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  • PDB MCP Server

    Augmented-Nature
    F
    license
    A
    quality
    F
    maintenance
    A Model Context Protocol (MCP) server that provides access to the Protein Data Bank (PDB) - the worldwide repository of information about the 3D structures of proteins, nucleic acids, and complex assemblies.
    5
    25

  • RELION MCP Server

    kdursunnizam-art
    A
    license
    Not graded
    quality
    C
    maintenance
    Enables AI agents to control RELION 5.x cryo-EM structure determination software through natural language, providing 23 tools for the complete single-particle analysis pipeline.
    4
    MIT

  • UniProt MCP Server

    vitamin3615
    A
    license
    Not graded
    quality
    D
    maintenance
    An MCP server that enables language models to fetch protein information from the UniProt database, including protein details, sequences, functions, and structures.
    MIT

  • OrigeneMCP

    GENTEL-lab
    F
    license
    Not graded
    quality
    D
    maintenance
    An advanced integrated MCP server platform that combines 600+ tools and multiple biomedical databases to enable comprehensive information retrieval across molecules, proteins, genes, and diseases for accelerating therapeutic research.
    38
  • openpgx by open-pgx

    openpgxofficial

    open-pgx
    A
    license
    A
    quality
    D
    maintenance
    Enables AI-driven pharmacogenomic analysis by querying structured genetic variant, drug response, and disease risk data. Supports natural language questions about medications, traits, and health risks based on user genome data, with privacy-first local execution.
    16
    455
    11
    MIT

  • Ensembl MCP Server

    effieklimi
    A
    license
    A
    quality
    D
    maintenance
    A Model Context Protocol server providing LLMs with access to the Ensembl genomics database, enabling AI assistants to query gene information, sequences, variants, and other genomic data across multiple species.
    10
    8
    JavaScript
    MIT

  • Rowan MCP Server

    k-yenko
    A
    license
    B
    quality
    F
    maintenance
    Enables molecular design and simulation through 45 chemistry tools including pKa calculations, geometry optimization, conformer searches, docking, protein cofolding, and ADMET predictions powered by Rowan's computational chemistry platform.
    41
    23
    MIT

  • gnomAD MCP Server

    koido
    A
    license
    B
    quality
    D
    maintenance
    Provides a programmatic interface to the Genome Aggregation Database (gnomAD) API across versions v2.1.1, v3.1.2, and v4.1.0. It enables users to query gene metadata, variant information, population frequencies, and ClinVar data through a unified schema.
    12
    6
    Apache 2.0

  • cxg-census-mcp

    MaxMLang
    A
    license
    B
    quality
    A
    maintenance
    Enables LLM agents to query the CZ CELLxGENE Census single-cell atlas with ontology-aware filters, cost caps, and full provenance, allowing natural language questions about cell types, tissues, and gene expression.
    13
    MIT

  • miEAA3 MCP Server

    kkShrihari
    F
    license
    B
    quality
    D
    maintenance
    Integrates the miEAA 3.x bioinformatics platform with Claude Desktop, enabling microRNA enrichment analysis, identifier conversion between miRBase versions, and miRNA-precursor transformations through natural language.
    4

  • PubChem MCP Server

    k-lordbodin7
    A
    license
    B
    quality
    D
    maintenance
    Enables comprehensive access to PubChem's chemical database with over 110 million compounds. Supports chemical searches, structure analysis, bioactivity data, safety information, and molecular property calculations through 30 specialized tools.
    30
    MIT

  • gnomAD MCP Server

    shukwong
    F
    license
    B
    quality
    D
    maintenance
    Enables AI assistants to query genetic variant data, gene constraints, and population genetics information from the gnomAD (Genome Aggregation Database) through its GraphQL API. Supports searching for genes and variants, retrieving constraint scores, analyzing population frequencies, and accessing genomic coverage data.
    9
    10

  • cBioPortal MCP Server

    pickleton89
    A
    license
    C
    quality
    D
    maintenance
    A server that enables AI assistants to interact with cancer genomics data from cBioPortal, allowing users to explore cancer studies, access genomic data, and retrieve mutations and clinical information.
    17
    6
    MIT