer an undated one."
  2. 2 tool updates
    • Changedbet_research2 fields changed
      • changedInput schema / examples
        Previous value: -[
-  {
-    "market": "will-bitcoin-reach-100k-in-july-2026"
-  },
-  {
-    "market": "https://polymarket.com/event/will-bitcoin-hit-150k-by-june-30-2026"
-  }
-]New value: +[
+  {
+    "market": "when-will-bitcoin-hit-150k"
+  },
+  {
+    "market": "https://polymarket.com/event/when-will-bitcoin-hit-150k"
+  }
+]
      • changedInput schema / properties / market / description
        Previous value: -"Polymarket slug (\"will-bitcoin-hit-150k-by-june-30-2026\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k by June 30?\")"New value: +"Polymarket slug (\"when-will-bitcoin-hit-150k\"), full URL (\"https://polymarket.com/event/...\"), or question text (\"Will Bitcoin hit $150k?\"). Dated slugs stop resolving once they settle — Polymarket de-indexes resolved markets — so prefer an undated one."
    • Changedpolymarket_kalshi_spread2 fields changed
      • changedInput schema / examples
        Previous value: -[
-  {
-    "topic": "fed"
-  },
-  {
-    "topic": "btc"
-  }
-]New value: +[
+  {
+    "topic": "fed"
+  },
+  {
+    "topic": "btc"
+  },
+  {
+    "topic": "bitcoin"
+  },
+  {
+    "topic": "fed rate decision"
+  }
+]
      • changedInput schema / properties / topic / description
        Previous value: -"Pre-mapped: fed | btc | cpi | gdp | sp500 | recession | next_pope | next_uk_pm | next_israel_pm | 2028_president"New value: +"Subject to compare. Canonical keys: fed | btc | eth | cpi | gdp | sp500 | recession | next_pope | next_uk_pm | next_israel_pm | 2028_president — but aliases and keywords resolve too (\"bitcoin\", \"fed rate decision\", \"ethereum\", \"inflation\", \"s&p 500\", \"us recession\", \"next pope\", \"2028 election\"). Check resolution.topic_matched_by in the response: \"exact\"/\"alias\" is a curated pairing, \"phrase\"/\"token\" is a keyword guess."

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