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  • PDBe MCP Servers by PDBeurope

    PDBe MCP Serversofficial

    PDBeurope
    A
    license
    B
    quality
    A
    maintenance
    Provides seamless access to the Protein Data Bank in Europe (PDBe) API and search capabilities, enabling AI clients to query protein structures, perform advanced searches, and retrieve structural biology data.
    33
    37
    Apache 2.0

  • uniprot-mcp

    fzlzjerry
    A
    license
    A
    quality
    B
    maintenance
    MCP server that exposes the UniProt REST API to LLM clients, enabling search and retrieval of protein data via tools like search_uniprotkb, get_entry, and map_ids.
    7
    MIT
  • Bio-MCP BLAST by bio-mcp

    Bio-MCP BLASTofficial

    bio-mcp
    A
    license
    -
    quality
    D
    maintenance
    Enables AI assistants to perform NCBI BLAST sequence similarity searches through natural language, supporting nucleotide and protein searches, custom database creation, and multiple output formats.
    10
    MIT
  • SmartAPI MCP Server by biothings

    SmartAPI MCP Serverofficial

    biothings
    A
    license
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    quality
    A
    maintenance
    Enables integration between MCP-compatible clients and APIs registered in the SmartAPI registry, allowing seamless discovery and interaction with bioinformatics and life sciences APIs through standardized MCP protocols.
    1
    Apache 2.0
  • Bio-MCP FastQC Server by bio-mcp

    Bio-MCP FastQC Serverofficial

    bio-mcp
    A
    license
    -
    quality
    D
    maintenance
    Enables AI assistants to perform quality control analysis on high-throughput sequencing data using FastQC and MultiQC. It supports single-file and batch processing of FASTQ/FASTA files and generates comprehensive, interactive summary reports.
    MIT
  • bio-mcp-evo2 by bio-mcp

    bio-mcp-evo2official

    bio-mcp
    A
    license
    -
    quality
    D
    maintenance
    An MCP server that enables AI assistants to generate, score, and analyze DNA sequences using the evo2 genomic foundation model. It supports multiple execution modes including local GPU, SLURM clusters, and the Nvidia NIM cloud API for tasks like variant effect prediction and sequence embedding.
    MIT
  • galaxy-mcp by galaxyproject

    galaxy-mcpofficial

    galaxyproject
    A
    license
    -
    quality
    A
    maintenance
    MCP server for interacting with Galaxy bioinformatics platform, enabling AI assistants to connect to Galaxy instances, search and execute tools, manage workflows, and access other features.
    37
    MIT

  • pipen-mcp

    pwwang
    A
    license
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    quality
    B
    maintenance
    Exposes pipen bioinformatics pipelines as MCP tools, allowing AI assistants to discover and run complex workflows through a progressive disclosure interface.
    1
    MIT

  • BWA MCP Server

    bio-mcp
    A
    license
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    quality
    D
    maintenance
    Enables AI assistants to perform DNA/RNA sequence alignment using BWA (Burrows-Wheeler Aligner), supporting both short and long read alignment to reference genomes with indexing, BWA-MEM, and BWA-backtrack algorithms.
    MIT

  • mcp-pombase

    pipeworx-io
    A
    license
    -
    quality
    C
    maintenance
    Enables AI agents to query the PomBase fission yeast model-organism database for genetic and molecular data through the Pipeworx MCP gateway.
    4
    MIT

  • Scanpy-MCP

    scmcphub
    A
    license
    -
    quality
    C
    maintenance
    Provides a natural language interface for scRNA-Seq analysis using the Scanpy library, supporting operations such as data preprocessing, clustering, and visualization. It enables AI agents and clients to perform complex single-cell transcriptomics workflows through the Model Context Protocol.
    2
    BSD 3-Clause

  • string-mcp

    meringlab
    A
    license
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    quality
    A
    maintenance
    MCP server that exposes STRING database functionality, allowing AI agents to resolve protein identifiers, retrieve interaction networks, perform homology lookups, and run functional enrichment analysis.
    5
    MIT

  • methods-mcp

    webwebb56
    A
    license
    -
    quality
    D
    maintenance
    Provides MCP tool adapters for Bioconductor methods like limma, DESeq2, and fgsea, enabling statistical analysis of omics data through containerized R execution. It serves as a bridge between MCP clients and bioinformatics tools for reproducible research workflows.
    Apache 2.0

  • UniProt MCP Server

    vitamin3615
    A
    license
    -
    quality
    D
    maintenance
    An MCP server that enables language models to fetch protein information from the UniProt database, including protein details, sequences, functions, and structures.
    MIT

  • decoupler-MCP

    scmcphub
    F
    license
    -
    quality
    C
    maintenance
    Provides a natural language interface for single-cell RNA-Seq analysis using the decoupleR framework. It enables users to perform biological pathway inference, data clustering, and visualization through MCP-compatible AI clients.
    4

  • cellrank-mcp

    scmcphub
    F
    license
    -
    quality
    C
    maintenance
    Enables natural language interaction for scRNA-Seq analysis including preprocessing, clustering, and visualization using the CellRank library. It allows users and agents to perform complex genomic data tasks through standard MCP clients and frameworks.
    2